Gene: Got2

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Name
glutamatic-oxaloacetic transaminase 2, mitochondrial
MGI ID
MGI:95792
Synonyms
mAspAT mitochondrial aspartate aminotransferase FABP-pm plasma membrane fatty acid binding protein Kyat4
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (5)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Got2em1(IMPC)Mbp HOM E9.5 0.00
abnormal embryo turning Got2em1(IMPC)Mbp HOM E9.5 0.00
preweaning lethality, complete penetrance Got2em1(IMPC)Mbp HOM   Early adult 0.00
abnormal visceral yolk sac morphology Got2em1(IMPC)Mbp HOM E9.5 0.00
abnormal pharyngeal arch morphology Got2em1(IMPC)Mbp HOM E9.5 0.00
decreased circulating aspartate transaminase level Got2em1(IMPC)Mbp HET Early adult 1.61×10-09
abnormal craniofacial morphology Got2em1(IMPC)Mbp HET E15.5 0.00
pale yolk sac Got2em1(IMPC)Mbp HOM E9.5 0.00
embryonic growth retardation Got2em1(IMPC)Mbp HOM E9.5 0.00
embryonic growth retardation Got2em1(IMPC)Mbp HET E15.5 0.00
abnormal blood vessel morphology Got2em1(IMPC)Mbp HOM E9.5 0.00
abnormal midbrain development Got2em1(IMPC)Mbp HOM E9.5 0.00
cataract Got2em1(IMPC)Mbp HET Early adult 3.31×10-05
abnormal hindbrain development Got2em1(IMPC)Mbp HOM E9.5 0.00
small spleen Got2em1(IMPC)Mbp HET Early adult 0.00
abnormal neural tube morphology Got2em1(IMPC)Mbp HOM E9.5 0.00
hemorrhage Got2em1(IMPC)Mbp HOM E9.5 0.00
abnormal forebrain development Got2em1(IMPC)Mbp HOM E9.5 0.00
abnormal heart morphology Got2em1(IMPC)Mbp HOM E9.5 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Got2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Got2tm3a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Got2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Got2em1(IMPC)Mbp Exon Deletion Mice, Tissue
Got2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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