Phenotype System Allele Zyg Sex Life Stage P Value
small kidney Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
small heart Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
preweaning lethality, incomplete penetrance Ghtm1.1(KOMP)Vlcg HOM n/a 0.00
abnormal spleen morphology Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
small spleen Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
male infertility Ghtm1.1(KOMP)Vlcg HOM postpartum stage 0.00
enlarged heart Ghtm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal kidney morphology Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
hypoactivity Ghtm1.1(KOMP)Vlcg HOM postnatal 3.71×10-05
abnormal heart morphology Ghtm1.1(KOMP)Vlcg HOM postnatal 0.00
female infertility Ghtm1.1(KOMP)Vlcg HOM postpartum stage 0.00
impaired glucose tolerance Ghtm1.1(KOMP)Vlcg HOM postnatal 2.65×10-28
decreased fasted circulating glucose level Ghtm1.1(KOMP)Vlcg HOM postnatal 7.43×10-07
abnormal behavior Ghtm1.1(KOMP)Vlcg HOM postnatal 2.13×10-05
decreased grip strength Ghtm1.1(KOMP)Vlcg HOM postnatal 1.48×10-23
decreased prepulse inhibition Ghtm1.1(KOMP)Vlcg HOM postnatal 3.21×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (1/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
33 Images
X-ray: XRay Images Lateral Orientation
14 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ghtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ghtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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