Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Ghtm1.1(KOMP)Vlcg HOM Early adult 3.71×10-05
enlarged heart Ghtm1.1(KOMP)Vlcg HET Early adult 0.00
decreased grip strength Ghtm1.1(KOMP)Vlcg HOM Early adult 1.59×10-23
decreased fasting circulating glucose level Ghtm1.1(KOMP)Vlcg HOM Early adult 7.29×10-07
abnormal spleen morphology Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal kidney morphology Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
small heart Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
female infertility Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal heart morphology Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
preweaning lethality, incomplete penetrance Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
impaired glucose tolerance Ghtm1.1(KOMP)Vlcg HOM Early adult 2.77×10-28
small spleen Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
small kidney Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal behavior Ghtm1.1(KOMP)Vlcg HOM Early adult 2.13×10-05
male infertility Ghtm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased prepulse inhibition Ghtm1.1(KOMP)Vlcg HOM Early adult 3.28×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584) N/A
Thymus 2 No  (1/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
7 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ghtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Ghtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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