Gene: Gbx1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
syndactyly Gbx1 HOM postnatal 1.80×10-05
hypoactivity Gbx1tm1b(KOMP)Wtsi HOM postnatal 9.45×10-10
increased circulating glucose level Gbx1 HOM postnatal 6.28×10-10
abnormal behavior Gbx1 HOM postnatal 1.88×10-06
rib fusion Gbx1 HOM postnatal 1.80×10-05
increased hemoglobin content Gbx1 HOM postnatal 1.03×10-05
abnormal gait Gbx1 HOM postnatal 3.65×10-05
abnormal gait Gbx1tm1b(KOMP)Wtsi HOM postnatal 7.69×10-18
vertebral fusion Gbx1 HOM postnatal 1.80×10-05
enlarged urinary bladder Gbx1tm1b(KOMP)Wtsi HOM postnatal 0.00
hypoactivity Gbx1 HOM postnatal 1.64×10-05
limb grasping Gbx1tm1b(KOMP)Wtsi HOM postnatal 6.51×10-05
abnormal behavior Gbx1tm1b(KOMP)Wtsi HOM postnatal 1.11×10-09
improved glucose tolerance Gbx1tm1b(KOMP)Wtsi HOM postnatal 2.91×10-05
decreased hemoglobin content Gbx1 HOM postnatal 1.03×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3  (6/485)  (5/5) N/A
Ear 3  (1/485) N/A
Embryo 3  (1/485)  (5/5) N/A
Eye 3  (1/485) N/A
Foot 3  (1/485) N/A
Forebrain 3  (1/485)  (5/5) N/A
Forelimb 3  (1/485) N/A
Hand 3  (1/485) N/A
Head 3  (5/485)  (5/5) N/A
Heart 3  (1/485) Image Only N/A
Hindbrain 3  (6/485)  (5/5) N/A
Hindlimb 3  (1/485) N/A
Liver 3  (1/485) N/A
Lung 3  (1/485) N/A
Mandibular process 3  (1/485) N/A
Maxillary process 3  (1/485) N/A
Midbrain 3  (1/485) N/A
Oral cavity 3  (1/485) N/A
Skin 3  (1/485) N/A
Tail 3  (1/485)  (1/5) N/A
Tail somite 3  (1/485) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
5 Images
X-ray: XRay Images Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gbx1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gbx1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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