Gene: Gata2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased prepulse inhibition Gata2tm1b(KOMP)Wtsi HET   Early adult 8.42×10-05
abnormal neural tube closure Gata2tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal embryo size Gata2tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal auditory brainstem response Gata2tm1b(KOMP)Wtsi HET   Early adult 2.81×10-06
preweaning lethality, complete penetrance Gata2tm1b(KOMP)Wtsi HOM   Early adult 0.00
abnormal chorioallantoic fusion Gata2tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal ovary morphology Gata2tm1b(KOMP)Wtsi HET Early adult 0.00
abnormal epididymis morphology Gata2tm1b(KOMP)Wtsi HET Early adult 0.00
embryonic lethality prior to tooth bud stage Gata2tm1b(KOMP)Wtsi HOM   E12.5 0.00
abnormal hindbrain development Gata2tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal forebrain development Gata2tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal kidney morphology Gata2tm1b(KOMP)Wtsi HET Early adult 0.00
absent epididymis Gata2tm1b(KOMP)Wtsi HET Early adult 0.00
abnormal embryo size Gata2tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal midbrain development Gata2tm1b(KOMP)Wtsi HET E9.5 0.00
enlarged epididymis Gata2tm1b(KOMP)Wtsi HET Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (1/2)  Section images
Aorta 2 No  (1/590) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/377) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/590) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (20/590)  (1/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590)  (1/2)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/590) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/590) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65) N/A
Brain 3  (6/506) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Ear 3  (1/506)  (2/3) N/A
Embryo 3  (1/507)  (2/3) N/A
Eye 3  (1/506)  (2/3) N/A
Foot 3  (1/506) N/A
Forebrain 3  (1/506) N/A
Forelimb 3  (1/506) N/A
Gut 2  (1/60) N/A
Hand 3  (1/506) N/A
Head 3  (5/506) N/A
Heart 3  (1/506) N/A
Hindbrain 3  (6/506) N/A
Hindlimb 3  (1/506) N/A
Liver 3  (1/504) N/A
Lung 3  (1/504) N/A
Mandibular process 3  (1/506) N/A
Maxillary process 3  (1/506) N/A
Midbrain 3  (1/506) N/A
Nose 2  (1/76)  (2/2) N/A
Oral cavity 3  (1/504) N/A
Chorioallantoic placenta 2  (7/39)  (2/2) N/A
Skeleton 2  (1/76) N/A
Skin 3  (1/506) N/A
Spinal cord 2  (1/73) N/A
Tail 3  (1/506) N/A
Tail somite 3  (1/506) N/A
Trachea 2  (1/60) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
20 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
Adult LacZ: LacZ Images Section
27 Images
Embryo LacZ: LacZ images wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gata2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Gata2tm209271(pL1L2_GT1_DelLacZ_bsd) Targeting vectors
Gata2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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