Fshr | follicle stimulating hormone receptor

GeneMGI:95583Synonyms: follicle-stimulating hormone receptor, FSH-R, +1 more

Physiological systems

15 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton

8 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lean body mass1 supporting datasetFshrtm1(KOMP)VlcghomozygoteEarly adult8.46x10-8 
abnormal startle reflex1 supporting datasetFshrtm1(KOMP)VlcghomozygoteEarly adult9.45x10-5 
increased total body fat amount2 supporting datasetsFshrtm1(KOMP)VlcghomozygoteEarly adult1.25x10-7 
decreased bone mineral content2 supporting datasetsFshrtm1(KOMP)VlcghomozygoteEarly adult1.98x10-11 
decreased bone mineral density1 supporting datasetFshrtm1(KOMP)VlcghomozygoteEarly adult2.3x10-5 
abnormal iris pigmentation1 supporting datasetFshrtm1(KOMP)VlcghomozygoteEarly adult9.81x10-5 
increased fasting circulating glucose level1 supporting datasetFshrtm1(KOMP)VlcghomozygoteEarly adult2.9x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fshrtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fshrtm371386(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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