Gene: Fgfr1

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Name
fibroblast growth factor receptor 1
MGI ID
MGI:95522
Synonyms
Hspy FGFR-I Eask Flt-2 Fgfr-1 Fr1
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Fgfr1tm1.1(KOMP)Vlcg HET E12.5 0.00
embryonic lethality prior to tooth bud stage Fgfr1tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal embryo size Fgfr1tm1.1(KOMP)Vlcg HOM E9.5 0.00
increased respiratory quotient Fgfr1tm1.1(KOMP)Vlcg HET Early adult 3.78×10-05
preweaning lethality, complete penetrance Fgfr1tm1.1(KOMP)Vlcg HOM Early adult 0.00
embryonic lethality prior to organogenesis Fgfr1tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic growth retardation Fgfr1tm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 4  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 4  (1/504) N/A
Embryo 4  (1/505) N/A
Eye 4  (1/504) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504) N/A
Forelimb 4  (1/504) N/A
Gut 2  (1/56) N/A
Hand 4  (1/503) N/A
Head 4  (5/504) N/A
Heart 4  (1/504) N/A
Hindbrain 4  (6/504) N/A
Hindlimb 4  (1/503) N/A
Liver 4  (1/504) N/A
Lung 4  (1/500) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Midbrain 4  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 4  (1/504) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70) N/A
Skin 4  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 4  (1/504) N/A
Tail somite 4  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

Adult LacZ: LacZ Images Section
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
16 Images
Gross Morphology Embryo E9.5
3 Images
Gross Pathology and Tissue Collection
4 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fgfr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Fgfr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Fgfr1tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Fgfr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells