Gene: Fgfr1

Name
fibroblast growth factor receptor 1
MGI ID
MGI:95522
Synonyms
FGFR-I Flt-2 Eask Hspy Fgfr-1
Viability
N/A
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Fgfr1tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
embryonic lethality prior to organogenesis Fgfr1tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal embryo size Fgfr1tm1.1(KOMP)Vlcg HET embryonic day 12.5 0.00
preweaning lethality, complete penetrance Fgfr1tm1.1(KOMP)Vlcg HOM n/a 0.00
embryonic growth retardation Fgfr1tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
increased respiratory quotient Fgfr1tm1.1(KOMP)Vlcg HET postnatal 3.78×10-05
embryonic lethality prior to tooth bud stage Fgfr1tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 4  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 4  (1/485) N/A
Embryo 4  (1/485) N/A
Eye 4  (1/485) N/A
Foot 4  (1/485) N/A
Forebrain 4  (1/485) N/A
Forelimb 4  (1/485) N/A
Gut 2  (1/50) N/A
Hand 4  (1/485) N/A
Head 4  (5/485) N/A
Heart 4  (1/485) N/A
Hindbrain 4  (6/485) N/A
Hindlimb 4  (1/485) N/A
Liver 4  (1/485) N/A
Lung 4  (1/485) N/A
Mandibular process 4  (1/485) N/A
Maxillary process 4  (1/485) N/A
Midbrain 4  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 4  (1/485) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51) N/A
Skin 4  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 4  (1/485) N/A
Tail somite 4  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Section
2 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
4 Images
Gross Morphology Embryo E9.5
3 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Fgfr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Fgfr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Fgfr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Fgfr1tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells