Gene: Fgf7

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Name
fibroblast growth factor 7
MGI ID
MGI:95521
Synonyms
Kgf Keratinocyte growth factor
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
impaired righting response Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 6.33×10-06
irregularly shaped pupil Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 9.05×10-05
abnormal bone structure Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 1.13×10-06
mydriasis Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 3.05×10-05
decreased bone mineral content Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 1.41×10-08
decreased lean body mass Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 2.89×10-06
abnormal iris morphology Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 6.09×10-05
abnormal placement of pupils Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 5.80×10-05
abnormal startle reflex Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 4.67×10-11
long tail Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 7.56×10-06
impaired pupillary reflex Fgf7tm1e.1(EUCOMM)Hmgu HOM Early adult 2.60×10-07

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504)  (4/4) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503)  (4/4) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504)  (2/4) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (4/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
11 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fgf7tm1e(EUCOMM)Hmgu Targeted, non-conditional allele Mice
Fgf7tm1e.1(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Fgf7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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