Gene: Fgf3

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
abnormal tail morphology Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
preweaning lethality, complete penetrance Fgf3tm4b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal tail morphology Fgf3tm4b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal embryo size Fgf3tm4b(EUCOMM)Hmgu HOM E12.5 0.00
enlarged lymph nodes Fgf3tm4b(EUCOMM)Hmgu HOM Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 4  (1/57) N/A
Axial skeleton 4  (1/61) N/A
Brain 4  (6/504)  (3/4) N/A
Central nervous system ganglion 4  (1/70) N/A
Cranium 4  (1/61) N/A
Dorsal root ganglion 4  (1/57) N/A
Ear 4  (1/504)  (2/4) N/A
Embryo 4  (1/505)  (2/4) N/A
Outer ear 4  (1/66)  (2/4) N/A
Eye 4  (1/504) N/A
Femur pre-cartilage condensation 4  (1/52) N/A
Foot 4  (1/504) N/A
Forearm 4  (1/297) N/A
Forebrain 4  (1/504)  (4/4) N/A
Forelimb 4  (1/504) N/A
Fronto-nasal process 4  (1/58)  (2/4) N/A
Gut 4  (1/56) N/A
Hand 4  (1/503) N/A
Head 4  (5/504)  (4/4) N/A
Head mesenchyme 4  (1/57)  (2/4) N/A
Heart 4  (1/504) N/A
Heart ventricle 4  (1/57) N/A
Hindbrain 4  (6/504)  (4/4) N/A
Hindlimb 4  (1/503) N/A
Humerus pre-cartilage condensation 4  (1/61) N/A
Inner ear 4  (1/61) N/A
Intestine 4  (1/55) N/A
Liver 4  (1/504) N/A
Lower leg 4  (1/297) N/A
Lung 4  (1/500) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Mesonephros of female 4  (1/52) N/A
Mesonephros of male 4  (1/52) N/A
Metanephros 4  (1/52) N/A
Midbrain 4  (1/504)  (2/4) N/A
Nasal septum 4  (1/57) N/A
Nose 4  (1/70) N/A
Notochord 4  (1/57) N/A
Oral cavity 4  (1/504) N/A
Outflow tract 4  (1/57) N/A
Pancreas 4  (1/52) N/A
Pericardium 4  (1/52) N/A
Pharynx 4  (1/52) N/A
Radius-ulna pre-cartilage condensation 4  (1/61) N/A
Rib pre-cartilage condensation 4  (1/54) N/A
Skeleton 4  (1/70) N/A
Skin 4  (1/504) N/A
Spinal cord 4  (1/69) N/A
Stomach 4  (1/52) N/A
Tail 4  (1/504)  (4/4) N/A
Tail somite 4  (1/504)  (4/4) N/A
Thoracic vertebral cartilage condensation 4  (1/52) N/A
Tongue 4  (1/52) N/A
Trachea 4  (1/56) N/A
Trunk mesenchyme 4  (1/57) N/A
Umbilical artery embryonic part 4  (1/57) N/A
Umbilical vein embryonic part 4  (1/57) N/A
Upper arm 4  (1/297) N/A
Upper leg 4  (1/297) N/A
Urinary system 4  (1/56) N/A
Vibrissa 4  (1/66) N/A

 Associated Images

X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
3 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fgf3tm4a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Fgf3tm4b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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