Gene: Fgf3

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal tail morphology Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
enlarged lymph nodes Fgf3tm4b(EUCOMM)Hmgu HET Early adult 0.00
abnormal embryo size Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
preweaning lethality, complete penetrance Fgf3tm4b(EUCOMM)Hmgu HOM   Early adult 0.00
abnormal radius morphology Fgf3tm4b(EUCOMM)Hmgu HET   Early adult 9.97×10-05
unresponsive to tactile stimuli Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
unresponsive to tactile stimuli Fgf3tm4b(EUCOMM)Hmgu HET E18.5 0.00
no spontaneous movement Fgf3tm4b(EUCOMM)Hmgu HOM E18.5 0.00
abnormal retina morphology Fgf3tm4b(EUCOMM)Hmgu HET   Early adult 8.05×10-05
abnormal embryo size Fgf3tm4b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal ulna morphology Fgf3tm4b(EUCOMM)Hmgu HET   Early adult 9.97×10-05
increased spleen weight Fgf3tm4b(EUCOMM)Hmgu HET Early adult 2.82×10-21
abnormal tail morphology Fgf3tm4b(EUCOMM)Hmgu HOM E12.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/382)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
3 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Immunophenotyping: Panel B FCS file(s)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fgf3tm4b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Fgf3tm4a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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