Gene: Eif2b4

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Name
eukaryotic translation initiation factor 2B, subunit 4 delta
MGI ID
MGI:95300
Synonyms
Eif2b
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Eif2b4tm1b(KOMP)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Eif2b4tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Eif2b4tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal eye morphology Eif2b4tm1b(KOMP)Wtsi HET Early adult 0.00
enlarged heart Eif2b4tm1b(KOMP)Wtsi HET Early adult 0.00
short tibia Eif2b4tm1b(KOMP)Wtsi HET Early adult 2.69×10-05
abnormal embryo size Eif2b4tm1b(KOMP)Wtsi HET E9.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Blood 4 No N/A
Bone marrow 4 No N/A
Brain 4 No  (2/4)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No  (1/4)  Section images
Cartilage tissue 4 No N/A
Cecum 4 No  (12/379)  (2/4) N/A
Cerebellum 4 No  (4/4)  Wholemount images  Section images
Cerebral cortex 4 No N/A
Chest bone 4 No N/A
Colon 4 No  (12/127)  (2/4) N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127) N/A
Epididymis 4 No  (18/134)  (2/4)  Section images
Esophagus 4 No  (7/415)  (1/4)  Section images
Eye 4 No N/A
Gall bladder 4 No N/A
Gonadal fat pad 4 No  (1/4)  Section images
Harderian gland 4 No  (2/4)  Section images
Heart 4 No N/A
Hindlimb 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 4 No  (14/127)  (2/4) N/A
Jejunum 4 No  (6/127) N/A
Kidney 4 No  (18/584)  (4/4)  Wholemount images  Section images
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No  (2/4)  Wholemount images
Mesenteric lymph node 4 No N/A
Midbrain 4 No  (4/4)  Wholemount images  Section images
Olfactory lobe 4 No  (3/4)  Wholemount images  Section images
Ovary 4 No  (1/584) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/584)  (2/4)  Wholemount images
Parathyroid gland 4 No  (1/4)  Section images
Parotid gland 4 No N/A
Penis 4 No N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (2/4)  Wholemount images  Section images
Prostate gland 4 No  (12/584)  (1/4)  Section images
Quadriceps 4 No N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (3/4)  Wholemount images  Section images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (2/4) N/A
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 No N/A
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (2/584)  (1/4)  Section images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584)  (2/4)  Wholemount images
Tongue 4 No  (5/127) N/A
Trachea 4 No N/A
Trigeminal V nerve 4 No N/A
Urinary bladder 4 No N/A
Uterus 4 No N/A
Vagina 4 No N/A
Vas deferens 4 No  (15/388)  (2/4)  Section images
Vascular system 4 No N/A
Vesicular gland 4 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 5  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 5  (1/504) N/A
Embryo 5  (1/505)  (2/5) N/A
Eye 5  (1/504)  (2/5) N/A
Foot 5  (1/504) N/A
Forebrain 5  (1/504) N/A
Forelimb 5  (1/504) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 5  (1/503) N/A
Head 5  (5/504) N/A
Heart 5  (1/504)  (2/5) N/A
Hindbrain 5  (6/504) N/A
Hindlimb 5  (1/503) N/A
Liver 5  (1/504) N/A
Lung 5  (1/500) N/A
Mandibular process 5  (1/504) N/A
Maxillary process 5  (1/504) N/A
Midbrain 5  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 5  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 5  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 5  (1/504) N/A
Tail somite 5  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
38 Images
Embryo LacZ: LacZ images wholemount
20 Images
Adult LacZ: LacZ Images Wholemount
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
40 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Eif2b4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Eif2b4tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Eif2b4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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