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Genes Phenotypes Help, News, Blog

Gene: Egr1

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Name
early growth response 1
MGI ID
MGI:95295
Synonyms
TIS8 NGFIA Krox24 Zenk Zif268 ETR103 Krox-24 Krox-1 Egr-1 Zfp-6 NGF1-A A530045N19Rik NGFI-A
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (14) Measurements chart (219) All data table (1228)
Expression & images (30) Disease models (0) Histopathology (2) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased monocyte cell number Egr1tm1b(NCOM)Mfgc HET   Early adult 6.56×10-05
abnormal midbrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
decreased body length Egr1tm1b(NCOM)Mfgc HET Early adult 3.86×10-05
embryonic growth retardation Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
small uterus Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal optic disk morphology Egr1tm1b(NCOM)Mfgc HOM   Early adult 1.07×10-06
preweaning lethality, incomplete penetrance Egr1tm1b(NCOM)Mfgc HOM   Early adult 0.00
short tibia Egr1tm1b(NCOM)Mfgc HET Early adult 8.95×10-06
increased grip strength Egr1tm1b(NCOM)Mfgc HET Early adult 7.43×10-05
abnormal embryo size Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal forebrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal hindbrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
absent seminal vesicle Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal neural tube closure Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (3/3) N/A
4  (6/505)  (3/5) N/A
2  (1/73)  (3/3) N/A
4  (1/505)  (3/5) N/A
4  (1/506)  (5/5) N/A
4  (1/505)  (3/5) N/A
4  (1/505) N/A
4  (1/505)  (3/5) N/A
4  (1/505)  (3/5) N/A
2  (1/59)  (3/3) N/A
4  (1/505) N/A
4  (5/505)  (3/5) N/A
4  (1/505)  (3/5) N/A
4  (6/505)  (3/5) N/A
4  (1/505)  (3/5) N/A
4  (1/503)  (3/5) N/A
4  (1/503)  (3/5) N/A
4  (1/505) N/A
4  (1/505) N/A
4  (1/505)  (3/5) N/A
2  (1/75)  (3/3) N/A
4  (1/503)  (3/5) N/A
2  (7/39)  (3/3) N/A
2  (1/75)  (3/3) N/A
4  (1/505)  (3/5) N/A
2  (1/72)  (3/3) N/A
4  (1/505)  (3/5) N/A
4  (1/505)  (3/5) N/A
2  (1/59)  (3/3) N/A
2  (1/59)  (3/3) N/A

 Associated Images

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Gross Morphology Embryo E9.5
4 Images
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Embryo LacZ: LacZ images wholemount
20 Images
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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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Gross Pathology and Tissue Collection
18 Images
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Histopathology
10 Images
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Eye Morphology: Images Ophthalmoscopy
6 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Immunophenotyping: Panel A FCS file(s)
2 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Ovary - developmental and structural abnormality Egr1tm1b(NCOM)Mfgc HOM Early adult
Testes - process of degenerative change Egr1tm1b(NCOM)Mfgc HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Egr1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Egr1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Egr1tm214497(L1L2_Bact_P) Targeting vectors
Egr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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