banner
Genes Phenotypes Help, News, Blog

Gene: Egr1

Log in to follow
Name
early growth response 1
MGI ID
MGI:95295
Synonyms
TIS8 NGFIA Krox24 Zenk Zif268 ETR103 Krox-24 Krox-1 Egr-1 Zfp-6 NGF1-A A530045N19Rik NGFI-A
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (16) Measurements chart (235) All data table (1305)
Expression & images (30) Disease models (0) Histopathology (3) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
absent seminal vesicle Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal embryo size Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
female infertility Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal midbrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
preweaning lethality, incomplete penetrance Egr1tm1b(NCOM)Mfgc HOM   Early adult 0.00
increased monocyte cell number Egr1tm1b(NCOM)Mfgc HET   Early adult 4.53×10-05
abnormal optic disk morphology Egr1tm1b(NCOM)Mfgc HOM Early adult 2.61×10-05
embryonic growth retardation Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
short tibia Egr1tm1b(NCOM)Mfgc HET Early adult 8.95×10-06
small uterus Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
increased grip strength Egr1tm1b(NCOM)Mfgc HET Early adult 6.05×10-05
male infertility Egr1tm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal hindbrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal neural tube closure Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00
decreased body length Egr1tm1b(NCOM)Mfgc HET Early adult 3.86×10-05
abnormal forebrain development Egr1tm1b(NCOM)Mfgc HOM E9.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/63)  (3/3) N/A
Brain 4  (6/507)  (3/5) N/A
Central nervous system ganglion 2  (1/72)  (3/3) N/A
Ear 4  (1/507)  (3/5) N/A
Embryo 4  (1/508)  (5/5) N/A
Eye 4  (1/507)  (3/5) N/A
Footplate 4  (1/507) N/A
Forebrain 4  (1/507)  (3/5) N/A
Forelimb 4  (1/507)  (3/5) N/A
Gut 2  (1/58)  (3/3) N/A
Handplate 4  (1/507) N/A
Head 4  (5/507)  (3/5) N/A
Heart 4  (1/507)  (3/5) N/A
Hindbrain 4  (6/507)  (3/5) N/A
Hindlimb 4  (1/507)  (3/5) N/A
Liver 4  (1/502)  (3/5) N/A
Lung 4  (1/502)  (3/5) N/A
Mandibular process 4  (1/507) N/A
Maxillary process 4  (1/507) N/A
Midbrain 4  (1/507)  (3/5) N/A
Nose 2  (1/77)  (3/3) N/A
Oral cavity 4  (1/502)  (3/5) N/A
Placenta 2  (7/42)  (3/3) N/A
Skeleton 2  (1/77)  (3/3) N/A
Skin 4  (1/507)  (3/5) N/A
Spinal cord 2  (1/71)  (3/3) N/A
Tail 4  (1/507)  (3/5) N/A
Tail somite group 4  (1/507)  (3/5) N/A
Trachea 2  (1/58)  (3/3) N/A
Urinary system 2  (1/58)  (3/3) N/A

 Associated Images

thumbnail
Gross Pathology and Tissue Collection
18 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
thumbnail
Histopathology
10 Images
thumbnail
Eye Morphology: Images Ophthalmoscopy
10 Images
thumbnail
X-ray: XRay Images Skull Lateral Orientation
14 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
thumbnail
Embryo LacZ: LacZ images wholemount
20 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
thumbnail
Gross Morphology Embryo E9.5
4 Images
Immunophenotyping: Panel A FCS file(s)
2 Images
Immunophenotyping: Panel B FCS file(s)
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Ovary - MPATH pathological process term follicular atresia Egr1tm1b(NCOM)Mfgc HOM Early adult
Testis - MPATH pathological process term spermatogenesis defect Egr1tm1b(NCOM)Mfgc HOM Early adult
Testis - MPATH pathological process term dysplasia Egr1tm1b(NCOM)Mfgc HOM Early adult

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Egr1tm214497(L1L2_Bact_P) Targeting vectors
Egr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Egr1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Egr1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter