Gene: Egr1

Name
early growth response 1
MGI ID
MGI:95295
Synonyms
A530045N19Rik Zif268 Krox24 Krox-1 Egr-1 NGFIA TIS8 Zfp-6 NGF1-A Zenk NGFI-A Krox-24 ETR103
Viability
Homozygous - Subviable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal midbrain development Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
small uterus Egr1tm1b(NCOM)Mfgc HOM postnatal 0.00
embryonic lethality prior to tooth bud stage Egr1tm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
preweaning lethality, incomplete penetrance Egr1tm1b(NCOM)Mfgc HOM n/a 0.00
absent seminal vesicle Egr1tm1b(NCOM)Mfgc HOM postnatal 0.00
male infertility Egr1tm1b(NCOM)Mfgc HOM postpartum stage 0.00
abnormal neural tube closure Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
abnormal forebrain development Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
female infertility Egr1tm1b(NCOM)Mfgc HOM postpartum stage 0.00
decreased body length Egr1tm1b(NCOM)Mfgc HET postnatal 3.90×10-07
embryonic growth retardation Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
abnormal embryo size Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
abnormal hindbrain development Egr1tm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
short tibia Egr1tm1b(NCOM)Mfgc HET postnatal 1.21×10-09

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (3/3) N/A
Brain 4  (6/485)  (3/5) N/A
Central nervous system ganglion 2  (1/51)  (3/3) N/A
Ear 4  (1/485)  (3/5) N/A
Embryo 4  (1/485)  (5/5) N/A
Eye 4  (1/485)  (3/5) N/A
Foot 4  (1/485) N/A
Forebrain 4  (1/485)  (3/5) N/A
Forelimb 4  (1/485)  (3/5) N/A
Gut 2  (1/50)  (3/3) N/A
Hand 4  (1/485) N/A
Head 4  (5/485)  (3/5) N/A
Heart 4  (1/485)  (3/5) N/A
Hindbrain 4  (6/485)  (3/5) N/A
Hindlimb 4  (1/485)  (3/5) N/A
Liver 4  (1/485)  (3/5) N/A
Lung 4  (1/485)  (3/5) N/A
Mandibular process 4  (1/485) N/A
Maxillary process 4  (1/485) N/A
Midbrain 4  (1/485)  (3/5) N/A
Nose 2  (1/51)  (3/3) N/A
Oral cavity 4  (1/485)  (3/5) N/A
2  (7/25)  (3/3) N/A
Skeleton 2  (1/51)  (3/3) N/A
Skin 4  (1/485)  (3/5) N/A
Spinal cord 2  (1/50)  (3/3) N/A
Tail 4  (1/485)  (3/5) N/A
Tail somite 4  (1/485)  (3/5) N/A
Trachea 2  (1/50)  (3/3) N/A
Urinary system 2  (1/50)  (3/3) N/A

 Associated Images

Gross Pathology and Tissue Collection
18 Images
Gross Morphology Embryo E9.5
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Dorso Ventral
14 Images
Histopathology
10 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
X-ray: XRay Images Lateral Orientation
14 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Ovary - developmental and structural abnormality Egr1tm1b(NCOM)Mfgc HOM postnatal
Testes - process of degenerative change Egr1tm1b(NCOM)Mfgc HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Egr1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice
Egr1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Egr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Egr1tm214497(L1L2_Bact_P) Targeting vectors

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