Gene: Dpp4

Name
dipeptidylpeptidase 4
MGI ID
MGI:94919
Synonyms
Dpp-4 THAM Cd26
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (365) Expression & images (0) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - thickness HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Alanine aminotransferase HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.191 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / LVPWd HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.199 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Bulging eye HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / RR HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.778 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left vitreous humour thickness HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.000617 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Creatinine HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0175 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Iris/Pupil HOM 6f:7m Fisher Exact Test framework 0.175 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Mean cell hemoglobin concentration HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0190 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal deposits HOM 4f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Indirect Calorimetry / Total food intake HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.918 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Eosinophil differential count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.519 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Percentage center time HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.904 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.316 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Body length HOM 6f:7m Mixed Model framework, generalized least squares, equation withWeight 0.387 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Lens Opacity HOM 6f:7m Fisher Exact Test framework 0.0178 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Periphery distance travelled HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.464 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Retina (combined) HOM 4f:8m Not processed Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal mineralization HOM 6f:8m Fisher Exact Test framework 0.282 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Calcium HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.190 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / HR HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.603 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 0.0652 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Hematocrit HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.132 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - ear HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.725 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.000509 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Pupil Dilation HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Fat mass HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0676 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.553 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.100 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left inner nuclear layer HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.584 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Phosphorus HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.304 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Tremor HOM 7f:8m Fisher Exact Test framework 0.214 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Viability Primary Screen / Outcome HOM 28f:27m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Large Unstained Cell (LUC) count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0969 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Indirect Calorimetry / Total water intake HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.971 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Lymphocyte cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000519 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / ST HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.218 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Indirect Calorimetry / Respiratory Exchange Ratio HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.673 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Center distance travelled HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.529 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.831 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal vascularization HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Retinal Blood Vessels Pattern HOM 4f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Triglycerides HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0399 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right total retinal thickness HOM 4f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_062_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:8m Fisher Exact Test framework 0.588 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Platelet count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.685 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 0.0505 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Total protein HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0166 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Pupil Position HOM 6f:7m Fisher Exact Test framework 0.104 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Fat/Body weight HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.00820 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Latency to center entry HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.580 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Eyelid closure HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / LVIDd HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.728 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Iris transilumination HOM 4f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Aspartate aminotransferase HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.367 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Eosinophil cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.637 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.930 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Hemoglobin HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0508 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Whole arena resting time HOM 7f:8m Mixed Model framework, generalized least squares, equation withWeight 0.934 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Vitreous HOM 4f:8m Fisher Exact Test framework 0.00330 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Teeth presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Lens HOM 6f:7m Fisher Exact Test framework 0.0168 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / QTc HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0730 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0133 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Head size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left corneal thickness HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.596 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Optic Disc HOM 4f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Center average speed HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0265 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Narrow eye opening HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Heart Weight / Heart weight HOM 4f:8m Mixed Model framework, generalized least squares, equation withWeight 0.000189 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 6f:7m Mixed Model framework, generalized least squares, equation withWeight 0.0141 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Neutrophil differential count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000356 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - snout HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / HDL-cholesterol HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.530 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Persistence of hyaloid vascular system HOM 4f:8m Fisher Exact Test framework 0.0816 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.998 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0708 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Pupil Shape HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Periphery average speed HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.215 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Eye HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right vitreous humor thickness HOM 4f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_087_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Lymphocyte differential count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.323 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right anterior chamber depth HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_061_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Monocyte differential count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.294 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Heart Weight / Tibia length HOM 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HWT_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Lean/Body weight HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0978 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Distance travelled - total HOM 7f:8m Mixed Model framework, generalized least squares, equation withWeight 0.394 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Snout size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / PR HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.591 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Synechia HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.173 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Total cholesterol HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.361 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - size HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Periphery permanence time HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.904 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right inner nuclear layer HOM 4f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_063_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Albumin HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.741 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00309 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / HR HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.523 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / LVAWd HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.297 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Aggression HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Number of center entries HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.585 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Grip Strength / Forelimb grip strength measurement mean HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00249 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Startle response HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Eyelid morphology HOM 6f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Mean cell volume HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.893 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - back HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Cornea HOM 6f:8m Fisher Exact Test framework 0.00756 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Center permanence time HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.904 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left anterior chamber depth HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_067_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.664 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Basophil cell count HOM 4f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_037_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 6f:7m Mixed Model framework, generalized least squares, equation withWeight 0.170 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Red blood cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.145 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.269 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Iris Pigmentation HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.517 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Retinal Blood Vessels HOM 4f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Lacrimation HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Neutrophil cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0141 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right corneal thickness HOM 4f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_060_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.143 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Periphery resting time HOM 7f:8m Mixed Model framework, generalized least squares, equation withWeight 0.948 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left outer nuclear layer HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.667 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal Sclerization HOM 4f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Alkaline phosphatase HOM 4f:8m Mixed Model framework, generalized least squares, equation withWeight 0.943 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - length HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Eye Hemorrhage or Blood Presence HOM 6f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Monocyte cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000741 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Number of rears - total HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.729 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.613 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Rotarod / Latency to fall mean HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.380 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Bone Area HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0426 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Fusion between cornea and lens HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - color - head HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Mean corpuscular hemoglobin HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.537 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / LVIDs HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0702 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Right outer nuclear layer HOM 4f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_EYE_064_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0183 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Large Unstained Cell (LUC) differential count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.311 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forepaw - size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Total bilirubin HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.123 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / BMC/Body weight HOM 6f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0210 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / Basophil differential count HOM 4f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_038_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 7f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Center resting time HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.981 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Clinical Chemistry / Glucose HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.823 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Retinal Blood Vessels Structure HOM 4f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Left total retinal thickness HOM 4f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.754 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal ulcer HOM 6f:8m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Echo / Fractional Shortening HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00410 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Gait HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Electrocardiogram (ECG) / QRS HOM 5f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.320 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Ears HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Tail - presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Dpp4tm1b(EUCOMM)Wtsi ICS Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.450 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Body Composition (DEXA lean/fat) / Lean mass HOM 6f:7m Mixed Model framework, generalized least squares, equation withWeight 0.104 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Tibia length HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.334 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Pupil Light Response HOM 6f:7m Fisher Exact Test framework 1.00 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Eye Morphology / Corneal opacity HOM 6f:8m Fisher Exact Test framework 0.00411 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Open Field / Whole arena average speed HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.142 Success
Dpp4tm1b(EUCOMM)Wtsi ICS X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Dpp4tm1b(EUCOMM)Wtsi ICS Hematology / White blood cell count HOM 4f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000173 Success
Dpp4tm1b(EUCOMM)Wtsi ICS Combined SHIRPA and Dysmorphology / Skin color - tail HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dpp4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dpp4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Dpp4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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