Dhfr | dihydrofolate reductase
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Hematopoietic system Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
Human diseases caused by Dhfr mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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