Adipor2 | adiponectin receptor 2

GeneMGI:93830Synonyms: D6Ucla1e, 1110001I14Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased neutrophil cell number2 supporting datasetsAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adult2.15x10-13 
decreased grip strength1 supporting datasetAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adult4.61x10-7 
limb grasping1 supporting datasetAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adult4.65x10-9 
small testis1 supporting datasetAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased lymphocyte cell number1 supporting datasetAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adult9.64x10-7 
male infertility1 supporting datasetAdipor2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a100% (2/2)0.7% (4/570)
aortaheterozygoten/a100% (2/2)0.19% (1/533)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/a100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoten/a100% (2/2)0% (0/588)
cartilage tissueheterozygoten/a100% (2/2)0.22% (1/454)
cerebellumheterozygoten/a100% (2/2)0.56% (3/532)
cerebral cortexheterozygoten/a100% (2/2)0.41% (2/491)
esophagusheterozygoten/a100% (2/2)1.67% (7/419)
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Histopathology

IMPC related publications

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Adipor2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Adipor2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Adipor2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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