Bach1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1

GeneMGI:894680Synonyms: 6230421P05Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Skeleton Cardiovascular system Mortality/aging

12 No significant impact

7 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues

Phenotypes

increased bone mineral density1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult8.33x10-5 
increased circulating sodium level1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult2.45x10-6 
increased heart rate variability1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult3.81x10-6 
cardiovascular system phenotype1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult6.16x10-8 
increased heart weight1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult5.24x10-7 
increased fasting circulating glucose level1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult1.04x10-16 
preweaning lethality, incomplete penetrance1 supporting datasetBach1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased bone mineral content1 supporting datasetBach1tm1.1(KOMP)VlcgheterozygoteEarly adult1.83x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bach1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Bach1tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Bach1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Bach1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Bach1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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