Gene: Bach2

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Name
BTB and CNC homology, basic leucine zipper transcription factor 2
MGI ID
MGI:894679
Synonyms
E030004N02Rik
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal prepulse inhibition Bach2tm1b(EUCOMM)Wtsi HOM Early adult 2.63×10-11
abnormal bone mineral density Bach2tm1a(EUCOMM)Wtsi HOM Early adult 9.17×10-07
decreased circulating insulin level Bach2tm1a(EUCOMM)Wtsi HOM Early adult 8.34×10-13
abnormal circulating creatinine level Bach2tm1b(EUCOMM)Wtsi HOM Early adult 6.69×10-06
decreased prepulse inhibition Bach2tm1b(EUCOMM)Wtsi HOM Early adult 3.13×10-07
decreased CD11b-high dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal circulating glucose level Bach2tm1b(EUCOMM)Wtsi HOM Early adult 3.05×10-08
increased neutrophil cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased food intake Bach2tm1b(EUCOMM)Wtsi HOM Early adult 1.28×10-22
abnormal grip strength Bach2tm1b(EUCOMM)Wtsi HOM Early adult 6.16×10-05
increased memory-marker NK cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
limb grasping Bach2tm1b(EUCOMM)Wtsi HOM Early adult 1.15×10-14
increased KLRG1+ CD4 alpha beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased circulating glucose level Bach2tm1b(EUCOMM)Wtsi HOM Early adult 1.48×10-06
abnormal pulmonary respiratory rate Bach2tm1b(EUCOMM)Wtsi HOM Early adult 4.99×10-09
increased KLRG1-positive CD4-negative NK T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased effector memory T-helper cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased Ly6C low monocyte number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased respiratory quotient Bach2tm1b(EUCOMM)Wtsi HOM Early adult 4.54×10-22
increased KLRG1-positive NK cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal fasting circulating glucose level Bach2tm1a(EUCOMM)Wtsi HOM Early adult 2.20×10-05
increased NK cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased memory-marker NK cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased CD4-positive, alpha-beta memory T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
hyperactivity Bach2tm1b(EUCOMM)Wtsi HOM Early adult 4.47×10-07
increased CD103-positive CD11b-low dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal tibia morphology Bach2tm1b(EUCOMM)Wtsi HOM Early adult 5.00×10-05
decreased follicular B cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased CD8-positive, naive alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased immature B cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal locomotor activation Bach2tm1b(EUCOMM)Wtsi HOM Early adult 2.00×10-15
increased effector memory CD8-positive, alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased KLRG1-positive gamma-delta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased B cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased effector memory CD8-positive, alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal bone structure Bach2tm1a(EUCOMM)Wtsi HOM Early adult 9.25×10-05
abnormal bone mineralization Bach2tm1a(EUCOMM)Wtsi HOM Early adult 5.95×10-06
increased CD8-positive, alpha-beta memory T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased memory-marker CD4-negative NK T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased KLRG1+ CD8 alpha beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased CD11b-low dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased monocyte cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased eosinophil cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal bone mineral density Bach2tm1b(EUCOMM)Wtsi HOM Early adult 1.51×10-05
decreased vertical activity Bach2tm1b(EUCOMM)Wtsi HOM Early adult 1.73×10-15
increased macrophage cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased circulating unsaturated transferrin level Bach2tm1b(EUCOMM)Wtsi HOM Early adult 8.81×10-06
abnormal circulating creatinine level Bach2tm1a(EUCOMM)Wtsi HOM Early adult 3.91×10-07
abnormal food intake Bach2tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased grip strength Bach2tm1b(EUCOMM)Wtsi HOM Early adult 5.55×10-07
decreased mature B cell number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal respiratory quotient Bach2tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased Ly6C high monocyte number Bach2tm1a(EUCOMM)Wtsi HOM Early adult 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
50 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Ear epidermis immunophenotyping
47 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
35 Images
X-ray: XRay Images Forepaw
15 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
Eye Morphology: Images Slit Lamp
1 Images
Legacy Phenotype Associated Images

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 Disease Models

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MGI Allele Allele Type Produced
Bach2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Bach2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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