Gene: Bach2

Name
BTB and CNC homology, basic leucine zipper transcription factor 2
MGI ID
MGI:894679
Synonyms
E030004N02Rik
Viability
N/A
View
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased monocyte cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD11b-high dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased bone mineral content Bach2tm1a(EUCOMM)Wtsi HOM postnatal 1.66×10-08
decreased bone mineral density Bach2tm1a(EUCOMM)Wtsi HOM postnatal 3.90×10-08
increased KLRG1-positive gamma-delta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased memory-marker CD4-negative NK T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased KLRG1-positive CD4-negative NK T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased circulating insulin level Bach2tm1a(EUCOMM)Wtsi HOM postnatal 4.09×10-06
increased CD11b-low dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased KLRG1+ CD8 alpha beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased Ly6C low monocyte number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased KLRG1+ CD4 alpha beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased B cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased food intake Bach2tm1b(EUCOMM)Wtsi HOM postnatal 5.80×10-14
increased memory-marker NK cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased respiratory quotient Bach2tm1b(EUCOMM)Wtsi HOM postnatal 2.57×10-13
limb grasping Bach2tm1b(EUCOMM)Wtsi HOM postnatal 2.22×10-11
decreased effector memory CD8-positive, alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased macrophage cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased pulmonary respiratory rate Bach2tm1b(EUCOMM)Wtsi HOM postnatal 7.55×10-06
increased neutrophil cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased grip strength Bach2tm1b(EUCOMM)Wtsi HOM postnatal 3.85×10-06
hyperactivity Bach2tm1b(EUCOMM)Wtsi HOM postnatal 2.55×10-07
increased CD103-positive CD11b-low dendritic cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 2.12×10-05
increased effector memory T-helper cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased KLRG1-positive NK cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased eosinophil cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased NK cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased Ly6C high monocyte number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased memory-marker NK cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased grip strength Bach2tm1b(EUCOMM)Wtsi HOM postnatal 4.63×10-06
increased effector memory CD8-positive, alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased circulating glucose level Bach2tm1b(EUCOMM)Wtsi HOM postnatal 2.88×10-08
decreased vertical activity Bach2tm1b(EUCOMM)Wtsi HOM postnatal 1.43×10-21
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased immature B cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD8-positive, naive alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased mature B cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased follicular B cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased circulating creatinine level Bach2tm1a(EUCOMM)Wtsi HOM postnatal 2.40×10-05
increased effector memory CD4-positive, alpha-beta T cell number Bach2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased circulating unsaturated transferrin level Bach2tm1b(EUCOMM)Wtsi HOM postnatal 2.08×10-10
decreased prepulse inhibition Bach2tm1b(EUCOMM)Wtsi HOM postnatal 1.18×10-10
abnormal bone structure Bach2tm1a(EUCOMM)Wtsi HOM postnatal 3.33×10-06

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 Expression

Expression data not available

 Associated Images

Brain Histopathology: Cerebellar Section
1 Images
Brain Histopathology: Striatal Section
3 Images
Brain Histopathology: Hippocampal section
3 Images
DSS Histology
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Forepaw
15 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
X-ray: XRay Images Dorso Ventral
43 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Bach2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Bach2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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