Gene: Aurka

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Name
aurora kinase A
MGI ID
MGI:894678
Synonyms
Ayk1 Ark1 IAK AIRK1 aurora A Aurora-A Stk6 IAK1
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal bone structure Aurkatm1b(EUCOMM)Hmgu HET Early adult 2.56×10-05
increased mean corpuscular hemoglobin Aurkatm1b(EUCOMM)Hmgu HET   Early adult 5.07×10-05
embryonic lethality prior to tooth bud stage Aurkatm1b(EUCOMM)Hmgu HOM   E12.5 0.00
embryonic lethality prior to organogenesis Aurkatm1b(EUCOMM)Hmgu HOM   E9.5 0.00
decreased leukocyte cell number Aurkatm1b(EUCOMM)Hmgu HET   Early adult 5.76×10-05
sclerocornea Aurkatm1b(EUCOMM)Hmgu HET Early adult 1.16×10-05
preweaning lethality, complete penetrance Aurkatm1b(EUCOMM)Hmgu HOM   Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2)  Section images
2 No  (1/584) N/A
2 No  (1/2)  Section images
2 No  (4/584) N/A
2 No  (2/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (3/584) N/A
2 No  (2/584) N/A
2 No  (17/133)  (1/2)  Section images
2 No  (7/408)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/584) N/A
2 No  (3/584) N/A
2 No  (2/584) N/A
2 No  (21/584)  (2/2)  Section images
2 No  (10/584)  (2/2)  Section images
2 No N/A
2 No  (1/584) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No  (1/584)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/584)  (1/2)  Section images
2 No  (2/584) N/A
2 No N/A
2 No  (1/584)  (1/2)  Section images
2 No  (12/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (9/584)  (1/2)  Section images
2 No  (3/584) N/A
2 No  (3/584) N/A
2 No  (12/584)  (1/2)  Section images
2 No  (3/584) N/A
2 No  (2/131)  (2/2)  Section images
2 No  (6/584)  (1/2)  Section images
2 No N/A
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (3/584) N/A
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (2/2) N/A
Dorsal root ganglion 1  (1/59) Image Only N/A
Ear 2  (1/507)  (2/2) N/A
Embryo 2  (1/508)  (2/2)  Wholemount images
Eye 2  (1/507)  (2/2) N/A
Footplate 2  (1/507)  (2/2) N/A
Forebrain 2  (1/507)  (2/2) N/A
Forelimb 2  (1/507)  (2/2) N/A
Fronto-nasal process 1  (1/60) Image Only N/A
Handplate 2  (1/507)  (2/2) N/A
Head 2  (5/507)  (2/2) N/A
Heart 2  (1/507)  (2/2) N/A
Hindbrain 2  (6/507)  (2/2) N/A
Hindlimb 2  (1/507)  (2/2) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502)  (1/2) N/A
Mandibular process 2  (1/507)  (2/2) N/A
Maxillary process 2  (1/507)  (2/2) N/A
Midbrain 2  (1/507)  (2/2) N/A
Nose 1  (1/77)  (1/1) N/A
Oral cavity 2  (1/502)  (1/2) N/A
Skin 2  (1/507)  (2/2) N/A
Spinal cord 1  (1/71)  (1/1) N/A
Tail 2  (1/507)  (2/2) N/A
Tail somite group 2  (1/507)  (1/2) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
8 Images
Original Image
Adult LacZ: LacZ Images Section
18 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Sleep Wake: Wake state (bmp file)
4 Images
Eye Morphology: Images Slit Lamp
2 Images
Electroretinography 2: Rod and cone PDF
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Aurkatm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Aurkatm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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