Gene: Aurka

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Name
aurora kinase A
MGI ID
MGI:894678
Synonyms
Ayk1 Ark1 IAK AIRK1 aurora A Aurora-A Stk6 IAK1
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular hemoglobin Aurkatm1b(EUCOMM)Hmgu HET   Early adult 5.29×10-05
preweaning lethality, complete penetrance Aurkatm1b(EUCOMM)Hmgu HOM   Early adult 0.00
embryonic lethality prior to tooth bud stage Aurkatm1b(EUCOMM)Hmgu HOM   E12.5 0.00
embryonic lethality prior to organogenesis Aurkatm1b(EUCOMM)Hmgu HOM   E9.5 0.00
sclerocornea Aurkatm1b(EUCOMM)Hmgu HET Early adult 1.33×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2)  Section images
2 No  (1/583) N/A
2 No  (1/2)  Section images
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (18/132)  (1/2)  Section images
2 No  (7/407)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2)  Section images
2 No  (10/583)  (2/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/583)  (1/2)  Section images
2 No  (2/583) N/A
2 No N/A
2 No  (1/583)  (1/2)  Section images
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583)  (1/2)  Section images
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583)  (1/2)  Section images
2 No  (3/583) N/A
2 No  (2/130)  (2/2)  Section images
2 No  (6/583)  (1/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/2) N/A
1  (1/60) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2)  Wholemount images
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
1  (1/61) Image Only N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503) N/A
2  (1/503)  (1/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
1  (1/75)  (1/1) N/A
2  (1/503)  (1/2) N/A
2  (1/505)  (2/2) N/A
1  (1/72)  (1/1) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (1/2) N/A

 Associated Images

X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Original Image
Adult LacZ: LacZ Images Section
18 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
8 Images
Sleep Wake: Wake state (bmp file)
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Aurkatm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Aurkatm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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