Gene: Aurka

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Name
aurora kinase A
MGI ID
MGI:894678
Synonyms
Ark1 Ayk1 AIRK1 IAK aurora A Aurora-A Stk6 IAK1
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Aurkatm1b(EUCOMM)Hmgu HOM   Early adult 0.00
abnormal neural tube closure Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00
abnormal heart looping Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00
embryonic lethality prior to tooth bud stage Aurkatm1b(EUCOMM)Hmgu HOM   E12.5 0.00
abnormal tail bud morphology Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00
abnormal embryo size Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00
abnormal embryo turning Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00
sclerocornea Aurkatm1b(EUCOMM)Hmgu HET Early adult 1.45×10-05
embryonic lethality prior to organogenesis Aurkatm1b(EUCOMM)Hmgu HOM   E9.5 0.00
abnormal forebrain development Aurkatm1b(EUCOMM)Hmgu HET E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Section images
Aorta 2 No  (1/590) N/A
Bone marrow 2 No  (1/2)  Section images
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (1/2)  Section images
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/590)  (1/2)  Section images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (1/2)  Section images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590)  (1/2)  Section images
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (1/2)  Section images
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/2) N/A
Dorsal root ganglion 1  (1/61) Image Only N/A
Ear 2  (1/506)  (2/2) N/A
Embryo 2  (1/507)  (2/2)  Wholemount images
Eye 2  (1/506)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 1  (1/62) Image Only N/A
Hand 2  (1/506)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/506)  (2/2) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504)  (1/2) N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (2/2) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nose 1  (1/76)  (1/1) N/A
Oral cavity 2  (1/504)  (1/2) N/A
Skin 2  (1/506)  (2/2) N/A
Spinal cord 1  (1/73)  (1/1) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506)  (1/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Sleep Wake: Wake state (bmp file)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
Original Image
Adult LacZ: LacZ Images Section
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Aurkatm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Aurkatm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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