Gene: Ppfibp2

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Name
PTPRF interacting protein, binding protein 2 (liprin beta 2)
MGI ID
MGI:894649
Synonyms
liprin beta 2 Cclp1
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal vocalization Ppfibp2em1(IMPC)Tcp HOM   Late adult 5.70×10-07
abnormal retinal vasculature morphology Ppfibp2em1(IMPC)Tcp HOM Late adult 5.27×10-13
increased anxiety-related response Ppfibp2em1(IMPC)Tcp HOM Early adult 1.73×10-05
enlarged lymph nodes Ppfibp2em1(IMPC)Tcp HOM Early adult 0.00
abnormal lens morphology Ppfibp2em1(IMPC)Tcp HOM   Late adult 6.21×10-06
decreased grip strength Ppfibp2em1(IMPC)Tcp HOM Middle aged adult 3.74×10-05
hypoactivity Ppfibp2em1(IMPC)Tcp HOM Early adult 3.22×10-05
abnormal optic disk morphology Ppfibp2em1(IMPC)Tcp HOM Late adult 2.28×10-14
decreased grip strength Ppfibp2em1(IMPC)Tcp HOM Late adult 3.71×10-06
abnormal behavior Ppfibp2em1(IMPC)Tcp HOM Early adult 5.57×10-05
abnormal skin morphology Ppfibp2em1(IMPC)Tcp HOM Early adult 0.00
increased monocyte cell number Ppfibp2em1(IMPC)Tcp HOM Late adult 1.96×10-05
cataract Ppfibp2em1(IMPC)Tcp HOM   Late adult 6.13×10-05
abnormal retinal blood vessel morphology Ppfibp2em1(IMPC)Tcp HOM Late adult 2.28×10-14
increased thigmotaxis Ppfibp2em1(IMPC)Tcp HOM Early adult 5.57×10-05
persistence of hyaloid vascular system Ppfibp2em1(IMPC)Tcp HOM Late adult 6.40×10-14

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Histopathology
17 Images
Eye Morphology: Images Ophthalmoscopy
50 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Slit Lamp
163 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
96 Images
Gross Pathology and Tissue Collection
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppfibp2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ppfibp2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ppfibp2em1(IMPC)Tcp Exon Deletion Mice, Tissue

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