Septin8 | septin 8
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Hematopoietic system Behavior/neurological Skeleton
15 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased mean corpuscular volume | 1 supporting dataset | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.58x10-5 | ||
increased startle reflex | 3 supporting datasets | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.07x10-7 | ||
decreased bone mineral density | 1 supporting dataset | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.67x10-5 | ||
abnormal startle reflex | 1 supporting dataset | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.35x10-5 | ||
decreased prepulse inhibition | 2 supporting datasets | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 6.92x10-5 | ||
abnormal locomotor activation | 1 supporting dataset | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.33x10-5 | ||
increased circulating phosphate level | 1 supporting dataset | Septin8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 9.67x10-7 |
| | | | | | | | | |
External links
No external links available for Septin8.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Septin8tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Septin8tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |