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Gene: Scarb1

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Name
scavenger receptor class B, member 1
MGI ID
MGI:893578
Synonyms
D5Ertd460e Srb1 Cd36l1 Cla-1 SRBI SR-BI Hlb398 Hdlq1 Chohd1 Chohd1
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (155) All data table (574)
Expression & images (49) Disease models (0) Order (7)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased heart rate Scarb1tm1b(EUCOMM)Wtsi HET   Early adult 6.33×10-06
dilated heart left ventricle Scarb1tm1b(EUCOMM)Wtsi HOM   Early adult 2.60×10-05
enlarged spleen Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased circulating cholesterol level Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 6.83×10-16
decreased cardiac muscle contractility Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 3.70×10-05
decreased vertical activity Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 7.37×10-07
increased lean body mass Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 6.52×10-06
enlarged heart Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
prolonged QT interval Scarb1tm1b(EUCOMM)Wtsi HET Early adult 1.74×10-06
abnormal sinus arrhythmia Scarb1tm1b(EUCOMM)Wtsi HET Early adult 5.46×10-07
decreased total body fat amount Scarb1tm1b(EUCOMM)Wtsi HOM Early adult 2.30×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583)  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583) N/A
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Wholemount images
Spleen 2 No  (3/583)  (2/2)  Wholemount images
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583)  (2/2)  Wholemount images
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vas deferens 2 No  (15/382)  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No  (2/2)  Wholemount images
LacZ Wholemount Images
adipose tissue (3)
Ovary expression
Oviduct expression
White Adipose Tissue expression
MA:0000058
MA:0000384
MA:0000385
cardiovascular system (2)
Cartilage tissue expression
Vascular System expression
MA:0002718
MA:0000104
digestive system (1)
Liver expression
MA:0000358
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Lower Urinary Tract expression
Prostate gland ambiguous
MA:0002636
MA:0000404
immune system (2)
Spleen expression
MA:0000141
integumental system (1)
Skin expression
MA:0000151
nervous system (4)
Brain expression
Brain expression
Brain expression
Brain expression
Brain expression
Brain expression
Brainstem expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000191
MA:0000169
MA:0000891
MA:0000168
MA:0002413
MA:0000185
MA:0000173
postnatal mouse (18)
Adrenal gland expression
MA:0000116
reproductive system (4)
Lower Urinary Tract expression
Prostate gland ambiguous
MA:0002636
MA:0000404
respiratory system (1)
Trachea expression
Thyroid gland expression
Parathyroid gland expression
MA:0000128
MA:0000441
MA:0000129
set of connective tissues (4)
Cartilage tissue expression
Vascular System expression
MA:0002718
MA:0000104
trunk (13)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
20 Images
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X-ray: XRay Images Skull Lateral Orientation
20 Images
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X-ray: XRay Images Forepaw
20 Images
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Adult LacZ: LacZ Images Wholemount
18 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
20 Images
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X-ray: XRay Images Whole Body Lateral Orientation
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Scarb1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Scarb1tm41571(L1L2_Bact_P) Targeting vectors
Scarb1tm358832(L1L2_Bact_P) Targeting vectors
Scarb1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Scarb1tm41571(L1L2_gt1) Targeting vectors
Scarb1tm41571(L1L2_st1) Targeting vectors
Scarb1tm41571(L1L2_st2) Targeting vectors

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