Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological
13 No significant impact
5 Not tested
Data collections
Gene metrics:19Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
abnormal gait | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 5.44x10-5 | ||
increased circulating serum albumin level | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.79x10-9 | ||
decreased locomotor activity | 5 supporting datasets | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.33x10-5 | ||
thrombocytosis | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 5.91x10-10 | ||
increased neutrophil cell number | 2 supporting datasets | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 1.28x10-6 | ||
decreased locomotor activity | 8 supporting datasets | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 9.1x10-15 | ||
increased fasting circulating glucose level | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 3.67x10-6 | ||
increased total body fat amount | 2 supporting datasets | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.61x10-6 | ||
decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 6.27x10-5 | ||
tremors | 1 supporting dataset | Cyp19a1tm1b(EUCOMM)Hmgu | homozygote | Late adult | 7.32x10-5 |
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External links
No external links available for Cyp19a1.
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Cyp19a1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Cyp19a1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Cyp19a1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |