Csnk2a2 | casein kinase 2, alpha prime polypeptide

GeneMGI:88547Synonyms: CK2, 1110035J23Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

11 No significant impact

4 Not tested

Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult9.2x10-6 
abnormal testis morphology1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased circulating HDL cholesterol level1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult7.37x10-6 
abnormal skin morphology1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating alkaline phosphatase level1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult1.09x10-9 
decreased anxiety-related response1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult6.86x10-6 
abnormal spleen morphology1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased thigmotaxis2 supporting datasetsCsnk2a2em1(IMPC)MbphomozygoteEarly adult9.13x10-6 
increased circulating bilirubin level1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult3.48x10-6 
increased vertical activity1 supporting datasetCsnk2a2em1(IMPC)MbphomozygoteEarly adult1.25x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Csnk2a2em1(IMPC)MbpExon Deletionmouse
Csnk2a2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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