Gene: Cox5b

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
prenatal lethality prior to heart atrial septation Cox5btm2b(EUCOMM)Hmgu HOM E15.5 0.00
preweaning lethality, complete penetrance Cox5btm2b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal embryonic autopod plate morphology Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00
persistence of hyaloid vascular system Cox5btm2b(EUCOMM)Hmgu HET Early adult 7.06×10-05
pale liver Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal embryo size Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal liver size Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal skin coloration Cox5btm2b(EUCOMM)Hmgu HET Early adult 4.31×10-07
decreased blood urea nitrogen level Cox5btm2b(EUCOMM)Hmgu HET Early adult 1.95×10-05
pallor Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal placenta size Cox5btm2b(EUCOMM)Hmgu HOM E12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57) N/A
Axial skeleton 2  (1/61) N/A
Brain 2  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Cranium 2  (1/61) N/A
Dorsal root ganglion 2  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505) N/A
Outer ear 2  (1/66) N/A
Eye 2  (1/504) N/A
Femur pre-cartilage condensation 2  (1/52) N/A
Foot 2  (1/504) N/A
Forearm 2  (1/297) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504) N/A
Fronto-nasal process 2  (1/58) N/A
Gut 2  (1/56) N/A
Hand 2  (1/503) N/A
Head 2  (5/504) N/A
Head mesenchyme 2  (1/57) N/A
Heart 2  (1/504) N/A
Heart ventricle 2  (1/57) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Humerus pre-cartilage condensation 2  (1/61) N/A
Inner ear 2  (1/61) N/A
Intestine 2  (1/55) N/A
Liver 2  (1/504) N/A
Lower leg 2  (1/297) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Mesonephros of female 2  (1/52) N/A
Mesonephros of male 2  (1/52) N/A
Metanephros 2  (1/52) N/A
Midbrain 2  (1/504) N/A
Nasal septum 2  (1/57) N/A
Nose 2  (1/70) N/A
Notochord 2  (1/57) N/A
Oral cavity 2  (1/504) N/A
Outflow tract 2  (1/57) N/A
Pancreas 2  (1/52) N/A
Pericardium 2  (1/52) N/A
Pharynx 2  (1/52) N/A
Radius-ulna pre-cartilage condensation 2  (1/61) N/A
Rib pre-cartilage condensation 2  (1/54) N/A
Skeleton 2  (1/70) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69) N/A
Stomach 2  (1/52) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A
Thoracic vertebral cartilage condensation 2  (1/52) N/A
Tongue 2  (1/52) N/A
Trachea 2  (1/56) N/A
Trunk mesenchyme 2  (1/57) N/A
Umbilical artery embryonic part 2  (1/57) N/A
Umbilical vein embryonic part 2  (1/57) N/A
Upper arm 2  (1/297) N/A
Upper leg 2  (1/297) N/A
Urinary system 2  (1/56) N/A
Vibrissa 2  (1/66) N/A

 Associated Images

Eye Morphology: VIP of right eye
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Eye Morphology: VIP of right fundus
14 Images
Eye Morphology: VIP of left fundus
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
Adult LacZ: LacZ Images Wholemount
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cox5btm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cox5btm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Cox5btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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