Gene: Cox4i1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
pallor Cox4i1tm1.1(KOMP)Vlcg HET E9.5 0.00
decreased grip strength Cox4i1tm1.1(KOMP)Vlcg HET Early adult 7.65×10-05
abnormal embryo size Cox4i1tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal neural tube closure Cox4i1tm1.1(KOMP)Vlcg HET E9.5 0.00
preweaning lethality, complete penetrance Cox4i1tm1.1(KOMP)Vlcg HOM Early adult 0.00
embryonic lethality prior to organogenesis Cox4i1tm1.1(KOMP)Vlcg HOM E9.5 0.00
increased or absent threshold for auditory brainstem response Cox4i1tm1.1(KOMP)Vlcg HET Early adult 7.81×10-05
abnormal midbrain development Cox4i1tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal hindbrain development Cox4i1tm1.1(KOMP)Vlcg HET E9.5 0.00
hyperactivity Cox4i1tm1.1(KOMP)Vlcg HET Early adult 1.71×10-05
embryonic lethality prior to tooth bud stage Cox4i1tm1.1(KOMP)Vlcg HOM E12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (1/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (1/2) N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (1/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (1/2) N/A
Skin 2 No  (1/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
White adipose tissue 2 No  (1/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 4  (6/504)  (2/4) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 4  (1/504)  (2/4) N/A
Embryo 4  (1/505)  (2/4) N/A
Eye 4  (1/504) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504)  (2/4) N/A
Forelimb 4  (1/504) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 4  (1/503) N/A
Head 4  (5/504)  (2/4) N/A
Heart 4  (1/504)  (2/4) N/A
Hindbrain 4  (6/504)  (2/4) N/A
Hindlimb 4  (1/503) N/A
Liver 4  (1/504)  (2/4) N/A
Lung 4  (1/500)  (2/4) N/A
Mandibular process 4  (1/504)  (2/4) N/A
Maxillary process 4  (1/504)  (2/4) N/A
Midbrain 4  (1/504)  (2/4) N/A
Nose 2  (1/70) N/A
Oral cavity 4  (1/504)  (2/4) N/A
Skeleton 2  (1/70) N/A
Skin 4  (1/504) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 4  (1/504) N/A
Tail somite 4  (1/504) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Histopathology
9 Images
Adult LacZ: LacZ Images Section
12 Images
Gross Pathology and Tissue Collection
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
Embryo LacZ: LacZ images wholemount
12 Images
Combined SHIRPA and Dysmorphology
2 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
Eye Morphology: Images Slit Lamp
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Pancreas - hypoplasia Cox4i1tm1.1(KOMP)Vlcg HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cox4i1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Cox4i1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cox4i1tm455699(L1L2_GT1_LF2A_LacZ_BetactP_neo) Targeting vectors

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