Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cenpa by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cenpa.
There are 3 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Epigenetic, genetic and maternal effects enable stable centromere inheritance. | Nature cell biology (May 2022) | Cenpatm1c(EUCOMM)Wtsi | PMC9107508 |
Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation. | Cell metabolism (March 2017) | Cenpatm1c(EUCOMM)Wtsi Cenpatm1a(EUCOMM)Wtsi | PMC5382039 |
Long-Term Retention of CENP-A Nucleosomes in Mammalian Oocytes Underpins Transgenerational Inheritance of Centromere Identity. | Current biology : CB (March 2016) | Cenpatm1c(EUCOMM)Wtsi Cenpatm1a(EUCOMM)Wtsi | PMC4846481 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Cenpatm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Cenpatm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
Cenpatm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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