Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
preweaning lethality, incomplete penetrance | Cdk4tm1b(NCOM)Mfgc | HOM | Early adult | 0.00 | ||
decreased body length | Cdk4tm1b(NCOM)Mfgc | HET | Early adult | 3.32×10-06 | ||
abnormal embryo size | Cdk4tm1b(NCOM)Mfgc | HOM | E15.5 | 0.00 | ||
abnormal cranium morphology | Cdk4tm1b(NCOM)Mfgc | HET | Early adult | 2.69×10-05 | ||
male infertility | Cdk4tm1b(NCOM)Mfgc | HOM | Early adult | 0.00 | ||
abnormal embryo size | Cdk4tm1b(NCOM)Mfgc | HET | E15.5 | 0.00 | ||
female infertility | Cdk4tm1b(NCOM)Mfgc | HOM | Early adult | 0.00 |
Gene: Cdk4
Log in to followExpression
IMPC lacZ Expression Data
Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
---|---|---|---|---|
Axial skeleton | 2 | (1/65) | (2/2) | N/A |
Brain | 5 | (6/506) | (2/11) | N/A |
Central nervous system ganglion | 2 | (1/74) | (2/2) | N/A |
Ear | 5 | (1/506) | (2/11) | N/A |
Embryo | 5 | (1/507) | (2/11) | N/A |
Eye | 5 | (1/506) | (2/11) | N/A |
Foot | 5 | (1/506) | (2/11) | N/A |
Forebrain | 5 | (1/506) | (2/11) | N/A |
Forelimb | 5 | (1/506) | (2/11) | N/A |
Gut | 2 | (1/60) | (2/2) | N/A |
Hand | 5 | (1/506) | (2/11) | N/A |
Head | 5 | (5/506) | (2/11) | N/A |
Heart | 5 | (1/506) | (2/11) | N/A |
Hindbrain | 5 | (6/506) | (2/11) | N/A |
Hindlimb | 5 | (1/506) | (2/11) | N/A |
Liver | 5 | (1/504) | (2/11) | N/A |
Lung | 5 | (1/504) | (2/11) | N/A |
Mandibular process | 5 | (1/506) | (2/11) | N/A |
Maxillary process | 5 | (1/506) | (2/11) | N/A |
Midbrain | 5 | (1/506) | (2/11) | N/A |
Nose | 2 | (1/76) | (2/2) | N/A |
Oral cavity | 5 | (1/504) | (2/11) | N/A |
Skeleton | 2 | (1/76) | (2/2) | N/A |
Skin | 5 | (1/506) | (2/11) | N/A |
Spinal cord | 2 | (1/73) | (2/2) | N/A |
Tail | 5 | (1/506) | (2/11) | N/A |
Tail somite | 5 | (1/506) | (2/11) | N/A |
Trachea | 2 | (1/60) | (2/2) | N/A |
Urinary system | 2 | (1/60) | (2/2) | N/A |
Associated Images
Disease Models
Histopathology
Order Mouse and ES Cells
This service may be affected by the Covid-19 pandemic. See how
MGI Allele | Allele Type | Produced |
---|---|---|
Cdk4tm1b(NCOM)Mfgc | Reporter-tagged deletion allele (post-Cre) | Mice, Tissue |
Cdk4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Cdk4tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Cdk4tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Cdk4tm1a(NCOM)Mfgc | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
The IMPC Newsletter
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter