Cdk4 | cyclin dependent kinase 4

GeneMGI:88357Genome BrowserSynonyms: p34<PSK-J3>/cdk4, Crk3

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Vision/eye Mortality/aging Reproductive system Homeostasis/metabolism Skeleton Embryo Hematopoietic system Craniofacial Growth/size/body region

10 No significant impact

5 Not tested

Gene metrics:12Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Cdk4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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