Cdk4 | cyclin dependent kinase 4
Physiological systems
19 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Embryo Growth/size/body region Vision/eye Hematopoietic system Skeleton Mortality/aging Craniofacial
10 No significant impact
5 Not tested
Gene metrics:11Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues
Human diseases caused by Cdk4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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