Gene: Ccnd2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased spleen weight Ccnd2tm1b(KOMP)Mbp HOM Late adult 7.61×10-09
decreased total body fat amount Ccnd2tm1b(KOMP)Mbp HOM Late adult 3.60×10-06
increased mean corpuscular volume Ccnd2tm1b(KOMP)Mbp HOM Late adult 6.26×10-06
increased bone mineral density Ccnd2tm1b(KOMP)Mbp HOM Late adult 1.80×10-06
increased lean body mass Ccnd2tm1b(KOMP)Mbp HOM Late adult 3.00×10-06
abnormal spine curvature Ccnd2tm1b(KOMP)Mbp HOM Late adult 3.44×10-06
increased bone mineral content Ccnd2tm1b(KOMP)Mbp HOM Late adult 8.41×10-06
increased fasting circulating glucose level Ccnd2tm1b(KOMP)Mbp HOM Early adult 4.74×10-07
abnormal spine curvature Ccnd2tm1b(KOMP)Mbp HOM Early adult 7.84×10-10
decreased body weight Ccnd2tm1b(KOMP)Mbp HOM Late adult 1.62×10-16
abnormal cranium morphology Ccnd2tm1b(KOMP)Mbp HOM Early adult 5.35×10-09
increased circulating iron level Ccnd2tm1b(KOMP)Mbp HOM Late adult 1.44×10-05
hyperactivity Ccnd2tm1b(KOMP)Mbp HOM Early adult 6.13×10-07
increased grip strength Ccnd2tm1b(KOMP)Mbp HOM Late adult 4.56×10-06
impaired glucose tolerance Ccnd2tm1b(KOMP)Mbp HOM Early adult 4.09×10-08
trunk curl Ccnd2tm1b(KOMP)Mbp HOM Middle aged adult 1.01×10-05
small testis Ccnd2tm1b(KOMP)Mbp HOM Late adult 0.00
increased circulating alkaline phosphatase level Ccnd2tm1b(KOMP)Mbp HOM Late adult 1.68×10-08

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (1/2)  Wholemount images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590)  (2/2)  Wholemount images
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (4/4) N/A
Ear 2  (1/506)  (1/4) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506)  (4/4) N/A
Foot 2  (1/506)  (4/4) N/A
Forebrain 2  (1/506)  (4/4) N/A
Forelimb 2  (1/506)  (4/4) N/A
Hand 2  (1/506)  (4/4) N/A
Head 2  (5/506)  (4/4) N/A
Heart 2  (1/506)  (2/4) N/A
Hindbrain 2  (6/506)  (4/4) N/A
Hindlimb 2  (1/506)  (4/4) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/504)  (1/4) N/A
Mandibular process 2  (1/506)  (2/4) N/A
Maxillary process 2  (1/506)  (2/4) N/A
Midbrain 2  (1/506)  (4/4) N/A
Oral cavity 2  (1/504)  (2/4) N/A
Skin 2  (1/506)  (1/4) N/A
Tail 2  (1/506)  (4/4) N/A
Tail somite 2  (1/506)  (3/4) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
4 Images
X-ray: XRay Images Skull Lateral Orientation
1 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
4 Images
Adult LacZ: LacZ Images Wholemount
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ccnd2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Ccnd2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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