Gene: Cbx2

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Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Cbx2tm1b(KOMP)Wtsi HET postnatal 1.20×10-05
preweaning lethality, complete penetrance Cbx2tm1b(KOMP)Wtsi HOM n/a 0.00
persistence of hyaloid vascular system Cbx2tm1b(KOMP)Wtsi HET postnatal 1.24×10-06

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (3/4)  Wholemount images
Aorta 4 No N/A
Bone 4 No N/A
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (4/4)  Wholemount images
Hypothalamus 4 No  (4/4)  Wholemount images
Kidney 4 No  (18/584)  (1/4) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No  (4/4)  Wholemount images
Oral epithelium 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (3/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Striatum 4 No  (4/4)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No N/A
Uterus 4 No N/A
Vascular system 4 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/5) N/A
Ear 2  (1/485)  (2/5) N/A
Embryo 2  (1/485)  (5/5) N/A
Eye 2  (1/485)  (4/5) N/A
Foot 2  (1/485)  (2/5) N/A
Forebrain 2  (1/485)  (4/5) N/A
Forelimb 2  (1/485)  (3/5) N/A
Hand 2  (1/485)  (2/5) N/A
Head 2  (5/485)  (4/5) N/A
Heart 2  (1/485)  (1/5) N/A
Hindbrain 2  (6/485)  (2/5) N/A
Hindlimb 2  (1/485)  (3/5) N/A
Liver 2  (1/485)  (1/5) N/A
Lung 2  (1/485)  (1/5) N/A
Mandibular process 2  (1/485)  (1/5) N/A
Maxillary process 2  (1/485)  (1/5) N/A
Midbrain 2  (1/485)  (4/5) N/A
Oral cavity 2  (1/485)  (1/5) N/A
Skin 2  (1/485)  (1/5) N/A
Tail 2  (1/485)  (1/5) N/A
Tail somite 2  (1/485)  (1/5) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
11 Images
X-ray: XRay Images Dorso Ventral
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cbx2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cbx2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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