Gene: C4b

Name
complement component 4B (Chido blood group)
MGI ID
MGI:88228
Synonyms
Ss C4
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (161) Expression & images (0) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Electrocardiogram (ECG) / RR HOM 13f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00438 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.715 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell X-ray / Number of ribs right HOM 5f:5m 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 14f:7m Fisher Exact Test framework 0.122 Success
C4bem1(IMPC)H MRC Harwell Open Field / Distance travelled - total HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.202 Success
C4bem1(IMPC)H MRC Harwell Electrocardiogram (ECG) / PR HOM 13f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00123 Success
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 1.00 Success
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Open Field / Periphery permanence time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.365 Success
C4bem1(IMPC)H MRC Harwell X-ray / Radius HOM 5f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000194 Success
C4bem1(IMPC)H MRC Harwell Electrocardiogram (ECG) / HR HOM 13f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00468 Success
C4bem1(IMPC)H MRC Harwell X-ray / Fibula HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Percentage center time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.538 Success
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Shape of vertebrae HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Number of center entries HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.269 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Body length HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell X-ray / Brachydactyly HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Pelvis HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.309 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Scapulae HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Shape of spine HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Periphery distance travelled HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.501 Success
C4bem1(IMPC)H MRC Harwell X-ray / Femur HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Center permanence time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.538 Success
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 0.211 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Zygomatic bone HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.508 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 14f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.265 Success
C4bem1(IMPC)H MRC Harwell X-ray / Shape of ribs HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00637 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0103 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 14f:14m Mixed Model framework, generalized least squares, equation withoutWeight 0.238 Success
C4bem1(IMPC)H MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0365 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.703 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Mandibles HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Viability Primary Screen / Outcome HOM 55f:78m Supplied as data Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Humerus HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Center distance travelled HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.201 Success
C4bem1(IMPC)H MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Number of digits HOM 5f:5m 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Clavicle HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Periphery resting time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.111 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Ulna HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Digit integrity HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Teeth HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Number of ribs left HOM 5f:5m 1.00 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.702 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Open Field / Latency to center entry HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0300 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.387 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.276 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Fusion of vertebrae HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell X-ray / Tibia HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Fusion of ribs HOM 5f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 14f:8m Fisher Exact Test framework 0.254 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.464 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00989 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Open Field / Whole arena resting time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.190 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Syndactylism HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Electrocardiogram (ECG) / QTc HOM 13f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0134 Success
C4bem1(IMPC)H MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.229 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Center resting time HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.810 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Open Field / Center average speed HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.651 Success
C4bem1(IMPC)H MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
C4bem1(IMPC)H MRC Harwell X-ray / Joints HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell X-ray / Skull shape HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.497 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 14f:7m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Electrocardiogram (ECG) / QRS HOM 13f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.879 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 14f:9m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.947 Success
C4bem1(IMPC)H MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withWeight 0.861 Success
C4bem1(IMPC)H MRC Harwell Open Field / Periphery average speed HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.164 Success
C4bem1(IMPC)H MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
C4bem1(IMPC)H MRC Harwell X-ray / Processes on vertebrae HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.650 Success
C4bem1(IMPC)H MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
C4bem1(IMPC)H MRC Harwell X-ray / Tibia length HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.977 Success
C4bem1(IMPC)H MRC Harwell Open Field / Whole arena average speed HOM 14f:14m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.202 Success
C4bem1(IMPC)H MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 5f:6m Fisher Exact Test framework 1.00 Success
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 14f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
C4bem1(IMPC)H MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 14f:7m Fisher Exact Test framework 1.00 Success

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
C4btm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
C4bem1(IMPC)H Exon Deletion Mice
C4bem2(IMPC)H Exon Deletion Mice

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