Name
complement component 3
MGI ID
MGI:88227
Synonyms
complement factor 3 acylation stimulating protein Plp
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal motor learning C3tm1.1(KOMP)Vlcg HOM   Early adult 6.69×10-05
decreased circulating glucose level C3tm1.1(KOMP)Vlcg HOM   Early adult 3.27×10-06
decreased circulating triglyceride level C3tm1.1(KOMP)Vlcg HOM   Early adult 4.49×10-05
decreased exploration in new environment C3tm1.1(KOMP)Vlcg HOM Early adult 3.50×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584)  (1/2)  Section images
Aorta 2 No  (1/584) N/A
Brain 2 No  (4/584)  (1/2)  Section images
Brainstem 2 No  (2/584)  (1/2)  Section images
Brown adipose tissue 2 No  (1/2)  Section images
Cartilage tissue 2 No  (1/584) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Epididymis 2 No  (17/133) N/A
Esophagus 2 No  (7/408) N/A
Eye 2 No N/A
Heart 2 No  (2/584) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584)  (1/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584)  (1/2)  Section images
Lymph node 2 No  (1/584) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/584) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No  (2/584) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/584) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/584) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (3/584) N/A
Spleen 2 No  (3/584)  (1/2)  Section images
Stomach 2 No  (12/584) N/A
Striatum 2 No  (3/584) N/A
Submandibular gland 2 No  (2/131)  (1/2)  Section images
Testis 2 No  (6/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/584)  (1/2)  Section images
Thyroid gland 2 No  (16/584) N/A
Trachea 2 No  (3/584) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (1/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/507) N/A
Dorsal root ganglion 1  (1/59) N/A
Ear 1  (1/507) N/A
Embryo 1  (1/508)  (1/1)  Wholemount images
Eye 1  (1/507) N/A
Footplate 1  (1/507) N/A
Forebrain 1  (1/507) N/A
Forelimb 1  (1/507) N/A
Fronto-nasal process 1  (1/60) N/A
Handplate 1  (1/507) N/A
Head 1  (5/507)  (1/1) N/A
Heart 1  (1/507) N/A
Hindbrain 1  (6/507) N/A
Hindlimb 1  (1/507) N/A
Liver 1  (1/502)  (1/1) N/A
Lung 1  (1/502) N/A
Mandibular process 1  (1/507) N/A
Maxillary process 1  (1/507) N/A
Midbrain 1  (1/507) N/A
Nose 1  (1/77) N/A
Oral cavity 1  (1/502) N/A
Skin 1  (1/507) N/A
Spinal cord 1  (1/71) N/A
Tail 1  (1/507) N/A
Tail somite group 1  (1/507) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Original Image
Adult LacZ: LacZ Images Section
12 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Sleep Wake: Wake state (bmp file)
15 Images
Eye Morphology: Images Slit Lamp
2 Images
Combined SHIRPA and Dysmorphology
1 Images
Electroretinography: Rod waveform (pdf format)
4 Images
Electroretinography: Cone waveform (pdf format)
4 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
C3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
C3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
C3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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