Atp1a1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide

GeneMGI:88105Synonyms: Atpa-1

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Muscle Limbs/digits/tail Hematopoietic system Cardiovascular system Mortality/aging

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:17Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
thick ventricular wall2 supporting datasetsAtp1a1em1(IMPC)CcpczheterozygoteEarly adult4.41x10-6 
abnormal digit morphology1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adult4.55x10-7 
decreased heart rate1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adult2.05x10-5 
enlarged heart1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal uterus morphology1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetAtp1a1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetAtp1a1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  
Rows per page: 










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Atp1a1em1(IMPC)CcpczExon Deletionmouse
Atp1a1tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter