Atp1a1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Muscle Limbs/digits/tail Hematopoietic system Cardiovascular system Mortality/aging
12 No significant impact
2 Not tested
Data collections
Gene metrics:17Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal skin morphology | 2 supporting datasets | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
abnormal spleen morphology | 2 supporting datasets | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
abnormal thymus morphology | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
thick ventricular wall | 2 supporting datasets | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | 4.41x10-6 | ||
abnormal digit morphology | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | 4.55x10-7 | ||
decreased heart rate | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | 2.05x10-5 | ||
enlarged heart | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
abnormal uterus morphology | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
enlarged thymus | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Atp1a1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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External links
No external links available for Atp1a1.
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Atp1a1em1(IMPC)Ccpcz | Exon Deletion | | mouse |
Atp1a1tm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |