Atf4 | activating transcription factor 4

GeneMGI:88096Genome BrowserSynonyms: Atf-4, TAXREB67, +2 more

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Mortality/aging Immune system Homeostasis/metabolism Hematopoietic system

18 No significant impact

2 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
51Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Atf4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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