Gene: Atf4

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Name
activating transcription factor 4
MGI ID
MGI:88096
Synonyms
CREB2 Atf-4 TAXREB67 C/ATF
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Atf4tm1.1(KOMP)Mbp HET E9.5 0.00
preweaning lethality, complete penetrance Atf4tm1(KOMP)Mbp HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Atf4tm1.1(KOMP)Mbp HOM E12.5 0.00
embryonic growth retardation Atf4tm1.1(KOMP)Mbp HET E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (1/4) N/A
Aorta 4 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 4 No  (2/4)  Section images
Brainstem 4 No  (2/4) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 4 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 4 No  (4/4)  Section images
Cerebral cortex 4 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 4 No  (7/415)  (4/4) N/A
Eye 4 No  (2/4) N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (2/2) N/A
Heart 4 No  (2/4)  Section images
Hindlimb 2 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No  (2/4) N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 4 No  (18/584)  (4/4) N/A
Large intestine 4 No  (10/584)  (2/4) N/A
Liver 4 No  (2/4)  Section images
Lower urinary tract 4 No  (2/4) N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 4 No  (2/4) N/A
Ovary 4 No  (1/584)  (1/4) N/A
Oviduct 4 No  (1/4) N/A
Pancreas 4 No  (5/584)  (4/4)  Section images
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (2/4) N/A
Prostate gland 4 No  (12/584)  (2/4) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Section images
Small intestine 4 No  (9/584)  (2/4) N/A
Spinal cord 4 No  (3/4)  Section images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4) N/A
Stomach pyloric region 2 No N/A
Striatum 4 No N/A
Sublingual gland 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 4 No  (2/584)  (2/4) N/A
Thymus 4 No  (1/4) N/A
Thyroid gland 4 No  (15/584)  (2/4) N/A
Tongue 2 No  (5/127)  (1/2) N/A
Trachea 4 No  (2/4) N/A
Trigeminal V nerve 2 No  (1/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 4 No  (1/4) N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 4 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 4  (6/504)  (2/5) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 4  (1/504)  (2/5) N/A
Embryo 4  (1/505)  (2/5) N/A
Eye 4  (1/504)  (2/5) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504)  (2/5) N/A
Forelimb 4  (1/504)  (2/5) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 4  (1/503) N/A
Head 4  (5/504) N/A
Heart 4  (1/504)  (2/5) N/A
Hindbrain 4  (6/504)  (2/5) N/A
Hindlimb 4  (1/503)  (2/5) N/A
Liver 4  (1/504)  (2/5) N/A
Lung 4  (1/500) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Midbrain 4  (1/504)  (2/5) N/A
Nose 2  (1/70) N/A
Oral cavity 4  (1/504) N/A
4  (7/37)  (5/5) N/A
Skeleton 2  (1/70) N/A
Skin 4  (1/504)  (2/5) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 4  (1/504)  (2/5) N/A
Tail somite 4  (1/504)  (2/5) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

Adult LacZ: LacZ Images Section
14 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Atf4tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells, Tissue
Atf4tm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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