Name
amyloid beta (A4) precursor protein
MGI ID
MGI:88059
Synonyms
betaAPP Abeta protease nexin II Adap Cvap appican E030013M08Rik
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Apptm1b(KOMP)Wtsi HET Early adult 5.71×10-05
short tibia Apptm1b(KOMP)Wtsi HET Late adult 4.38×10-05
preweaning lethality, incomplete penetrance Apptm1b(KOMP)Wtsi HOM   Early adult 0.00
decreased startle reflex Apptm1b(KOMP)Wtsi HET Late adult 3.58×10-05
increased or absent threshold for auditory brainstem response Apptm1b(KOMP)Wtsi HET Late adult 0.00
increased blood urea nitrogen level Apptm1b(KOMP)Wtsi HET Early adult 7.41×10-07
increased mean corpuscular hemoglobin Apptm1b(KOMP)Wtsi HET   Late adult 1.46×10-06
decreased circulating bilirubin level Apptm1b(KOMP)Wtsi HET Early adult 7.81×10-07

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Immunophenotyping: Panel A FCS file(s)
3 Images
Immunophenotyping: Panel B FCS file(s)
3 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Apptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Apptm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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