Gene: Ampd1

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Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Ampd1tm1b(KOMP)Wtsi HOM Early adult 0.00
preweaning lethality, incomplete penetrance Ampd1tm1b(KOMP)Wtsi HOM   Early adult 0.00
decreased neutrophil cell number Ampd1tm1b(KOMP)Wtsi HET Early adult 5.50×10-05
increased mean platelet volume Ampd1tm1b(KOMP)Wtsi HET Early adult 3.02×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/530) N/A
Aorta 2 No  (1/517) N/A
Brain 2 No  (4/526) N/A
Brainstem 2 No  (2/532) N/A
Cartilage tissue 2 No  (1/538) N/A
Cerebellum 2 No  (3/537) N/A
Cerebral cortex 2 No  (2/535) N/A
Esophagus 2 No  (6/377) N/A
Eye 2 No N/A
Heart 2 No  (2/539) N/A
Hippocampus 2 No  (3/533) N/A
Hypothalamus 2 No  (2/525) N/A
Kidney 2 No  (18/525)  (1/2) N/A
Large intestine 2 No  (9/523)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/528) N/A
Lung 2 No  (1/530) N/A
Lymph node 2 No  (1/531) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/508) N/A
Ovary 2 No  (1/530) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/528) N/A
Peripheral nervous system 2 No  (2/532) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (9/526)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/539) N/A
Small intestine 2 No  (8/524)  (1/2) N/A
Spinal cord 2 No  (2/527) N/A
Spleen 2 No  (3/536) N/A
Stomach 2 No  (12/526) N/A
Striatum 2 No  (2/521) N/A
Testis 2 No  (6/532) N/A
Thymus 2 No  (1/521) N/A
Thyroid gland 2 No  (15/530)  (2/2)  Section images
Trachea 2 No  (3/523) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
18 Images
X-ray: XRay Images Hind Leg and Hip
18 Images
Eye Morphology: Images Slit Lamp
8 Images
Gross Pathology and Tissue Collection
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
18 Images
X-ray: XRay Images Skull Lateral Orientation
18 Images
Adult LacZ: LacZ Images Section
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Eye Morphology: Images Ophthalmoscopy
8 Images

 Disease Models

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 Histopathology

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MGI Allele Allele Type Produced
Ampd1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ampd1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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