Gene: Agtr2

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Name
angiotensin II receptor, type 2
MGI ID
MGI:87966
Synonyms
AT2 receptor
Viability
N/A
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Agtr2tm1a(EUCOMM)Wtsi HOM Early adult 1.14×10-09
decreased circulating alanine transaminase level Agtr2tm1a(EUCOMM)Wtsi HOM Early adult 6.51×10-05
decreased circulating LDL cholesterol level Agtr2tm1a(EUCOMM)Wtsi HOM Early adult 6.12×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584) N/A
Aorta 1 No N/A
Blood vessel 1 No N/A
Bone 1 No N/A
Brain 1 No  (2/2) N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Heart 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No N/A
Lower urinary tract 1 No N/A
Lung 1 No N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Esophagus 1 No N/A
Olfactory lobe 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584) N/A
Parathyroid gland 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Skeletal muscle tissue 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/2) N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Striatum 1 No N/A
Testis 1 No  (2/584) N/A
Thymus 1 No N/A
Thyroid gland 1 No  (15/584) N/A
Trachea 1 No N/A
Uterus 1 No N/A
White adipose tissue 1 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Agtr2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Agtr2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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