Aspa | aspartoacylase
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Hematopoietic system Behavior/neurological
14 No significant impact
5 Not tested
Data collections
Gene metrics:16Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased circulating alkaline phosphatase level | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.73x10-5 | ||
decreased prepulse inhibition | 5 supporting datasets | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.53x10-15 | ||
abnormal cornea morphology | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 2x10-8 | ||
abnormal gait | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.06x10-6 | ||
decreased grip strength | 2 supporting datasets | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.47x10-5 | ||
abnormal lens morphology | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.53x10-5 | ||
increased mean corpuscular volume | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.55x10-5 | ||
increased fasting circulating glucose level | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.06x10-12 | ||
hyperactivity | 2 supporting datasets | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.65x10-8 | ||
decreased startle reflex | 1 supporting dataset | Aspatm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.1x10-6 |
| | | | | | | | | |
External links
No external links available for Aspa.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Aspatm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Aspatm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Aspatm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Aspatm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Aspatm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Aspatm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |