Genes Phenotypes

Gene: Acvr1

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Name
activin A receptor, type 1
MGI ID
MGI:87911
Synonyms
Alk8 Acvr ActR-I SKR1 Tsk7L ActRIA D330013D15Rik ALK2 Acvr1a Alk-2 Acvrlk2
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (88) All data table (151)
Expression & images (103) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Acvr1tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased blood urea nitrogen level Acvr1tm1.1(KOMP)Vlcg HET Early adult 2.47×10-05
embryonic lethality prior to organogenesis Acvr1tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Acvr1tm1.1(KOMP)Vlcg HOM E12.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584)  (1/1)  Section images
Aorta 1 No  (1/1)  Section images
Blood 1 No N/A
Bone marrow 1 No  (1/1)  Section images
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No  (1/1)  Section images
Cartilage tissue 1 No N/A
Cecum 1 No  (12/379)  (1/1)  Section images
Cerebellum 1 No  (1/1)  Section images
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1)  Section images
Diaphragm 1 No  (1/1)  Section images
Duodenum 1 No  (2/127)  (1/1)  Section images
Epididymis 1 No  (18/134)  (1/1)  Section images
Esophagus 1 No  (7/415)  (1/1)  Section images
Eye 1 No  (1/1)  Section images
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1)  Section images
Harderian gland 1 No  (1/1)  Section images
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127)  (1/1)  Section images
Jejunum 1 No  (6/127)  (1/1)  Section images
Kidney 1 No  (18/584)  (1/1)  Section images
Large intestine 1 No  (10/584) N/A
Liver 1 No  (1/1)  Section images
Lower urinary tract 1 No N/A
Lung 1 No  (1/1)  Section images
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No  (1/1)  Section images
Mesenteric lymph node 1 No  (1/1)  Section images
Midbrain 1 No  (1/1)  Section images
Olfactory lobe 1 No  (1/1)  Section images
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/1)  Section images
Parathyroid gland 1 No N/A
Parotid gland 1 No  (1/1)  Section images
Penis 1 No  (1/1)  Section images
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/1)  Section images
Prostate gland 1 No  (12/584)  (1/1)  Section images
Quadriceps 1 No  (1/1)  Section images
Sciatic nerve 1 No  (1/1)  Section images
Skeletal muscle 1 No N/A
Skin 1 No  (1/1)  Section images
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/1)  Section images
Spleen 1 No  (2/584)  (1/1)  Section images
Stomach 1 No  (12/584)  (1/1)  Section images
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No  (1/1)  Section images
Submandibular gland 1 No  (2/132)  (1/1)  Section images
Testis 1 No  (2/584)  (1/1)  Section images
Thymus 1 No  (1/1)  Section images
Thyroid gland 1 No  (15/584)  (1/1)  Section images
Tongue 1 No  (5/127)  (1/1)  Section images
Trachea 1 No  (1/1)  Section images
Trigeminal V nerve 1 No  (1/1)  Section images
Urinary bladder 1 No  (1/1)  Section images
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1)  Section images
Vascular system 1 No N/A
Vesicular gland 1 No  (1/1)  Section images
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (17)
adipose tissue (5)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
digestive system (25)
Cecum expression
MA:0000334
endocrine system (4)
Adrenal gland expression
MA:0000116
exocrine system (9)
Parotid gland expression
MA:0001585
immune system (9)
Bone Marrow expression
MA:0000134
integumental system (3)
Skin expression
MA:0000151
limb (2)
Sciatic nerve expression
MA:0001172
musculoskeletal system (7)
Bone Marrow expression
MA:0000134
nervous system (12)
Cerebellum expression
MA:0000198
postnatal mouse (97)
Adrenal gland expression
MA:0000116
reproductive system (15)
Epididymis expression
MA:0000397
respiratory system (14)
Diaphragm expression
MA:0001904
sensory organ (8)
Eye expression
MA:0000261
set of connective tissues (5)
Brown adipose tissue expression
MA:0000057
trunk (54)
Adrenal gland expression
MA:0000116
urinary system (6)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 7  (6/504)  (2/7) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 7  (1/504)  (2/7) N/A
Embryo 7  (1/505)  (2/7) N/A
Eye 7  (1/504)  (2/7) N/A
Foot 7  (1/504)  (2/7) N/A
Forebrain 7  (1/504)  (2/7) N/A
Forelimb 7  (1/504)  (2/7) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 7  (1/503)  (2/7) N/A
Head 7  (5/504)  (2/7) N/A
Heart 7  (1/504)  (2/7) N/A
Hindbrain 7  (6/504)  (2/7) N/A
Hindlimb 7  (1/503)  (2/7) N/A
Liver 7  (1/504)  (2/7) N/A
Lung 7  (1/500)  (2/7) N/A
Mandibular process 7  (1/504)  (2/7) N/A
Maxillary process 7  (1/504)  (2/7) N/A
Midbrain 7  (1/504)  (2/7) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 7  (1/504)  (2/7) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 7  (1/504)  (2/7) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 7  (1/504)  (2/7) N/A
Tail somite 7  (1/504)  (2/7) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
40 Images
Embryo LacZ: LacZ images wholemount
28 Images
Adult LacZ: LacZ Images Section
114 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Acvr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Acvr1tm27043(L1L2_gt1) Targeting vectors

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