Gene: Acvr1

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Name
activin A receptor, type 1
MGI ID
MGI:87911
Synonyms
ActR-I ALK2 Acvr Acvrlk2 ActRIA Tsk7L SKR1 D330013D15Rik Alk8 Alk-2 Acvr1a
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Acvr1tm1.1(KOMP)Vlcg HOM E12.5 0.00
embryonic lethality prior to organogenesis Acvr1tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased blood urea nitrogen level Acvr1tm1.1(KOMP)Vlcg HET Early adult 3.97×10-06
preweaning lethality, complete penetrance Acvr1tm1.1(KOMP)Vlcg HOM Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
1 No  (3/590)  (1/1)  Section images
1 No  (1/590)  (1/1)  Section images
1 No N/A
1 No  (1/1)  Section images
1 No  (3/590) N/A
1 No  (2/590) N/A
1 No  (1/1)  Section images
1 No N/A
1 No  (12/377)  (1/1)  Section images
1 No  (3/590)  (1/1)  Section images
1 No  (2/590) N/A
1 No N/A
1 No  (12/127)  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (2/127)  (1/1)  Section images
1 No  (18/134)  (1/1)  Section images
1 No  (7/415)  (1/1)  Section images
1 No  (1/1)  Section images
1 No N/A
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (1/590) N/A
1 No N/A
1 No  (3/590) N/A
1 No  (2/590) N/A
1 No  (14/127)  (1/1)  Section images
1 No  (6/127)  (1/1)  Section images
1 No  (20/590)  (1/1)  Section images
1 No  (10/590) N/A
1 No  (1/1)  Section images
1 No  (1/590) N/A
1 No  (1/590)  (1/1)  Section images
1 No N/A
1 No N/A
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (2/590)  (1/1)  Section images
1 No  (1/590) N/A
1 No N/A
1 No  (5/590)  (1/1)  Section images
1 No N/A
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (1/590) N/A
1 No N/A
1 No  (1/590)  (1/1)  Section images
1 No  (12/590)  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No N/A
1 No  (1/1)  Section images
1 No  (9/590) N/A
1 No  (2/590)  (1/1)  Section images
1 No  (2/590)  (1/1)  Section images
1 No  (13/590)  (1/1)  Section images
1 No N/A
1 No  (3/590) N/A
1 No  (1/1)  Section images
1 No  (2/132)  (1/1)  Section images
1 No  (5/590)  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (16/590)  (1/1)  Section images
1 No  (5/127)  (1/1)  Section images
1 No  (2/590)  (1/1)  Section images
1 No  (1/1)  Section images
1 No  (1/1)  Section images
1 No N/A
1 No N/A
1 No  (15/388)  (1/1)  Section images
1 No N/A
1 No  (1/1)  Section images
1 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/65)  (2/2) N/A
7  (6/506)  (2/7) N/A
2  (1/74)  (2/2) N/A
7  (1/506)  (2/7) N/A
7  (1/507)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
2  (1/60)  (2/2) N/A
7  (1/506)  (2/7) N/A
7  (5/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (6/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/504)  (2/7) N/A
7  (1/504)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
2  (1/76)  (2/2) N/A
7  (1/504)  (2/7) N/A
2  (7/39)  (2/2) N/A
2  (1/76)  (2/2) N/A
7  (1/506)  (2/7) N/A
2  (1/73)  (2/2) N/A
7  (1/506)  (2/7) N/A
7  (1/506)  (2/7) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
114 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
Embryo LacZ: LacZ images wholemount
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acvr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Acvr1tm27043(L1L2_gt1) Targeting vectors
Acvr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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