Genes Phenotypes

Gene: Acvr1

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Name
activin A receptor, type 1
MGI ID
MGI:87911
Synonyms
Alk8 SKR1 Acvr ActR-I D330013D15Rik Acvrlk2 ALK2 Tsk7L Acvr1a ActRIA Alk-2
Viability
N/A
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (165) All data table (226)
Expression & images (103) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Acvr1tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
decreased blood urea nitrogen level Acvr1tm1.1(KOMP)Vlcg HET postnatal 2.50×10-05
embryonic lethality prior to organogenesis Acvr1tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584)  (1/1) N/A
Aorta 1 No  (1/1) N/A
Blood 1 No N/A
Bone marrow 1 No  (1/1) N/A
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No  (1/1) N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/383)  (1/1) N/A
Cerebellum 1 No  (1/1) N/A
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1) N/A
Diaphragm 1 No  (1/1) N/A
Duodenum 1 No  (2/127)  (1/1) N/A
Epididymis 1 No  (18/134)  (1/1) N/A
Esophagus 1 No  (7/415)  (1/1) N/A
Eye 1 No  (1/1) N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1) N/A
Harderian gland 1 No  (1/1) N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127)  (1/1) N/A
Jejunum 1 No  (6/127)  (1/1) N/A
Kidney 1 No  (18/584)  (1/1) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No  (1/1) N/A
Lower urinary tract 1 No N/A
Lung 1 No  (1/1) N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No  (1/1) N/A
Mesenteric lymph node 1 No  (1/1) N/A
Midbrain 1 No  (1/1) N/A
Olfactory lobe 1 No  (1/1) N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/1) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No  (1/1) N/A
Penis 1 No  (1/1) N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/1) N/A
Prostate gland 1 No  (12/584)  (1/1) N/A
Quadriceps 1 No  (1/1) N/A
Sciatic nerve 1 No  (1/1) N/A
Skeletal muscle 1 No N/A
Skin 1 No  (1/1) N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/1) N/A
Spleen 1 No  (2/584)  (1/1) N/A
Stomach 1 No  (12/584)  (1/1) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No  (1/1) N/A
Submandibular gland 1 No  (2/132)  (1/1) N/A
Testis 1 No  (2/584)  (1/1) N/A
Thymus 1 No  (1/1) N/A
Thyroid gland 1 No  (15/584)  (1/1) N/A
Tongue 1 No  (5/127)  (1/1) N/A
Trachea 1 No  (1/1) N/A
Trigeminal V nerve 1 No  (1/1) N/A
Urinary bladder 1 No  (1/1) N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1) N/A
Vascular system 1 No N/A
Vesicular gland 1 No  (1/1) N/A
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 7  (6/485)  (2/7) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 7  (1/485)  (2/7) N/A
Embryo 7  (1/485)  (2/7) N/A
Eye 7  (1/485)  (2/7) N/A
Foot 7  (1/485)  (2/7) N/A
Forebrain 7  (1/485)  (2/7) N/A
Forelimb 7  (1/485)  (2/7) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 7  (1/485)  (2/7) N/A
Head 7  (5/485)  (2/7) N/A
Heart 7  (1/485)  (2/7) N/A
Hindbrain 7  (6/485)  (2/7) N/A
Hindlimb 7  (1/485)  (2/7) N/A
Liver 7  (1/485)  (2/7) N/A
Lung 7  (1/485)  (2/7) N/A
Mandibular process 7  (1/485)  (2/7) N/A
Maxillary process 7  (1/485)  (2/7) N/A
Midbrain 7  (1/485)  (2/7) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 7  (1/485)  (2/7) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 7  (1/485)  (2/7) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 7  (1/485)  (2/7) N/A
Tail somite 7  (1/485)  (2/7) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images
Embryo LacZ: LacZ images wholemount
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Acvr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Acvr1tm27043(L1L2_gt1) Targeting vectors
Acvr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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