Gene: Acvr1

Name
activin A receptor, type 1
MGI ID
MGI:87911
Synonyms
Alk8 SKR1 Acvr ActR-I D330013D15Rik Acvrlk2 ALK2 Tsk7L Acvr1a ActRIA Alk-2
Viability
N/A
View
N/A
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Acvr1tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
embryonic lethality prior to organogenesis Acvr1tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
decreased blood urea nitrogen level Acvr1tm1.1(KOMP)Vlcg HET postnatal 2.50×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584)  (1/1) N/A
Aorta 1 No  (1/1) N/A
Blood 1 No N/A
Bone marrow 1 No  (1/1) N/A
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No  (1/1) N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/383)  (1/1) N/A
Cerebellum 1 No  (1/1) N/A
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1) N/A
Diaphragm 1 No  (1/1) N/A
Duodenum 1 No  (2/127)  (1/1) N/A
Epididymis 1 No  (18/134)  (1/1) N/A
Esophagus 1 No  (7/415)  (1/1) N/A
Eye 1 No  (1/1) N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1) N/A
Harderian gland 1 No  (1/1) N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127)  (1/1) N/A
Jejunum 1 No  (6/127)  (1/1) N/A
Kidney 1 No  (18/584)  (1/1) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No  (1/1) N/A
Lower urinary tract 1 No N/A
Lung 1 No  (1/1) N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No  (1/1) N/A
Mesenteric lymph node 1 No  (1/1) N/A
Midbrain 1 No  (1/1) N/A
Olfactory lobe 1 No  (1/1) N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/1) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No  (1/1) N/A
Penis 1 No  (1/1) N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/1) N/A
Prostate gland 1 No  (12/584)  (1/1) N/A
Quadriceps 1 No  (1/1) N/A
Sciatic nerve 1 No  (1/1) N/A
Skeletal muscle 1 No N/A
Skin 1 No  (1/1) N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/1) N/A
Spleen 1 No  (2/584)  (1/1) N/A
Stomach 1 No  (12/584)  (1/1) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No  (1/1) N/A
Submandibular gland 1 No  (2/132)  (1/1) N/A
Testis 1 No  (2/584)  (1/1) N/A
Thymus 1 No  (1/1) N/A
Thyroid gland 1 No  (15/584)  (1/1) N/A
Tongue 1 No  (5/127)  (1/1) N/A
Trachea 1 No  (1/1) N/A
Trigeminal V nerve 1 No  (1/1) N/A
Urinary bladder 1 No  (1/1) N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1) N/A
Vascular system 1 No N/A
Vesicular gland 1 No  (1/1) N/A
White adipose tissue 1 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 7  (6/485)  (2/7) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 7  (1/485)  (2/7) N/A
Embryo 7  (1/485)  (2/7) N/A
Eye 7  (1/485)  (2/7) N/A
Foot 7  (1/485)  (2/7) N/A
Forebrain 7  (1/485)  (2/7) N/A
Forelimb 7  (1/485)  (2/7) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 7  (1/485)  (2/7) N/A
Head 7  (5/485)  (2/7) N/A
Heart 7  (1/485)  (2/7) N/A
Hindbrain 7  (6/485)  (2/7) N/A
Hindlimb 7  (1/485)  (2/7) N/A
Liver 7  (1/485)  (2/7) N/A
Lung 7  (1/485)  (2/7) N/A
Mandibular process 7  (1/485)  (2/7) N/A
Maxillary process 7  (1/485)  (2/7) N/A
Midbrain 7  (1/485)  (2/7) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 7  (1/485)  (2/7) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 7  (1/485)  (2/7) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 7  (1/485)  (2/7) N/A
Tail somite 7  (1/485)  (2/7) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images
Embryo LacZ: LacZ images wholemount
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Acvr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Acvr1tm27043(L1L2_gt1) Targeting vectors
Acvr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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