Genes Phenotypes

Gene: Acvr1

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Name
activin A receptor, type 1
MGI ID
MGI:87911
Synonyms
Alk8 Acvr ActR-I SKR1 Tsk7L ActRIA D330013D15Rik ALK2 Acvr1a Alk-2 Acvrlk2
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (88) All data table (311)
Expression & images (103) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Acvr1tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased blood urea nitrogen level Acvr1tm1.1(KOMP)Vlcg HET Early adult 2.47×10-05
embryonic lethality prior to organogenesis Acvr1tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Acvr1tm1.1(KOMP)Vlcg HOM E12.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584)  (1/1)  Section images
Aorta 1 No  (1/1)  Section images
Blood 1 No N/A
Bone marrow 1 No  (1/1)  Section images
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No  (1/1)  Section images
Cartilage tissue 1 No N/A
Cecum 1 No  (12/379)  (1/1)  Section images
Cerebellum 1 No  (1/1)  Section images
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1)  Section images
Diaphragm 1 No  (1/1)  Section images
Duodenum 1 No  (2/127)  (1/1)  Section images
Epididymis 1 No  (18/134)  (1/1)  Section images
Esophagus 1 No  (7/415)  (1/1)  Section images
Eye 1 No  (1/1)  Section images
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1)  Section images
Harderian gland 1 No  (1/1)  Section images
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127)  (1/1)  Section images
Jejunum 1 No  (6/127)  (1/1)  Section images
Kidney 1 No  (18/584)  (1/1)  Section images
Large intestine 1 No  (10/584) N/A
Liver 1 No  (1/1)  Section images
Lower urinary tract 1 No N/A
Lung 1 No  (1/1)  Section images
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No  (1/1)  Section images
Mesenteric lymph node 1 No  (1/1)  Section images
Midbrain 1 No  (1/1)  Section images
Olfactory lobe 1 No  (1/1)  Section images
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/1)  Section images
Parathyroid gland 1 No N/A
Parotid gland 1 No  (1/1)  Section images
Penis 1 No  (1/1)  Section images
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/1)  Section images
Prostate gland 1 No  (12/584)  (1/1)  Section images
Quadriceps 1 No  (1/1)  Section images
Sciatic nerve 1 No  (1/1)  Section images
Skeletal muscle 1 No N/A
Skin 1 No  (1/1)  Section images
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/1)  Section images
Spleen 1 No  (2/584)  (1/1)  Section images
Stomach 1 No  (12/584)  (1/1)  Section images
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No  (1/1)  Section images
Submandibular gland 1 No  (2/132)  (1/1)  Section images
Testis 1 No  (2/584)  (1/1)  Section images
Thymus 1 No  (1/1)  Section images
Thyroid gland 1 No  (15/584)  (1/1)  Section images
Tongue 1 No  (5/127)  (1/1)  Section images
Trachea 1 No  (1/1)  Section images
Trigeminal V nerve 1 No  (1/1)  Section images
Urinary bladder 1 No  (1/1)  Section images
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1)  Section images
Vascular system 1 No N/A
Vesicular gland 1 No  (1/1)  Section images
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (17)
adipose tissue (5)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
digestive system (25)
Cecum expression
MA:0000334
endocrine system (4)
Adrenal gland expression
MA:0000116
exocrine system (9)
Parotid gland expression
MA:0001585
immune system (9)
Bone Marrow expression
MA:0000134
integumental system (3)
Skin expression
MA:0000151
limb (2)
Sciatic nerve expression
MA:0001172
musculoskeletal system (7)
Bone Marrow expression
MA:0000134
nervous system (12)
Cerebellum expression
MA:0000198
postnatal mouse (97)
Adrenal gland expression
MA:0000116
reproductive system (15)
Epididymis expression
MA:0000397
respiratory system (14)
Diaphragm expression
MA:0001904
sensory organ (8)
Eye expression
MA:0000261
set of connective tissues (5)
Brown adipose tissue expression
MA:0000057
trunk (54)
Adrenal gland expression
MA:0000116
urinary system (6)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 7  (6/504)  (2/7) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 7  (1/504)  (2/7) N/A
Embryo 7  (1/505)  (2/7) N/A
Eye 7  (1/504)  (2/7) N/A
Foot 7  (1/504)  (2/7) N/A
Forebrain 7  (1/504)  (2/7) N/A
Forelimb 7  (1/504)  (2/7) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 7  (1/503)  (2/7) N/A
Head 7  (5/504)  (2/7) N/A
Heart 7  (1/504)  (2/7) N/A
Hindbrain 7  (6/504)  (2/7) N/A
Hindlimb 7  (1/503)  (2/7) N/A
Liver 7  (1/504)  (2/7) N/A
Lung 7  (1/500)  (2/7) N/A
Mandibular process 7  (1/504)  (2/7) N/A
Maxillary process 7  (1/504)  (2/7) N/A
Midbrain 7  (1/504)  (2/7) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 7  (1/504)  (2/7) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 7  (1/504)  (2/7) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 7  (1/504)  (2/7) N/A
Tail somite 7  (1/504)  (2/7) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
28 Images
Adult LacZ: LacZ Images Section
114 Images
X-ray: XRay Images Whole Body Dorso Ventral
40 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acvr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Acvr1tm27043(L1L2_gt1) Targeting vectors

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