Gene Summary

Name:
actin, gamma, cytoplasmic 1
Synonyms:
Actl,  E51

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
pallor Actg1tm1.1(KOMP)Vlcg HOM E12.5 0.00
preweaning lethality, incomplete penetrance Actg1tm1.1(KOMP)Vlcg HOM   Early adult 0.00
embryonic growth retardation Actg1tm1.1(KOMP)Vlcg HOM E12.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
Adrenal gland  Section images heterozygote 50% (1 of 2)
Aorta  Section images heterozygote 100% (2 of 2)
Blood  Section images heterozygote 100% (2 of 2)
Bone marrow  Section images heterozygote 100% (2 of 2)
Brown adipose tissue  Section images heterozygote 50% (1 of 2)
Cecum  Section images heterozygote 100% (2 of 2)
Cerebellum  Section images heterozygote 100% (2 of 2)
Colon  Section images heterozygote 100% (2 of 2)
Diaphragm  Section images heterozygote 100% (2 of 2)
Duodenum  Section images heterozygote 50% (1 of 2)
Epididymis  Section images heterozygote 50% (1 of 2)
Esophagus  Section images heterozygote 100% (2 of 2)
Eye  Section images heterozygote 50% (1 of 2)
Gonadal fat pad  Section images heterozygote 50% (1 of 2)
Harderian gland  Section images heterozygote 100% (2 of 2)
Ileum  Section images heterozygote 100% (2 of 2)
Jejunum  Section images heterozygote 100% (2 of 2)
Kidney  Section images heterozygote 100% (2 of 2)
Liver  Section images heterozygote 50% (1 of 2)
Lung  Section images heterozygote 100% (2 of 2)
Mammary gland  Section images heterozygote 50% (1 of 2)
Mesenteric adipose tissue  Section images heterozygote 50% (1 of 2)
Mesenteric lymph node  Section images heterozygote 50% (1 of 2)
Midbrain  Section images heterozygote 100% (2 of 2)
Olfactory lobe  Section images heterozygote 50% (1 of 2)
Ovary  Section images heterozygote 50% (1 of 2)
Pancreas  Section images heterozygote 50% (1 of 2)
Parathyroid gland  Section images heterozygote 50% (1 of 2)
Parotid gland  Section images heterozygote 50% (1 of 2)
Penis  Section images heterozygote 50% (1 of 2)
Pituitary gland  Section images heterozygote 50% (1 of 2)
Prostate gland  Section images heterozygote 50% (1 of 2)
Quadriceps  Section images heterozygote 100% (2 of 2)
Sciatic nerve  Section images heterozygote 50% (1 of 2)
Skin  Section images heterozygote 100% (2 of 2)
Spinal cord  Section images heterozygote 100% (2 of 2)
Spleen  Section images heterozygote 100% (2 of 2)
Stomach  Section images heterozygote 100% (2 of 2)
Sublingual gland  Section images heterozygote 100% (2 of 2)
Submandibular gland  Section images heterozygote 100% (2 of 2)
Testis  Section images heterozygote 50% (1 of 2)
Thymus  Section images heterozygote 100% (2 of 2)
Thyroid gland  Section images heterozygote 50% (1 of 2)
Tongue  Section images heterozygote 100% (2 of 2)
Trachea  Section images heterozygote 50% (1 of 2)
Trigeminal V nerve  Section images heterozygote 100% (2 of 2)
Urinary bladder  Section images heterozygote 100% (2 of 2)
Uterus  Section images heterozygote 50% (1 of 2)
Vas deferens  Section images heterozygote 50% (1 of 2)
Vesicular gland  Section images heterozygote 50% (1 of 2)
Brain N/A heterozygote 100% (2 of 2)
Brainstem N/A heterozygote Not available
Cartilage tissue N/A heterozygote Not available
Cerebral cortex N/A heterozygote Not available
Chest bone N/A heterozygote Not available
Gall bladder N/A heterozygote Not available
Heart N/A heterozygote Not available
Hindlimb N/A heterozygote Not available
Hippocampus N/A heterozygote Not available
Hypothalamus N/A heterozygote Not available
Large intestine N/A heterozygote 100% (2 of 2)
Lower urinary tract N/A heterozygote Not available
Lymph node N/A heterozygote Not available
Oviduct N/A heterozygote 0.0% (0 of 2)
Peripheral nervous system N/A heterozygote Not available
Peyer's patch N/A heterozygote Not available
Skeletal muscle N/A heterozygote Not available
Small intestine N/A heterozygote 100% (2 of 2)
Stomach pyloric region N/A heterozygote Not available
Striatum N/A heterozygote Not available
Vagina N/A heterozygote Not available
Vascular system N/A heterozygote Not available
White adipose tissue N/A heterozygote Not available
No Embryo expression data was found for this gene.

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)
adrenal gland 0.67% (4 of 598)
aorta 0.17% (1 of 598)
blood 0.0%
bone marrow 0.0%
brain 0.84% (5 of 598)
brainstem 0.33% (2 of 598)
brown adipose tissue 0.0%
cartilage tissue 0.17% (1 of 598)
cecum 5.73% (22 of 384)
cerebellum 0.5% (3 of 598)
cerebral cortex 0.33% (2 of 598)
chest bone Unavailable
colon 15.71% (22 of 140)
diaphragm 0.0%
duodenum 3.57% (5 of 140)
epididymis 14.29% (21 of 147)
esophagus 1.66% (7 of 422)
eye 0.0%
gall bladder 0.0%
gonadal fat pad 0.0%
harderian gland 0.71% (1 of 140)
heart 0.33% (2 of 598)
hindlimb 0.0%
hippocampus 0.5% (3 of 598)
hypothalamus 0.33% (2 of 598)
ileum 14.29% (20 of 140)
jejunum 8.57% (12 of 140)
kidney 4.52% (27 of 598)
large intestine 5.35% (32 of 598)
liver 0.0%
lower urinary tract 0.17% (1 of 598)
lung 0.33% (2 of 598)
lymph node 0.17% (1 of 598)
mammary gland 0.0%
mesenteric adipose tissue 0.0%
mesenteric lymph node 0.31% (1 of 323)
midbrain 0.0%
olfactory lobe 0.33% (2 of 598)
ovary 0.17% (1 of 598)
oviduct 0.0%
pancreas 0.84% (5 of 598)
parathyroid gland 0.17% (1 of 576)
parotid gland 0.0%
penis 0.0%
peripheral nervous system 0.33% (2 of 598)
peyers patch 0.0%
pituitary gland 0.17% (1 of 598)
prostate gland 2.17% (13 of 598)
quadriceps 0.0%
sciatic nerve 0.0%
skeletal muscle 0.0%
skin 0.17% (1 of 598)
small intestine 5.35% (32 of 598)
spinal cord 0.5% (3 of 598)
spleen 0.5% (3 of 598)
stomach 3.68% (22 of 598)
stomach pyloric region 0.0%
striatum 0.5% (3 of 598)
sublingual gland 0.0%
submandibular gland 1.38% (2 of 145)
testis 1% (6 of 598)
thymus 0.17% (1 of 598)
thyroid gland 3.01% (18 of 598)
tongue 3.57% (5 of 140)
trachea 0.5% (3 of 598)
trigeminal v nerve 0.0%
urinary bladder 0.0%
uterus 0.33% (2 of 598)
vagina 0.0%
vas deferens 4.56% (18 of 395)
vascular system 0.0%
vesicular gland 0.0%
white adipose tissue 0.0%
No Embryo expression data was found for this gene.

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Adult LacZ

LacZ Images Section

141 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

MicroCT E14.5-E15.5

Embryo reconstruction

8 Images

Human diseases caused by Actg1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Actg1 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Deafness, Autosomal Dominant 20
Bilateral sensorineural hearing impairment, Progressive sensorineural hearing impairment OMIM:604717
Baraitser-Winter Syndrome 2
Hearing impairment, Abnormal pinna morphology OMIM:614583
Baraitser-Winter Cerebrofrontofacial Syndrome
Failure to thrive, Optic disc coloboma ORPHA:2995

The table below shows human diseases predicted to be associated to Actg1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Retinitis Pigmentosa 81
Pallor OMIM:617871
Retinitis Pigmentosa 42
Pallor OMIM:612943
Auditory Neuropathy, Autosomal Dominant 1
Sensorineural hearing impairment, Abnormal speech discrimination, Absence of acoustic reflex, Abn... OMIM:609129
Deafness, Autosomal Recessive 9
Sensorineural hearing impairment, Absent brainstem auditory responses, Absence of acoustic reflex OMIM:601071
Deafness, Autosomal Recessive 104
Absent brainstem auditory responses, Prelingual sensorineural hearing impairment, Vestibular dysf... OMIM:616515
Retinitis Pigmentosa 60
Pallor OMIM:613983
Optic Atrophy 9
Pallor OMIM:616289
Ravine Syndrome
Failure to thrive, Decreased body weight, Abnormal auditory evoked potentials ORPHA:99852
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome
Pallor ORPHA:46532
Breath-Holding Spells
Pallor OMIM:607578
Abcd Syndrome
Neonatal death, Large for gestational age, Abnormal auditory evoked potentials, Total intestinal ... OMIM:600501
Retinitis Pigmentosa 70
Pallor OMIM:615922
Deafness, Autosomal Dominant 20
Bilateral sensorineural hearing impairment, Progressive sensorineural hearing impairment OMIM:604717
Cone-Rod Dystrophy 11
Pallor OMIM:610381
Methylmalonic Acidemia With Homocystinuria, Type Cbld
Pallor ORPHA:79283
Charcot-Marie-Tooth Disease, Type 4B1
Decreased motor nerve conduction velocity, Abnormal auditory evoked potentials, Facial palsy OMIM:601382
Peripheral Cone Dystrophy
Pallor OMIM:609021
Retinitis Pigmentosa 73
Pallor OMIM:616544
Auditory Neuropathy And Optic Atrophy
Pallor OMIM:617717
Optic Atrophy 8
Sensorineural hearing impairment, Optic atrophy, Prolonged somatosensory evoked potentials, Abnor... OMIM:616648
Retinohepatoendocrinologic Syndrome
Pallor OMIM:268040
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome
Pallor, Short stature ORPHA:2786
Autoimmune Hemolytic Anemia, Cold Type
Pallor ORPHA:228312
Non-Syndromic Genetic Deafness
Postlingual sensorineural hearing impairment, Conductive hearing impairment, High-frequency heari... ORPHA:87884
Benign Paroxysmal Torticollis Of Infancy
Pallor ORPHA:71518
Autosomal Recessive Spastic Paraplegia Type 44
Sensorineural hearing impairment, Abnormality of somatosensory evoked potentials, Abnormal motor ... ORPHA:320401
Dermatitis, Atopic
Pallor, Dry skin, Facial erythema OMIM:603165
Retinitis Pigmentosa 27
Pallor OMIM:613750
Anemia, Hypochromic Microcytic, With Iron Overload 2
Pallor, Growth delay OMIM:615234
Charcot-Marie-Tooth Disease, Type 4D
Hearing impairment, Decreased nerve conduction velocity, Abnormal auditory evoked potentials OMIM:601455
Optic Atrophy 1
Pallor OMIM:165500
Acute Peripheral Arterial Occlusion
Pallor ORPHA:90064
Acute Myelomonocytic Leukemia
Pallor ORPHA:517
Neurodevelopmental Disorder With Hypotonia, Neuropathy, And Deafness
Sensorineural hearing impairment, Absent brainstem auditory responses, Facial palsy, EEG abnormality OMIM:617519
Leber Congenital Amaurosis 14
Pallor OMIM:613341
Primary Lateral Sclerosis, Juvenile
Pallor OMIM:606353
Optic Atrophy With Or Without Deafness, Ophthalmoplegia, Myopathy, Ataxia, And Neuropathy
Abnormal auditory evoked potentials, Optic atrophy, Progressive sensorineural hearing impairment OMIM:125250
Myelofibrosis
Pallor, Purpura OMIM:254450
Anemia, Congenital Dyserythropoietic, Type Ib
Pallor, Growth delay, Short stature OMIM:615631
X-Linked Sideroblastic Anemia
Pallor ORPHA:75563
Optic Atrophy 7 With Or Without Auditory Neuropathy
Pallor OMIM:612989
Hemoglobin D Disease
Pallor ORPHA:90039
Myoclonus, Intractable, Neonatal
Pallor OMIM:617235
Charcot-Marie-Tooth Disease, Type 4C
Decreased motor nerve conduction velocity, Facial palsy, Abnormal cranial nerve morphology, Heari... OMIM:601596
Retinitis Pigmentosa 75
Pallor OMIM:617023
Cyclic Vomiting Syndrome
Pallor, Growth delay OMIM:500007
Thiamine-Responsive Megaloblastic Anemia Syndrome
Pallor, Short stature ORPHA:49827
Irida Syndrome
Pallor ORPHA:209981
Muscular Dystrophy, Limb-Girdle, Autosomal Dominant 2
Pallor OMIM:608423
Familial Focal Epilepsy With Variable Foci
Pallor ORPHA:98820
Mohr-Tranebjaerg Syndrome
Sensorineural hearing impairment, Absent brainstem auditory responses, Postlingual sensorineural ... ORPHA:52368
Elliptocytosis 1
Pallor OMIM:611804
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Pallor ORPHA:276608
Anemia, Sideroblastic, 1
Anemic pallor OMIM:300751
Retinitis Pigmentosa 51
Pallor OMIM:613464
Autosomal Dominant Optic Atrophy Plus Syndrome
Sensorineural hearing impairment, Absent brainstem auditory responses, Temporal optic disc pallor... ORPHA:1215
Spontaneous Periodic Hypothermia
Pallor ORPHA:29822
Acrocraniofacial Dysostosis
Sensorineural hearing impairment, Abnormality of the outer ear, Conductive hearing impairment, Ab... OMIM:201050
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1
Pallor, Delayed puberty OMIM:600462
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency
Pallor OMIM:613839
Evans Syndrome
Pallor, Petechiae ORPHA:1959
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia
Pallor, Short stature OMIM:611590
Pyruvate Kinase Deficiency Of Red Cells
Pallor, Intrauterine growth retardation OMIM:266200
Axenfeld-Rieger Anomaly With Partially Absent Eye Muscles, Distinctive Face, Hydrocephaly, And Skeletal Abnormalities
Sensorineural hearing impairment, Abnormal auditory evoked potentials OMIM:109120
Hyperinsulinism Due To Ucp2 Deficiency
Pallor ORPHA:276556
Beta-Thalassemia
Skin ulcer, Pallor ORPHA:848
Drug-Induced Autoimmune Hemolytic Anemia
Pallor ORPHA:90037
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Pallor ORPHA:276575
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Pallor ORPHA:276580
Hb Bart'S Hydrops Fetalis
Pallor ORPHA:163596
Hyperinsulinism Due To Hnf1A Deficiency
Pallor ORPHA:324575
Leishmaniasis
Skin ulcer, Pallor ORPHA:507
Cold Agglutinin Disease
Pallor ORPHA:56425
Kcnq2-Related Epileptic Encephalopathy
Facial erythema, Pallor ORPHA:439218
Fanconi Anemia, Complementation Group I
Pallor, Intrauterine growth retardation, Short stature OMIM:609053
Primary Myelofibrosis
Pallor, Purpura, Ecchymosis, Petechiae ORPHA:824
Myopathic Ehlers-Danlos Syndrome
Pallor ORPHA:536516
Autoimmune Hemolytic Anemia
Pallor ORPHA:98375
Mixed-Type Autoimmune Hemolytic Anemia
Pallor ORPHA:90036
Spondyloepiphyseal Dysplasia, Sensorineural Hearing Loss, Impaired Intellectual Development, And Leber Congenital Amaurosis
Sensorineural hearing impairment, Optic disc pallor, Abnormal auditory evoked potentials OMIM:619260
Congenital Dyserythropoietic Anemia Type Iii
Pallor, Short stature ORPHA:98870
Cone-Rod Dystrophy 8
Pallor OMIM:605549
Arthrogryposis, Distal, Type 2A
Failure to thrive, Hearing impairment, Abnormal auditory evoked potentials, Small for gestational... OMIM:193700
Dravet Syndrome
Pallor ORPHA:33069
Non-Functioning Paraganglioma
Pallor ORPHA:94080
Infantile Krabbe Disease
Failure to thrive, Decreased nerve conduction velocity, Cachexia, Optic atrophy, Hearing impairme... ORPHA:206436
Tay-Sachs Disease
Pallor OMIM:272800
Chronic Bilirubin Encephalopathy
Sensorineural hearing impairment, Abnormal auditory evoked potentials ORPHA:529808
Acute Bilirubin Encephalopathy
Sensorineural hearing impairment, Abnormal auditory evoked potentials ORPHA:529799
Deafness-Lymphedema-Leukemia Syndrome
Pallor ORPHA:3226
Acquired Idiopathic Sideroblastic Anemia
Pallor ORPHA:75564
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency
Pallor ORPHA:13
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency
Pallor OMIM:246450
Autoimmune Hemolytic Anemia, Warm Type
Pallor ORPHA:90033
Late-Infantile/Juvenile Krabbe Disease
EEG with persistent abnormal rhythmic activity, Decreased nerve conduction velocity, Prolonged br... ORPHA:206443
Rheumatic Fever
Pallor, Erythema ORPHA:3099
Hereditary Spherocytosis
Skin ulcer, Growth delay, Pallor ORPHA:822
Myopathy, Mitochondrial, And Ataxia
Pallor, Growth delay, Short stature OMIM:617675
American Trypanosomiasis
Pallor ORPHA:3386
Generalized Juvenile Polyposis/Juvenile Polyposis Coli
Growth delay, Anemic pallor ORPHA:329971
Idiopathic Pulmonary Hemosiderosis
Pallor ORPHA:99931
Senior-Loken Syndrome 8
Pallor OMIM:616307
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts
Pallor, Growth delay ORPHA:300298
Hyperinsulinism Due To Hnf4A Deficiency
Pallor ORPHA:263455
Letterer-Siwe Disease
Pallor OMIM:246400
Plummer-Vinson Syndrome
Pallor ORPHA:54028
Central Nervous System Calcification-Deafness-Tubular Acidosis-Anemia Syndrome
Absent brainstem auditory responses, Vestibular areflexia ORPHA:3240
Adult Krabbe Disease
EEG abnormality, Prolonged brainstem auditory evoked potentials ORPHA:206448
Childhood Absence Epilepsy
Pallor ORPHA:64280
Charcot-Marie-Tooth Disease Type 1F
Sensorineural hearing impairment, Absent brainstem auditory responses, Optic nerve hypoplasia, De... ORPHA:101085
Cockayne Syndrome Type 1
Absent brainstem auditory responses, Failure to thrive, Optic atrophy, Macrotia, Abnormality of p... ORPHA:90321
Adult-Onset Autosomal Dominant Leukodystrophy
Sensorineural hearing impairment, Abnormal autonomic nervous system physiology, Orthostatic hypot... ORPHA:99027
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema
Pallor OMIM:194380
Hereditary Folate Malabsorption
Pallor ORPHA:90045
Dominant Beta-Thalassemia
Skin ulcer, Growth delay, Pallor, Delayed puberty ORPHA:231226
Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, And Hirschsprung Disease
Sensorineural hearing impairment, Absent brainstem auditory responses, Hypoplasia of the semicirc... OMIM:609136
Trisomy 10P
EEG with focal spikes, Abnormality of the ear, Small for gestational age, EEG with burst suppress... ORPHA:171929
Fumarase Deficiency
Pallor OMIM:606812
Cockayne Syndrome B
Sensorineural hearing impairment, Failure to thrive, Abnormal pinna morphology, Decreased nerve c... OMIM:133540
Fructose-1,6-Bisphosphatase Deficiency
Pallor ORPHA:348
Retinitis Pigmentosa And Erythrocytic Microcytosis
Pallor OMIM:616959
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency
Pallor OMIM:300908
Rare Circulatory System Disease
Pallor ORPHA:98028
Beta-Thalassemia Intermedia
Skin ulcer, Pallor ORPHA:231222
Sepsis In Premature Infants
Pallor, Purpura, Petechiae ORPHA:90051
Beta-Thalassemia Major
Skin ulcer, Growth delay, Pallor, Delayed puberty ORPHA:231214
Sporadic Pheochromocytoma/Secreting Paraganglioma
Pallor ORPHA:276621
Aregenerative Anemia
Pallor ORPHA:101096
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency
Pallor ORPHA:331206
Imerslund-Gräsbeck Syndrome
Pallor ORPHA:35858
Waldenström Macroglobulinemia
Pallor, Purpura ORPHA:33226
Beta-Ketothiolase Deficiency
Pallor ORPHA:134
Prolactinoma
Pallor, Delayed puberty ORPHA:2965
Non-Functioning Pituitary Adenoma
Pallor ORPHA:91349
Mogs-Cdg
Sensorineural hearing impairment, Absent brainstem auditory responses, Optic atrophy ORPHA:79330
Adenohypophysitis
Pallor ORPHA:95512
Refractory Anemia With Excess Blasts
Anemic pallor ORPHA:86839
Incontinentia Pigmenti
Pallor, Erythema, Short stature OMIM:308300
Sheehan Syndrome
Pallor, Dry skin ORPHA:91355
Pituitary Apoplexy
Pallor ORPHA:95613
Systemic Mastocytosis With Associated Hematologic Neoplasm
Pallor ORPHA:98849
Panhypophysitis
Pallor ORPHA:95513
Cockayne Syndrome A
Sensorineural hearing impairment, Failure to thrive, Abnormal pinna morphology, Decreased nerve c... OMIM:216400
3-Hydroxy-3-Methylglutaric Aciduria
Pallor ORPHA:20
Hereditary Pheochromocytoma-Paraganglioma
Pallor ORPHA:29072
Fanconi Anemia, Complementation Group C
Anemic pallor, Intrauterine growth retardation, Short stature OMIM:227645
Mend Syndrome
Failure to thrive, Low-set ears, Abnormal auditory evoked potentials ORPHA:401973
Fanconi Anemia, Complementation Group E
Anemic pallor, Short stature OMIM:600901
Cerebrotendinous Xanthomatosis
Optic neuropathy, Abnormal motor evoked potentials, Decreased nerve conduction velocity, Optic at... ORPHA:909
Diamond-Blackfan Anemia 1
Pallor, Intrauterine growth retardation, Short stature OMIM:105650
Alternating Hemiplegia Of Childhood
Pallor ORPHA:2131
Pearson Marrow-Pancreas Syndrome
Pallor, Erythema OMIM:557000
Fanconi Anemia, Complementation Group A
Anemic pallor, Short stature OMIM:227650
Esophageal Atresia
Pallor, Growth delay ORPHA:1199
Tsh-Secreting Pituitary Adenoma
Pallor, Delayed puberty ORPHA:91347
Histiocytoid Cardiomyopathy
Pallor ORPHA:137675
Degcags Syndrome
Pallor, Intrauterine growth retardation OMIM:619488
Idiopathic Hypereosinophilic Syndrome
Pallor ORPHA:3260
Autosomal Recessive Malignant Osteopetrosis
Pallor, Growth delay ORPHA:667
Blackfan-Diamond Anemia
Pallor, Growth delay, Short stature ORPHA:124
Fanconi Anemia, Complementation Group D2
Anemic pallor, Short stature OMIM:227646
Multiple Endocrine Neoplasia Type 2
Pallor ORPHA:653
Baraitser-Winter Syndrome 2
Hearing impairment, Abnormal pinna morphology OMIM:614583
Infection-Related Hemolytic Uremic Syndrome
Pallor ORPHA:544482
Von Hippel-Lindau Disease
Pallor ORPHA:892
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3
Pallor OMIM:253280
Goodpasture Syndrome
Pallor OMIM:233450
Congenital Total Pulmonary Venous Return Anomaly
Pallor ORPHA:99125
Baraitser-Winter Cerebrofrontofacial Syndrome
Failure to thrive, Optic disc coloboma ORPHA:2995

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Actg1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Actg1.

No publications found that use IMPC mice or data for Actg1.

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MGI Allele Allele Type Produced
Actg1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Actg1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, ES Cells
Actg1tm213677(L1L2_Bact_P) Reporter-tagged deletion allele (with selection cassette) Targeting vectors

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