Genes Phenotypes

Gene: Actc1

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Name
actin, alpha, cardiac muscle 1
MGI ID
MGI:87905
Synonyms
Actc-1 alphac-actin
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (148) All data table (292)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal visceral yolk sac morphology Actc1em1(IMPC)Mbp HET E9.5 0.00
abnormal prepulse inhibition Actc1em1(IMPC)Mbp HET Early adult 8.21×10-06
increased prepulse inhibition Actc1em1(IMPC)Mbp HET Early adult 2.03×10-06
abnormal heart weight Actc1em1(IMPC)Mbp HET Early adult 2.68×10-05
abnormal neural tube closure Actc1em1(IMPC)Mbp HET E9.5 0.00
abnormal midbrain development Actc1em1(IMPC)Mbp HET E9.5 0.00
abnormal craniofacial morphology Actc1em1(IMPC)Mbp HOM E15.5 0.00
abnormal hindbrain development Actc1em1(IMPC)Mbp HET E9.5 0.00
abnormal erythrocyte cell number Actc1em1(IMPC)Mbp HET Early adult 3.66×10-05
abnormal neural tube morphology Actc1em1(IMPC)Mbp HET E9.5 0.00
preweaning lethality, complete penetrance Actc1em1(IMPC)Mbp HOM Early adult 0.00

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 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Actc1em1(IMPC)Mbp Exon Deletion Mice, Tissue
Actc1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Actc1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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