Gene: Chrnb2

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Name
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
MGI ID
MGI:87891
Synonyms
[b]2-nAchR Acrb-2 Acrb2 C030030P04Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount Chrnb2tm1b(EUCOMM)Hmgu HOM   Early adult 1.01×10-05
increased circulating aspartate transaminase level Chrnb2tm1b(EUCOMM)Hmgu HET Early adult 7.78×10-05
abnormal epididymis morphology Chrnb2tm1b(EUCOMM)Hmgu HOM Early adult 0.00
enlarged heart Chrnb2tm1b(EUCOMM)Hmgu HOM Early adult 0.00
preweaning lethality, incomplete penetrance Chrnb2tm1b(EUCOMM)Hmgu HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2)  Wholemount images
2 No  (1/584) N/A
2 No N/A
2 No  (4/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (7/408) N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (21/584)  (2/2)  Wholemount images
2 No  (10/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584) N/A
2 No N/A
2 No  (5/584) N/A
2 No  (1/562) N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (12/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (9/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (3/584) N/A
2 No  (12/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (6/584)  (1/2)  Wholemount images
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (3/584) N/A
2 No N/A
2 No N/A
2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
Echo: M-Mode Images
19 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
Immunophenotyping: Panel B FCS file(s)
8 Images
Immunophenotyping: Panel A FCS file(s)
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Chrnb2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Chrnb2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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