Genes Phenotypes

Gene: Ace

Name
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
MGI ID
MGI:87874
Synonyms
CD143
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (158) All data table (577)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal seminal vesicle morphology Acetm1.1(KOMP)Vlcg HET postnatal 0.00
embryonic growth retardation Acetm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
abnormal embryo size Acetm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Acetm1.1(KOMP)Vlcg HOM n/a 0.00
embryonic lethality prior to tooth bud stage Acetm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
embryonic growth retardation Acetm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal embryo size Acetm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (1/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127)  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No  (2/2) N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No  (1/2) N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (1/2) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (2/2) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No  (1/2) N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Acetm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acetm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acetm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells