Genes Phenotypes

Gene: Ace

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Name
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
MGI ID
MGI:87874
Synonyms
CD143
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (160) All data table (426)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Acetm1.1(KOMP)Vlcg HET E9.5 0.00
embryonic growth retardation Acetm1.1(KOMP)Vlcg HET E9.5 0.00
embryonic growth retardation Acetm1.1(KOMP)Vlcg HOM E9.5 0.00
preweaning lethality, complete penetrance Acetm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal seminal vesicle morphology Acetm1.1(KOMP)Vlcg HET Early adult 0.00
embryonic lethality prior to tooth bud stage Acetm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal embryo size Acetm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Section images
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (2/2)  Section images
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (1/2)  Section images
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127)  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No  (2/2)  Section images
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2)  Section images
Parathyroid gland 2 No N/A
Parotid gland 2 No  (1/2)  Section images
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (2/2)  Section images
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (5)
adipose tissue (5)
Brown adipose tissue expression
MA:0000057
digestive system (31)
Cecum expression
MA:0000334
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (7)
Parotid gland expression
MA:0001585
immune system (7)
Mesenteric Lymph Node expression
MA:0002829
integumental system (4)
Skin expression
MA:0000151
musculoskeletal system (1)
Quadriceps expression
MA:0002363
postnatal mouse (72)
Adrenal gland expression
MA:0000116
reproductive system (9)
Epididymis expression
MA:0000397
respiratory system (16)
Lung no expression
MA:0000415
sensory organ (6)
Harderian Gland expression
MA:0001247
set of connective tissues (5)
Brown adipose tissue expression
MA:0000057
trunk (47)
Adrenal gland expression
MA:0000116
urinary system (4)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
77 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acetm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acetm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acetm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells