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Genes Phenotypes

Gene: Acat2

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Name
acetyl-Coenzyme A acetyltransferase 2
MGI ID
MGI:87871
Synonyms
Tcp-1x Tcp1-rs1
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (222) All data table (595)
Expression & images (111) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal body wall morphology Acat2tm1b(KOMP)Wtsi HOM E18.5 0.00
preweaning lethality, complete penetrance Acat2tm1b(KOMP)Wtsi HOM   Early adult 0.00
abnormal embryo size Acat2tm1b(KOMP)Wtsi HOM E18.5 0.00
increased circulating chloride level Acat2tm1b(KOMP)Wtsi HET Early adult 7.65×10-07
increased body length Acat2tm1b(KOMP)Wtsi HET   Early adult 7.68×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Wholemount images
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/377) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2)  Wholemount images
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (2/2)  Wholemount images
Trachea 2 No  (2/590)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No  (2/2)  Wholemount images
LacZ Wholemount Images
adipose tissue (3)
Adrenal gland expression
White Adipose Tissue expression
MA:0000058
MA:0000116
digestive system (1)
Trachea expression
Esophagus expression
Thyroid gland expression
Parathyroid gland expression
MA:0000128
MA:0000441
MA:0000129
MA:0000352
endocrine system (2)
Adrenal gland expression
White Adipose Tissue expression
MA:0000058
MA:0000116
integumental system (1)
Skin expression
MA:0000151
nervous system (3)
Brain expression
Brain expression
Brain expression
Cerebral Cortex expression
Hippocampus expression
Olfactory Lobe expression
MA:0000191
MA:0000168
MA:0002413
MA:0000185
postnatal mouse (12)
Adrenal gland expression
White Adipose Tissue expression
MA:0000058
MA:0000116
reproductive system (2)
Ovary ambiguous
Oviduct expression
MA:0000384
MA:0000385
respiratory system (1)
Trachea expression
Esophagus expression
Thyroid gland expression
Parathyroid gland expression
MA:0000128
MA:0000441
MA:0000129
MA:0000352
set of connective tissues (3)
Adrenal gland expression
White Adipose Tissue expression
MA:0000058
MA:0000116
trunk (6)
Adrenal gland expression
White Adipose Tissue expression
MA:0000058
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3  (1/61)  (3/3) N/A
Axial skeleton 3  (1/65)  (3/3) N/A
Brain 3  (6/506)  (3/3) N/A
Central nervous system ganglion 3  (1/74)  (3/3) N/A
Cranium 3  (1/65)  (3/3) N/A
Dorsal root ganglion 3  (1/61)  (3/3) N/A
Ear 3  (1/506)  (3/3) N/A
Embryo 3  (1/507)  (3/3) N/A
Outer ear 3  (1/72)  (3/3) N/A
Eye 3  (1/506)  (3/3) N/A
Femur pre-cartilage condensation 3  (1/56)  (3/3) N/A
Foot 3  (1/506)  (3/3) N/A
Forearm 3  (1/303)  (3/3) N/A
Forebrain 3  (1/506)  (3/3) N/A
Forelimb 3  (1/506)  (3/3) N/A
Fronto-nasal process 3  (1/62)  (3/3) N/A
Gut 3  (1/60)  (3/3) N/A
Hand 3  (1/506)  (3/3) N/A
Head 3  (5/506)  (3/3) N/A
Head mesenchyme 3  (1/61)  (3/3) N/A
Heart 3  (1/506)  (3/3) N/A
Heart ventricle 3  (1/61)  (3/3) N/A
Hindbrain 3  (6/506)  (3/3) N/A
Hindlimb 3  (1/506)  (3/3) N/A
Humerus pre-cartilage condensation 3  (1/65)  (3/3) N/A
Inner ear 3  (1/65)  (3/3) N/A
Intestine 3  (1/59)  (3/3) N/A
Liver 3  (1/504)  (3/3) N/A
Lower leg 3  (1/303)  (3/3) N/A
Lung 3  (1/504)  (3/3) N/A
Mandibular process 3  (1/506)  (3/3) N/A
Maxillary process 3  (1/506)  (3/3) N/A
Mesonephros of female 3  (1/56)  (2/3) N/A
Mesonephros of male 3  (1/56)  (3/3) N/A
Metanephros 3  (1/56)  (3/3) N/A
Midbrain 3  (1/506)  (3/3) N/A
Nasal septum 3  (1/61)  (3/3) N/A
Nose 3  (1/76)  (3/3) N/A
Notochord 3  (1/61)  (3/3) N/A
Oral cavity 3  (1/504)  (3/3) N/A
Outflow tract 3  (1/61)  (3/3) N/A
Pancreas 3  (1/56)  (3/3) N/A
Pericardium 3  (1/56)  (3/3) N/A
Pharynx 3  (1/57)  (3/3) N/A
Radius-ulna pre-cartilage condensation 3  (1/65)  (3/3) N/A
Rib pre-cartilage condensation 3  (1/58)  (3/3) N/A
Skeleton 3  (1/76)  (3/3) N/A
Skin 3  (1/506)  (3/3) N/A
Spinal cord 3  (1/73)  (3/3) N/A
Stomach 3  (1/56)  (3/3) N/A
Tail 3  (1/506)  (3/3) N/A
Tail somite 3  (1/506)  (3/3) N/A
Thoracic vertebral cartilage condensation 3  (1/56)  (3/3) N/A
Tongue 3  (1/56)  (3/3) N/A
Trachea 3  (1/60)  (3/3) N/A
Trunk mesenchyme 3  (1/61)  (3/3) N/A
Umbilical artery embryonic part 3  (1/61)  (3/3) N/A
Umbilical vein embryonic part 3  (1/61)  (3/3) N/A
Upper arm 3  (1/303)  (3/3) N/A
Upper leg 3  (1/303)  (3/3) N/A
Urinary system 3  (1/60)  (3/3) N/A
Vibrissa 3  (1/72)  (3/3) N/A

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
15 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
15 Images
thumbnail
X-ray: XRay Images Skull Lateral Orientation
15 Images
thumbnail
X-ray: XRay Images Forepaw
15 Images
thumbnail
Embryo LacZ: LacZ images wholemount
4 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acat2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Acat2tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acat2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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