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Genes Phenotypes

Gene: Acat2

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Name
acetyl-Coenzyme A acetyltransferase 2
MGI ID
MGI:87871
Synonyms
Tcp-1x Tcp1-rs1
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (222) All data table (595)
Expression & images (111) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating chloride level Acat2tm1b(KOMP)Wtsi HET Early adult 7.65×10-07
preweaning lethality, complete penetrance Acat2tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal embryo size Acat2tm1b(KOMP)Wtsi HOM E18.5 0.00
increased body length Acat2tm1b(KOMP)Wtsi HET Early adult 7.68×10-05
abnormal body wall morphology Acat2tm1b(KOMP)Wtsi HOM E18.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Wholemount images
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/377) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2)  Wholemount images
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (2/2)  Wholemount images
Trachea 2 No  (2/590)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No  (2/2)  Wholemount images
LacZ Wholemount Images
Unassigned Top Level MA (12)
Adrenal gland expression
White Adipose Tissue expression
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3  (1/61)  (3/3) N/A
Axial skeleton 3  (1/65)  (3/3) N/A
Brain 3  (6/506)  (3/3) N/A
Central nervous system ganglion 3  (1/74)  (3/3) N/A
Cranium 3  (1/65)  (3/3) N/A
Dorsal root ganglion 3  (1/61)  (3/3) N/A
Ear 3  (1/506)  (3/3) N/A
Embryo 3  (1/507)  (3/3) N/A
Outer ear 3  (1/72)  (3/3) N/A
Eye 3  (1/506)  (3/3) N/A
Femur pre-cartilage condensation 3  (1/56)  (3/3) N/A
Foot 3  (1/506)  (3/3) N/A
Forearm 3  (1/303)  (3/3) N/A
Forebrain 3  (1/506)  (3/3) N/A
Forelimb 3  (1/506)  (3/3) N/A
Fronto-nasal process 3  (1/62)  (3/3) N/A
Gut 3  (1/60)  (3/3) N/A
Hand 3  (1/506)  (3/3) N/A
Head 3  (5/506)  (3/3) N/A
Head mesenchyme 3  (1/61)  (3/3) N/A
Heart 3  (1/506)  (3/3) N/A
Heart ventricle 3  (1/61)  (3/3) N/A
Hindbrain 3  (6/506)  (3/3) N/A
Hindlimb 3  (1/506)  (3/3) N/A
Humerus pre-cartilage condensation 3  (1/65)  (3/3) N/A
Inner ear 3  (1/65)  (3/3) N/A
Intestine 3  (1/59)  (3/3) N/A
Liver 3  (1/504)  (3/3) N/A
Lower leg 3  (1/303)  (3/3) N/A
Lung 3  (1/504)  (3/3) N/A
Mandibular process 3  (1/506)  (3/3) N/A
Maxillary process 3  (1/506)  (3/3) N/A
Mesonephros of female 3  (1/56)  (2/3) N/A
Mesonephros of male 3  (1/56)  (3/3) N/A
Metanephros 3  (1/56)  (3/3) N/A
Midbrain 3  (1/506)  (3/3) N/A
Nasal septum 3  (1/61)  (3/3) N/A
Nose 3  (1/76)  (3/3) N/A
Notochord 3  (1/61)  (3/3) N/A
Oral cavity 3  (1/504)  (3/3) N/A
Outflow tract 3  (1/61)  (3/3) N/A
Pancreas 3  (1/56)  (3/3) N/A
Pericardium 3  (1/56)  (3/3) N/A
Pharynx 3  (1/57)  (3/3) N/A
Radius-ulna pre-cartilage condensation 3  (1/65)  (3/3) N/A
Rib pre-cartilage condensation 3  (1/58)  (3/3) N/A
Skeleton 3  (1/76)  (3/3) N/A
Skin 3  (1/506)  (3/3) N/A
Spinal cord 3  (1/73)  (3/3) N/A
Stomach 3  (1/56)  (3/3) N/A
Tail 3  (1/506)  (3/3) N/A
Tail somite 3  (1/506)  (3/3) N/A
Thoracic vertebral cartilage condensation 3  (1/56)  (3/3) N/A
Tongue 3  (1/56)  (3/3) N/A
Trachea 3  (1/60)  (3/3) N/A
Trunk mesenchyme 3  (1/61)  (3/3) N/A
Umbilical artery embryonic part 3  (1/61)  (3/3) N/A
Umbilical vein embryonic part 3  (1/61)  (3/3) N/A
Upper arm 3  (1/303)  (3/3) N/A
Upper leg 3  (1/303)  (3/3) N/A
Urinary system 3  (1/60)  (3/3) N/A
Vibrissa 3  (1/72)  (3/3) N/A

 Associated Images

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X-ray: XRay Images Forepaw
15 Images
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X-ray: XRay Images Whole Body Dorso Ventral
15 Images
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X-ray: XRay Images Whole Body Lateral Orientation
15 Images
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X-ray: XRay Images Skull Lateral Orientation
15 Images
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Adult LacZ: LacZ Images Wholemount
12 Images
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Embryo LacZ: LacZ images wholemount
4 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acat2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Acat2tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acat2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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