Gene: Sh3gl2

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Name
SH3-domain GRB2-like 2
MGI ID
MGI:700009
Synonyms
9530001L19Rik endophilin A1 Sh3d2a endophilin I EEN-B1 B930049H17Rik
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 1.21×10-09
hypoactivity Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 7.09×10-07
decreased bone mineral density Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 1.40×10-17
decreased body length Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 4.78×10-09
abnormal bone structure Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 5.53×10-08
decreased vertical activity Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 2.27×10-09
decreased bone mineral content Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 1.28×10-10
decreased grip strength Sh3gl2tm1b(EUCOMM)Wtsi HOM Early adult 3.71×10-09

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Slit Lamp
1 Images
Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sh3gl2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Sh3gl2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sh3gl2tm438(L1L2_gt0) Targeting vectors
Sh3gl2tm45700(L1L2_gt0) Targeting vectors

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