Gene: Mthfsl

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Name
5, 10-methenyltetrahydrofolate synthetase-like
MGI ID
MGI:3780550
Synonyms
Gm2382
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 4.27×10-06
cataract Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 5.15×10-06
decreased grip strength Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 1.30×10-10
increased circulating HDL cholesterol level Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 9.55×10-06
decreased vertical activity Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 4.82×10-05
increased fasting circulating glucose level Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 2.28×10-05
abnormal lens morphology Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 2.00×10-06
increased circulating cholesterol level Mthfsltm1b(EUCOMM)Hmgu HOM Early adult 3.81×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood 2 No N/A
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/377) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Chest bone 2 No  (2/2)  Wholemount images
Colon 2 No  (12/127) N/A
Cranium 2 No N/A
Diaphragm 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/590)  (1/2)  Wholemount images
Hindlimb 2 No N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590)  (1/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  Wholemount images
Lymph node 2 No N/A
Main olfactory bulb 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (1/2)  Wholemount images
Prostate gland 2 No  (12/590)  Wholemount images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/590) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  Wholemount images
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/590)  Wholemount images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  Wholemount images
Uterus 2 No  Wholemount images
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
Vesicular gland 2 No  Wholemount images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
8 Images
Adult LacZ: LacZ Images Wholemount
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
5 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mthfsltm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Mthfsltm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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