Gene Summary

Name:
potassium voltage-gated channel, subfamily G, member 2
Synonyms:
N/A

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating serum albumin level Kcng2em1(IMPC)Bay HOM Early adult 4.74×10-09
hyperactivity Kcng2em1(IMPC)Bay HOM   Early adult 6.18×10-05
decreased cardiac stroke volume Kcng2em1(IMPC)Bay HOM Early adult 4.48×10-07
increased heart weight Kcng2em1(IMPC)Bay HOM Early adult 4.06×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

Eye Morphology

VIP of right eye

14 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

Eye Morphology

VIP of left eye

14 Images

X-ray

XRay Images Forepaw

10 Images

Eye Morphology

VIP of left fundus

14 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

Eye Morphology

VIP of right fundus

14 Images

Immunophenotyping

Panel B FCS file(s)

6 Images

Immunophenotyping

Panel A FCS file(s)

6 Images

Human diseases caused by Kcng2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Kcng2 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Attention Deficit-Hyperactivity Disorder
Hyperactivity, Attention deficit hyperactivity disorder OMIM:143465
Intellectual Developmental Disorder, Autosomal Dominant 45
Hyperactivity, Attention deficit hyperactivity disorder OMIM:617600
Intellectual Developmental Disorder, Autosomal Recessive 54
Hyperactivity OMIM:617028
Schizophrenia 15
Hyperactivity OMIM:613950
Obesity-Colitis-Hypothyroidism-Cardiac Hypertrophy-Developmental Delay Syndrome
Cardiomegaly, Hypoalbuminemia ORPHA:88643
22q13 deletion syndrome (Phelan-Mcdermid syndrome)
Hyperactivity DECIPHER:20
Potocki-Lupski syndrome (17p11.2 duplication syndrome)
Hyperactivity DECIPHER:19
Intellectual Developmental Disorder, Autosomal Recessive 3
Hyperactivity OMIM:608443
Focal Segmental Glomerulosclerosis 1
Hyperlipidemia, Hypertension, Hypoalbuminemia OMIM:603278
Immunodeficiency 8
Hyperactivity OMIM:615401
Hyperlysinemia, Type I
Hyperactivity, Hyperlysinemia OMIM:238700
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia
Arrhythmia, Hyperactivity, Sick sinus syndrome, Bradycardia, Attention deficit hyperactivity diso... OMIM:617182
Analbuminemia
Elevated circulating transferrin concentration, Hypercholesterolemia, Hypotension, Hypoalbuminemi... OMIM:616000
Erythroderma, Lethal Congenital
Hypoalbuminemia OMIM:227090
Ethanolaminosis
Cardiomegaly OMIM:227150
Nephrotic Syndrome, Type 2
Hyperlipidemia, Hypoalbuminemia OMIM:600995
Diarrhea 7, Protein-Losing Enteropathy Type
Hyperlipidemia, Hypoalbuminemia, Hypercholesterolemia OMIM:615863
Nephrotic Syndrome, Type 15
Hypoalbuminemia OMIM:617609
Intellectual Developmental Disorder, X-Linked 72
Hyperactivity OMIM:300271
Fibronectin Glomerulopathy
Cerebral hemorrhage, Hypertension, Hypoalbuminemia ORPHA:84090
Primary Membranoproliferative Glomerulonephritis
Myocardial infarction, Hypertension, Hypoalbuminemia ORPHA:54370
Nephrotic Syndrome, Type 9
Hypoalbuminemia OMIM:615573
Congenital Enterocyte Heparan Sulfate Deficiency
Hematochezia, Abnormal circulating polysaccharide concentration, Abnormal circulating protein con... ORPHA:103910
Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 1
Hypoalbuminemia, Hypercholesterolemia OMIM:607250
8p23.1 deletion syndrome
Atrial septal defect, Abnormal heart morphology, Hyperactivity, Atrioventricular canal defect DECIPHER:39
Intellectual Developmental Disorder, Autosomal Dominant 52
Hyperactivity OMIM:617796
Triokinase And Fmn Cyclase Deficiency Syndrome
Dilated cardiomyopathy, Reduced systolic function, Hepatomegaly, Hypoalbuminemia OMIM:618805
Enteropathy, Familial, With Villous Edema And Immunoglobulin G2 Deficiency
Hypoproteinemia, Shock, Hypoalbuminemia OMIM:600351
Intellectual Developmental Disorder, Autosomal Dominant 33
Hyperactivity OMIM:616311
Focal Segmental Glomerulosclerosis 6
Hypoalbuminemia OMIM:614131
Chylomicron Retention Disease
Hypocholesterolemia, Hypotriglyceridemia, Hypoalbuminemia, Decreased LDL cholesterol concentration OMIM:246700
Intellectual Developmental Disorder, Autosomal Recessive 37
Hyperactivity OMIM:615493
Autoinflammation With Infantile Enterocolitis
Increased circulating ferritin concentration, Diffuse alveolar hemorrhage, Splenomegaly, Elevated... OMIM:616050
Spinocerebellar Ataxia With Axonal Neuropathy Type 1
Hypoalbuminemia, Hypercholesterolemia ORPHA:94124
Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome
Hyperactivity ORPHA:356996
Immunodeficiency 43
Hypoproteinemia, Hypoalbuminemia OMIM:241600
Developmental And Epileptic Encephalopathy 43
Hyperactivity OMIM:617113
Nephrotic Syndrome, Type 6
Hypoalbuminemia OMIM:614196
Tropical Endomyocardial Fibrosis
Coronary artery stenosis, Abnormal ST segment, Right bundle branch block, Left bundle branch bloc... ORPHA:75565
Alg1-Cdg
Abnormal heart morphology, Cardiomyopathy, Hypoalbuminemia ORPHA:79327
Galloway-Mowat Syndrome 8
Hypoalbuminemia OMIM:618349
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Hypoalbuminemia OMIM:617156
Mpi-Cdg
Gastrointestinal hemorrhage, Portal hypertension, Hepatomegaly, Hypoalbuminemia ORPHA:79319
Congenital Lethal Erythroderma
Hypoalbuminemia ORPHA:1954
Congenital Disorder Of Glycosylation, Type Ih
Abnormal heart morphology, Hepatomegaly, Hypoalbuminemia, Abnormal cardiac septum morphology OMIM:608104
Nephrotic Syndrome, Type 3
Hypoalbuminemia OMIM:610725
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Hyperactivity ORPHA:436151
Smith-Magenis syndrome
Hyperactivity DECIPHER:8
Nephrotic Syndrome, Type 11
Dilated cardiomyopathy, Ventricular septal defect, Hypoalbuminemia, Hypercholesterolemia OMIM:616730
Citrullinemia Type Ii
Hypoproteinemia, Hyperlipidemia, Hypercholesterolemia, Hyperactivity, Elevated plasma citrulline,... ORPHA:247585
Immunodeficiency 27A
Hepatosplenomegaly, Splenomegaly, Hypoalbuminemia OMIM:209950
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency
Gastrointestinal hemorrhage, Hyperbilirubinemia, Hyperammonemia, Decreased HDL cholesterol concen... ORPHA:247598
Nephrotic Syndrome, Type 8
Hypoalbuminemia OMIM:615244
Rajab Interstitial Lung Disease With Brain Calcifications 2
Hypoalbuminemia, Hepatosplenomegaly, Hypertriglyceridemia OMIM:619013
Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy
Hypoproteinemia, Pulmonary embolism, Hepatomegaly, Hypoalbuminemia, Budd-Chiari syndrome OMIM:226300
Hemophagocytic Lymphohistiocytosis, Familial, 1
Increased circulating ferritin concentration, Hypoproteinemia, Hyponatremia, Splenomegaly, Hepato... OMIM:267700
Congenital Disorder Of Glycosylation, Type Ib
Hepatomegaly, Hypoalbuminemia OMIM:602579
Attrv122I Amyloidosis
Increased circulating NT-proBNP concentration, Reduced ejection fraction, Arrhythmia, Congestive ... ORPHA:85451
Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency
Dilated cardiomyopathy, Hepatosplenomegaly, Portal hypertension, Congestive heart failure, Hepato... ORPHA:367
Al Amyloidosis
Monoclonal light chain cardiac amyloidosis, Gastrointestinal hemorrhage, Arrhythmia, Jaw claudica... ORPHA:85443
Alg6-Cdg
Hypoalbuminemia, Decreased LDL cholesterol concentration ORPHA:79320
Cardiomyopathy, Familial Hypertrophic 27
Mitral regurgitation, Cardiomegaly, Tricuspid regurgitation, Prolonged QT interval OMIM:618052
Idiopathic Steroid-Resistant Nephrotic Syndrome
Hypercholesterolemia, Abnormal circulating lipid concentration, Pulmonary embolism, Hypoalbuminem... ORPHA:567548
Congenital Analbuminemia
Hypoproteinemia, Hyperlipidemia, Hypercholesterolemia, Low pulse pressure, Hypoalbuminemia, Incre... ORPHA:86816
Galloway-Mowat Syndrome 6
Hypoalbuminemia OMIM:618347
Fixed Subaortic Stenosis
Paroxysmal atrial fibrillation, Aortic regurgitation, Systolic heart murmur, Congestive heart fai... ORPHA:3092
Coronary Arterial Fistula
Right ventricular dilatation, Continuous heart murmur, Elevated jugular venous pressure, Patent f... ORPHA:2041
Leishmaniasis
Splenomegaly, Hepatomegaly, Hypoalbuminemia ORPHA:507
Macrophage Activation Syndrome
Increased circulating ferritin concentration, Splenomegaly, Hepatomegaly, Elevated circulating C-... ORPHA:158061
Cirrhotic Cardiomyopathy
Right atrial enlargement, Increased circulating NT-proBNP concentration, Left ventricular diastol... ORPHA:57777
S-Adenosylhomocysteine Hydrolase Deficiency
Hyperhomocystinemia, Hypermethioninemia, Elevated circulating creatine kinase concentration, Abno... ORPHA:88618
Ménétrier Disease
Hypoproteinemia, Gastrointestinal hemorrhage, Hypoalbuminemia ORPHA:2494
Nephrotic Syndrome, Type 1
Hypoproteinemia, Hyperlipidemia, Hypoalbuminemia OMIM:256300
Eosinophilic Gastroenteritis
Hematochezia, Elevated circulating C-reactive protein concentration, Hypoalbuminemia ORPHA:2070
Encephalopathy, Progressive, With Or Without Lipodystrophy
Hyperactivity, Hepatomegaly, Hypertriglyceridemia OMIM:615924
Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia
Hypoalbuminemia, Hypercholesterolemia OMIM:208920
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Portal hypertension, Splenomegaly, Hepatomegaly, Hyperbilirubinemia, Hypoalbuminemia OMIM:251880
Congenital Enterovirus Infection
Myocarditis, Hypotension, Cardiomyopathy, Hypoalbuminemia, Pericardial effusion, Hyperammonemia ORPHA:292
Intellectual Developmental Disorder, X-Linked 77
Hyperactivity OMIM:300454
Hepatoportal Sclerosis
Portal hypertension, Gastrointestinal hemorrhage, Splenomegaly, Hyperbilirubinemia, Hypoalbuminemia ORPHA:64743
Hyperprolinemia, Type I
Hyperprolinemia, Hyperactivity OMIM:239500
Leigh Syndrome With Nephrotic Syndrome
Cardiomegaly, Hypoalbuminemia ORPHA:255249
Cardiomyopathy, Familial Hypertrophic, 4
Ventricular fibrillation, Cardiac arrest, Hypertrophic cardiomyopathy, Hepatomegaly, Right bundle... OMIM:115197
Diarrhea 10, Protein-Losing Enteropathy Type
Hematochezia, Hyponatremia, Hypocalcemia, Hypertriglyceridemia, Hypoalbuminemia, Hypomagnesemia, ... OMIM:618183
Spinocerebellar Ataxia With Axonal Neuropathy Type 2
Elevated circulating creatine kinase concentration, Elevated alpha-fetoprotein, Hypoalbuminemia, ... ORPHA:64753
Hemophagocytic Lymphohistiocytosis, Familial, 2
Increased circulating ferritin concentration, Hypoproteinemia, Hepatosplenomegaly, Hyponatremia, ... OMIM:603553
Isolated Right Ventricular Hypoplasia
Right atrial enlargement, Patent foramen ovale, Systolic heart murmur, Congestive heart failure, ... ORPHA:439
Aicardi-Goutieres Syndrome 9
Hepatosplenomegaly, Portal hypertension, Hepatomegaly, Hypertension, Increased blood pressure, Hy... OMIM:619487
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type
Hyperactivity, Attention deficit hyperactivity disorder OMIM:301008
Mucopolysaccharidosis-Plus Syndrome
Enlarged kidney, Congestive heart failure, Atrial septal defect, Hypertrophic cardiomyopathy, Spl... OMIM:617303
Amoebiasis Due To Entamoeba Histolytica
Constrictive pericarditis, Abnormal pericardium morphology, Hypoalbuminemia, Congestive heart fai... ORPHA:67
Congenitally Uncorrected Transposition Of The Great Arteries
Abnormal pulmonary valve morphology, Congestive heart failure, Atrial septal defect, Biventricula... ORPHA:860
Wolcott-Rallison Syndrome
Hyponatremia, Atrial septal defect, Hepatomegaly, Double outlet right ventricle, Hyperbilirubinem... ORPHA:1667
Refractory Celiac Disease
Hypoproteinemia, Hypocalcemia, Hypophosphatemia, Hypoalbuminemia, Hypomagnesemia ORPHA:398063
Danon Disease
Dilated cardiomyopathy, Arrhythmia, Wolff-Parkinson-White syndrome, Hypertrophic cardiomyopathy, ... OMIM:300257
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Dilated cardiomyopathy, Ventricular tachycardia, Hepatomegaly, Elevated circulating creatine kina... OMIM:600649
Nephrotic Syndrome, Type 14
Hypoalbuminemia, Hypertriglyceridemia OMIM:617575
Intellectual Developmental Disorder, X-Linked 101
Hyperactivity OMIM:300928
Familial Hemophagocytic Lymphohistiocytosis
Increased circulating ferritin concentration, Splenomegaly, Hepatomegaly, Hypoalbuminemia, Hypert... ORPHA:540
Bacterial Toxic-Shock Syndrome
Elevated circulating creatinine concentration, Hypocalcemia, Myocarditis, Hypotension, Capillary ... ORPHA:36234
Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 2
Hypoalbuminemia OMIM:614441
Familial Atrial Myxoma
Cardiac myxoma, Congestive heart failure, Bacterial endocarditis, Heart murmur, Pulmonic valve my... ORPHA:615
Glycine Encephalopathy
Hyperglycinemia, Hyperactivity OMIM:605899
Refractory Anemia With Excess Blasts
Palpitations, Abnormal circulating albumin concentration, Abnormal circulating protein concentrat... ORPHA:86839
Primary Intestinal Lymphangiectasia
Hypoproteinemia, Hypocalcemia, Hypoalbuminemia, Hypomagnesemia, Pericardial effusion ORPHA:90362
Mucopolysaccharidosis-Like Syndrome With Congenital Heart Defects And Hematopoietic Disorders
Enlarged kidney, Hepatosplenomegaly, Patent foramen ovale, Congestive heart failure, Atrial septa... ORPHA:505248
Combined Oxidative Phosphorylation Deficiency 33
Hepatomegaly, Elevated circulating creatine kinase concentration, Cardiomyopathy, Cardiomegaly, L... OMIM:617713
Genetic Steroid-Resistant Nephrotic Syndrome
Hypoalbuminemia ORPHA:656
Intellectual Developmental Disorder With Epilepsy, Behavioral Abnormalities, And Coarse Facies
Hyperactivity OMIM:619031
Hennekam Lymphangiectasia-Lymphedema Syndrome 1
Atrial septal defect, Hyperactivity, Ventricular septal defect, Hypoalbuminemia, Pericardial lymp... OMIM:235510
Complete Atrioventricular Septal Defect
Left-to-right shunt, Right bundle branch block, Pulmonary venous hypertension, Third heart sound,... ORPHA:1329
Congenital Disorder Of Glycosylation, Type Ia
Hepatomegaly, Cardiomyopathy, Hypoalbuminemia, Hypocholesterolemia, Pericardial effusion OMIM:212065
Abetalipoproteinemia
Congestive heart failure, Hypotriglyceridemia, Hepatomegaly, Decreased HDL cholesterol concentrat... ORPHA:14
Chronic Bilirubin Encephalopathy
Neonatal hyperbilirubinemia, Hypernatremia, Hypoalbuminemia ORPHA:529808
Acute Bilirubin Encephalopathy
Hypernatremia, Neonatal hyperbilirubinemia, Hypoalbuminemia ORPHA:529799
Morm Syndrome
Hyperactivity ORPHA:75858
Combined Oxidative Phosphorylation Deficiency 37
Hypertrophic cardiomyopathy, Hyperalaninemia, Hypoalbuminemia OMIM:618329
Intellectual Developmental Disorder, X-Linked, Syndromic 32
Cardiomegaly, Congestive heart failure OMIM:300886
Trichohepatoenteric Syndrome 1
Tetralogy of Fallot, Aortic regurgitation, Hypermethioninemia, Hepatomegaly, Pulmonic stenosis, A... OMIM:222470
Avian Influenza
Elevated circulating creatine kinase concentration, Elevated circulating C-reactive protein conce... ORPHA:454836
Attrv30M Amyloidosis
Cardiomegaly, Cardiomyopathy, Arrhythmia, Atrioventricular block ORPHA:85447
Carnitine Palmitoyltransferase I Deficiency
Transient hyperlipidemia, Arrhythmia, Hepatomegaly, Elevated circulating creatine kinase concentr... OMIM:255120
Juvenile Polyposis Syndrome
Hematochezia, Hypokalemia, Hypoalbuminemia OMIM:174900
Phenylketonuria
Hyperactivity, Maternal hyperphenylalaninemia, Hyperphenylalaninemia, Attention deficit hyperacti... OMIM:261600
Juvenile Polyposis Of Infancy
Hematochezia, Gastrointestinal hemorrhage, Atrial septal defect, Abnormal heart morphology, Intes... ORPHA:79076
Intellectual Developmental Disorder, Autosomal Recessive 71
Hyperactivity, Ventricular septal defect, Attention deficit hyperactivity disorder OMIM:618504
Mitochondrial Complex Iv Deficiency, Nuclear Type 12
Elevated circulating creatine kinase concentration, Intraventricular hemorrhage, Hypoalbuminemia OMIM:619055
Secondary Intestinal Lymphangiectasia
Constrictive pericarditis, Intestinal bleeding, Hypoalbuminemia, Reduced circulating transferrin ... ORPHA:90363
Autosomal Recessive Generalized Dystrophic Epidermolysis Bullosa, Intermediate Form
Dilated cardiomyopathy, Decreased serum zinc, Decreased serum iron, Decreased plasma carnitine, H... ORPHA:89842
Marburg Hemorrhagic Fever
Subconjunctival hemorrhage, Hypokalemia, Hypovolemia, Elevated circulating creatinine concentrati... ORPHA:99826
Primary Biliary Cholangitis
Orthostatic hypotension, Portal hypertension, Abnormal circulating lipid concentration, Conjugate... ORPHA:186
Hepatocellular Carcinoma
Hypokalemia, Hyponatremia, Portal hypertension, Hypercalcemia, Hypotension, Hepatomegaly, Hyperbi... ORPHA:88673
Hemochromatosis, Type 1
Increased circulating ferritin concentration, Arrhythmia, Congestive heart failure, Telangiectasi... OMIM:235200
Idiopathic Steroid-Sensitive Nephrotic Syndrome With Secondary Steroid Resistance
Pulmonary embolism, Hyperlipidemia, Hypertension, Hypoalbuminemia ORPHA:567546
Familial Idiopathic Dilatation Of The Right Atrium
Right atrial enlargement, Midsystolic murmur, Paroxysmal atrial fibrillation, Holosystolic murmur... ORPHA:1677
Mucopolysaccharidosis, Type Iiib
Hyperactivity, Splenomegaly, Hepatomegaly, Asymmetric septal hypertrophy, Cardiomegaly OMIM:252920
Alg12-Cdg
Hyponatremia, Patent foramen ovale, Biventricular hypertrophy, Muscular ventricular septal defect... ORPHA:79324
Galloway-Mowat Syndrome 3
Hypertension, Hypoalbuminemia OMIM:617729
Chromosome 15Q25 Deletion Syndrome
Attention deficit hyperactivity disorder, Hyperactivity, Dextrocardia, Abnormal cardiac septum mo... OMIM:614294
Xfe Progeroid Syndrome
Hypertension, Hypoalbuminemia OMIM:610965
Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome
Abnormal blood ion concentration, Hypocalcemia, Splenomegaly, Hypoalbuminemia, Hypomagnesemia, De... ORPHA:37042
Naxos Disease
Dilated cardiomyopathy, Paroxysmal ventricular tachycardia, Premature ventricular contraction, Ab... OMIM:601214
Congenital Tricuspid Valve Dysplasia
Right atrial enlargement, Abnormal tricuspid valve leaflet morphology, Patent foramen ovale, Syst... ORPHA:555874
Histidinemia
Hyperactivity, Hyperhistidinemia ORPHA:2157
Insulin-Resistance Syndrome Type B
Abnormal circulating lipid concentration, Hypotriglyceridemia, Enlarged ovaries, Enlarged polycys... ORPHA:2298
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency
Hyperactivity, Transient hyperphenylalaninemia OMIM:612716
Biliary, Renal, Neurologic, And Skeletal Syndrome
Cardiac arrest, Elevated circulating creatinine concentration, Left-to-right shunt, Dextrocardia,... OMIM:619534
Neurodevelopmental Disorder With Or Without Autism Or Seizures
Atrial septal defect, Hyperactivity, Pulmonic stenosis OMIM:619239
Primary Sclerosing Cholangitis
Spider hemangioma, Hepatosplenomegaly, Portal hypertension, Congestive heart failure, Splenomegal... ORPHA:171
Aorta Coarctation
Tetralogy of Fallot, Cardiomegaly, Congestive heart failure, Pulmonary arterial hypertension, Hyp... ORPHA:1457
Graves Disease, Susceptibility To, 1
Hyperactivity, Congestive heart failure OMIM:275000
Hypomagnesemia, Seizures, And Mental Retardation 2
Hypomagnesemia, Hyperactivity, Hypokalemia OMIM:618314
Galloway-Mowat Syndrome 1
Hypoalbuminemia OMIM:251300
Myopathy With Extrapyramidal Signs
Hyperlysinemia, Hyperactivity, Splenomegaly, Hepatomegaly, Hypervalinemia, Elevated circulating c... OMIM:615673
Glycogen Storage Disease Of Heart, Lethal Congenital
Shortened PR interval, Congestive heart failure, Biventricular hypertrophy, Hypotension, Cardiomy... OMIM:261740
Combined Oxidative Phosphorylation Deficiency 41
Elevated circulating creatine kinase concentration, Cardiomegaly OMIM:618838
Autosomal Dominant Generalized Epidermolysis Bullosa Simplex, Severe Form
Hypoalbuminemia ORPHA:79396
Mucopolysaccharidosis, Type Iiia
Asymmetric septal hypertrophy, Hyperactivity, Splenomegaly, Hepatomegaly OMIM:252900
Glycogen Storage Disease Due To Acid Maltase Deficiency, Infantile Onset
Shortened PR interval, Hypertrophic cardiomyopathy, Hepatomegaly, Elevated circulating creatine k... ORPHA:308552
Intellectual Developmental Disorder, X-Linked 107
Hyperactivity, Attention deficit hyperactivity disorder OMIM:301013
Rajab Interstitial Lung Disease With Brain Calcifications 1
Hypocalcemia, Unconjugated hyperbilirubinemia, Portal hypertension, Hypoalbuminemia OMIM:613658
Hyperthyroidism, Nonautoimmune
Tachycardia, Hyperactivity OMIM:609152
Mucopolysaccharidosis, Type Iiic
Asymmetric septal hypertrophy, Hyperactivity, Splenomegaly, Hepatomegaly OMIM:252930
Absence Of The Pulmonary Artery
Tetralogy of Fallot, Atrial flutter, Patent foramen ovale, Reduced ejection fraction, Congestive ... ORPHA:980
Spastic Paraplegia 29, Autosomal Dominant
Neonatal hyperbilirubinemia, Hyperactivity OMIM:609727
Immunodeficiency 82 With Systemic Inflammation
Vasculitis in the skin, Splenomegaly, Elevated circulating C-reactive protein concentration, Hypo... OMIM:619381
Symptomatic Form Of Fragile X Syndrome In Female Carriers
Hyperactivity, Mitral valve prolapse, Hypertension, Attention deficit hyperactivity disorder ORPHA:449291
X-Linked Intellectual Disability-Acromegaly-Hyperactivity Syndrome
Hyperactivity ORPHA:85327
Argininemia
Hyperactivity, Hyperargininemia, Hepatomegaly, Hyperammonemia OMIM:207800
Epidermolysis Bullosa, Junctional 7, With Interstitial Lung Disease And Nephrotic Syndrome
Hypoalbuminemia OMIM:614748
Maternal Phenylketonuria
Tetralogy of Fallot, Hyperactivity, Double outlet right ventricle, Hypoplastic left heart, Abnorm... ORPHA:2209
Legius Syndrome
Hyperactivity, Pulmonic stenosis, Mitral valve prolapse, Paroxysmal atrial tachycardia, Attention... ORPHA:137605
Pmm2-Cdg
Hypertrophic cardiomyopathy, Hypoalbuminemia, Pericarditis, Reduced thyroxin-binding globulin, An... ORPHA:79318
Congenital Total Pulmonary Venous Return Anomaly
Mixed total anomalous pulmonary venous connection, Dextrocardia, Double outlet right ventricle, H... ORPHA:99125

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Kcng2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Kcng2.

No publications found that use IMPC mice or data for Kcng2.

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MGI Allele Allele Type Produced
Kcng2em1(IMPC)Bay Exon Deletion Mice, Tissue
Kcng2tm466063(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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