Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
vomeronasal 2, receptor 65
Synonyms:
N/A

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Vmn2r65 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Vmn2r65 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Autism, Susceptibility To, 20
Impaired social interactions OMIM:618830
Asperger Syndrome, Susceptibility To, 1
Impaired ability to form peer relationships, Impaired use of nonverbal behaviors OMIM:608638
Asperger Syndrome, X-Linked, Susceptibility To, 2
Impaired ability to form peer relationships, Impaired use of nonverbal behaviors OMIM:300497
Asperger Syndrome, X-Linked, Susceptibility To, 1
Impaired ability to form peer relationships, Impaired use of nonverbal behaviors OMIM:300494
Asperger Syndrome, Susceptibility To, 2
Impaired ability to form peer relationships, Impaired use of nonverbal behaviors OMIM:608631
Mental Retardation, Autosomal Recessive 66
Shyness, Aggressive behavior OMIM:618221
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Abnormal social behavior ORPHA:436151
Severe Early-Onset Obesity-Insulin Resistance Syndrome Due To Sh2B1 Deficiency
Impaired social interactions, No social interaction, Aggressive behavior ORPHA:329249
Chromosome Xp11.23-P11.22 Duplication Syndrome
Shyness OMIM:300801
Early-Onset Schizophrenia
Shyness, Abnormal emotion/affect behavior, Diminished motivation, Anhedonia, Emotional lability, ... ORPHA:96369
Female Restricted Epilepsy With Intellectual Disability
Anxiety, Abnormal social behavior, Aggressive behavior ORPHA:101039
Dopa-Responsive Dystonia
Abnormal social behavior, Agoraphobia, Emotional lability, Panic attack, Irritability, Anxiety ORPHA:255
Hsd10 Disease
Abnormal social behavior ORPHA:391417
11Q22.2Q22.3 Microdeletion Syndrome
Poor eye contact, Anxiety, Abnormal social behavior ORPHA:444002
Lamb-Shaffer Syndrome
Abnormal social behavior ORPHA:530983
Childhood Absence Epilepsy
Abnormal social behavior, Anxiety ORPHA:64280
48,Xxxy Syndrome
Abnormal social behavior, Irritability, Anxiety, Abnormal aggressive, impulsive or violent behavior ORPHA:96263
Early-Onset Autosomal Dominant Alzheimer Disease
Abnormal social behavior ORPHA:1020
Metachromatic Leukodystrophy, Late Infantile Form
Abnormal social behavior, Emotional lability ORPHA:309256
Metachromatic Leukodystrophy, Juvenile Form
Abnormal social behavior, Emotional lability ORPHA:309263
Prader-Willi Syndrome Due To Translocation
Impaired social interactions, Skin-picking, Abnormal social behavior, Head-banging, Anxiety, Happ... ORPHA:177907
Fg Syndrome Type 1
Abnormal social behavior ORPHA:93932
Metachromatic Leukodystrophy, Adult Form
Abnormal social behavior, Emotional lability ORPHA:309271
Dihydropyrimidine Dehydrogenase Deficiency
Abnormal social behavior, Irritability, Abnormal aggressive, impulsive or violent behavior ORPHA:1675
Non-Progressive Cerebellar Ataxia With Intellectual Disability
Abnormal social behavior, Aggressive behavior ORPHA:314647
Mend Syndrome
Abnormal social behavior, Aggressive behavior ORPHA:401973
Tuberous Sclerosis Complex
Anxiety, Abnormal social behavior, Self-injurious behavior, Aggressive behavior ORPHA:805
Niemann-Pick Disease Type C
Abnormal social behavior, Low frustration tolerance, Aggressive behavior, Apathy ORPHA:646
Koolen-De Vries Syndrome Due To A Point Mutation
Anxiety, Abnormal social behavior, Overfriendliness ORPHA:363965
17Q21.31 Microdeletion Syndrome
Anxiety, Abnormal social behavior, Overfriendliness ORPHA:363958
Williams Syndrome
Anxiety, Abnormal social behavior, Overfriendliness ORPHA:904

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Vmn2r65

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Vmn2r65.

No publications found that use IMPC mice or data for Vmn2r65.

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