Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
microRNA 455
Synonyms:
Mirn455,  mir 455,  mmu-mir-455

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Mir455 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Mir455 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Genochondromatosis Type 1
Multiple enchondromatosis ORPHA:85197
Legg-Calvé-Perthes Disease
Cartilage destruction ORPHA:2380
Enchondromatosis, Multiple, Ollier Type
Multiple enchondromatosis OMIM:166000
Multiple Enchondromatosis, Maffucci Type
Multiple enchondromatosis OMIM:614569
Ollier Disease
Multiple enchondromatosis, Abnormal cartilage morphology ORPHA:296
Larsen-Like Syndrome, Lethal Type
Abnormal cartilage matrix OMIM:245650
Short Stature, Brussels Type
Calcification of cartilage ORPHA:2867
Familial Calcium Pyrophosphate Deposition
Calcification of cartilage ORPHA:1416
Lethal Kniest-Like Dysplasia
Abnormal cartilage morphology, Abnormal cartilage matrix ORPHA:2347
Atelosteogenesis, Type Ii
Lacunar halos around chondrocytes OMIM:256050
Keutel Syndrome
Calcification of cartilage ORPHA:85202
Tracheobronchopathia Osteochondroplastica
Calcification of cartilage ORPHA:3348
Kniest Dysplasia
Abnormal cartilage collagen OMIM:156550
Lissencephaly Type 3-Metacarpal Bone Dysplasia Syndrome
Abnormal cartilage matrix ORPHA:86822
Spondyloepiphyseal Dysplasia Tarda
Abnormal cartilage morphology ORPHA:93284
Moderate Hemophilia A
Cartilage destruction ORPHA:169805
Kniest Dysplasia
Abnormal cartilage collagen ORPHA:485
Adult-Onset Still Disease
Cartilage destruction ORPHA:829
Encephalocraniocutaneous Lipomatosis
Abnormal cartilage morphology ORPHA:2396
Reactive Arthritis
Cartilage destruction ORPHA:29207
Alkaptonuria
Cartilage destruction, Calcification of cartilage ORPHA:56
Multiple Osteochondromas
Abnormal cartilage morphology ORPHA:321
Spondylometaepiphyseal Dysplasia, Short Limb-Hand Type
Progressive calcification of costochondral cartilage, Calcification of cartilage OMIM:271665

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Mir455

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mir455.

No publications found that use IMPC mice or data for Mir455.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Mir455tm1(mirKO)Wtsi Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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