banner
Genes Phenotypes Help, News, Blog

Gene: Tmprss9 MGI:3612246

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
transmembrane protease, serine 9
Synonyms:
Serase-1B

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Tmprss9 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Tmprss9 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Autism, Susceptibility To, 20
Attention deficit hyperactivity disorder, Impaired social interactions OMIM:618830
Maturity-Onset Diabetes Of The Young, Type 11
Overweight, Obesity OMIM:613375
Hereditary Geniospasm
Abnormal social behavior ORPHA:53372
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Abnormal social behavior ORPHA:436151
Narcolepsy Type 1
Transient global amnesia, Obesity ORPHA:2073
Obesity
Increased waist to hip ratio, Obesity OMIM:601665
Triglyceride Storage Disease, Type Ii
Obesity OMIM:190430
Mitochondrial Complex Iv Deficiency, Nuclear Type 14
Obesity, Cognitive impairment OMIM:619058
Spermatogenic Failure, X-Linked, 1
Obesity OMIM:305700
Childhood Disintegrative Disorder
Social and occupational deterioration, Dementia, Progressive language deterioration, Impaired soc... ORPHA:168782
Bardet-Biedl Syndrome 5
Obesity, Cognitive impairment OMIM:615983
Bardet-Biedl Syndrome 11
Obesity OMIM:615988
Thumb Stiffness-Brachydactyly-Intellectual Disability Syndrome
Obesity ORPHA:1078
Severe Early-Onset Obesity-Insulin Resistance Syndrome Due To Sh2B1 Deficiency
Obesity, Impaired social interactions ORPHA:329249
Bardet-Biedl Syndrome 14
Obesity OMIM:615991
11Q22.2Q22.3 Microdeletion Syndrome
Short attention span, Abnormal social behavior, Obesity, Attention deficit hyperactivity disorder ORPHA:444002
Bardet-Biedl Syndrome 13
Obesity OMIM:615990
Developmental Delay, Behavioral Abnormalities, And Neuropsychiatric Disorders
Overweight, Attention deficit hyperactivity disorder OMIM:620065
Intellectual Developmental Disorder, X-Linked 97
Obesity OMIM:300803
Hyperinsulinemic Hypoglycemia, Familial, 1
Large for gestational age OMIM:256450
Hypoinsulinemic Hypoglycemia With Hemihypertrophy
Truncal obesity, Obesity, Large for gestational age OMIM:240900
Hyperinsulinemic Hypoglycemia, Familial, 2
Large for gestational age OMIM:601820
Summitt Syndrome
Obesity OMIM:272350
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13
Short attention span, Inappropriate laughter, Obesity ORPHA:411515
Intellectual Developmental Disorder With Behavioral Abnormalities And Craniofacial Dysmorphism With Or Without Seizures
Obesity, Attention deficit hyperactivity disorder OMIM:618725
Obesity Due To Sim1 Deficiency
Cognitive impairment, Memory impairment, Obesity, Attention deficit hyperactivity disorder ORPHA:369873
Hsd10 Disease
Short attention span, Abnormal social behavior ORPHA:391417
Early-Onset Autosomal Dominant Alzheimer Disease
Confusion, Dementia, Semantic dementia, Memory impairment, Abnormal social behavior ORPHA:1020
Body Mass Index Quantitative Trait Locus 20
Obesity, Tall stature OMIM:618406
Cortisone Reductase Deficiency 2
Obesity OMIM:614662
Obesity And Hypopigmentation
Overgrowth, Obesity OMIM:620195
Ataxia-Oculomotor Apraxia Type 4
Short attention span, Obesity, Cognitive impairment ORPHA:459033
Ankylosing Vertebral Hyperostosis With Tylosis
Obesity ORPHA:2206
Obesity Due To Melanocortin 4 Receptor Deficiency
Childhood-onset truncal obesity, Obesity ORPHA:71529
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Increased body weight, Progressive neurologic deterioration ORPHA:276608
Phip-Related Behavioral Problems-Intellectual Disability-Obesity-Dysmorphic Features Syndrome
Increased body weight, Attention deficit hyperactivity disorder ORPHA:589905
Hepatic Veno-Occlusive Disease
Increased body weight ORPHA:890
Female Restricted Epilepsy With Intellectual Disability
Abnormal social behavior ORPHA:101039
Thyroid Hormone Resistance, Generalized, Autosomal Recessive
Small for gestational age, Increased body weight, Attention deficit hyperactivity disorder OMIM:274300
Prolactin Deficiency With Obesity And Enlarged Testes
Obesity OMIM:264120
Hypothyroidism, Congenital, Nongoitrous, 6
Increased body mass index, Increased body weight OMIM:614450
Polycystic Ovary Syndrome 1
Obesity OMIM:184700
Hypothyroidism, Central, With Testicular Enlargement
Overweight OMIM:300888
Childhood Absence Epilepsy
Abnormal social behavior, Attention deficit hyperactivity disorder ORPHA:64280
Obesity-Hypoventilation Syndrome
Obesity OMIM:257500
Hypogonadotropic Hypogonadism 27 Without Anosmia
Obesity OMIM:619755
48,Xxxy Syndrome
Attention deficit hyperactivity disorder, Abnormal social behavior, Obesity, Tall stature ORPHA:96263
Ataxia-Oculomotor Apraxia 4
Obesity, Cognitive impairment OMIM:616267
Lamb-Shaffer Syndrome
Abnormal social behavior ORPHA:530983
Congenital Hyperinsulinism Due To Hnf4A Deficiency
Increased body weight, Progressive neurologic deterioration, Large for gestational age ORPHA:263455
Metachromatic Leukodystrophy, Adult Form
Short attention span, Progressive psychomotor deterioration, Dementia, Memory impairment, Abnorma... ORPHA:309271
Metachromatic Leukodystrophy, Juvenile Form
Short attention span, Abnormal social behavior, Progressive psychomotor deterioration ORPHA:309263
Acth-Independent Macronodular Adrenal Hyperplasia 2
Abdominal obesity, Increased body weight OMIM:615954
Insulinoma
Transient global amnesia, Increased body weight ORPHA:97279
Smith-Magenis Syndrome
Increased body weight OMIM:182290
Blue Diaper Syndrome
Increased body weight ORPHA:94086
Intellectual Developmental Disorder, X-Linked, Syndromic, Nascimento Type
Increased body weight OMIM:300860
Fg Syndrome Type 1
Abnormal social behavior, Slender build, Attention deficit hyperactivity disorder ORPHA:93932
Wilson Disease
Failure to thrive, Increased body weight, Weight loss ORPHA:905
Sotos Syndrome
Attention deficit hyperactivity disorder, Overgrowth, Increased body weight, Tall stature OMIM:117550
Cushing Syndrome Due To Bilateral Macronodular Adrenocortical Disease
Memory impairment, Abdominal obesity, Increased body weight, Cognitive impairment ORPHA:189427
Pruritic Urticarial Papules And Plaques Of Pregnancy
Increased body weight ORPHA:64745
Bardet-Biedl Syndrome 12
Obesity, Cognitive impairment OMIM:615989
1P21.3 Microdeletion Syndrome
Obesity, Shyness ORPHA:293948
Prader-Willi Syndrome Due To Translocation
Attention deficit hyperactivity disorder, Abnormal social behavior, Obesity, Impaired social inte... ORPHA:177907
Pigmented Nodular Adrenocortical Disease, Primary, 4
Increased body weight OMIM:615830
Magel2-Related Prader-Willi-Like Syndrome
Abdominal obesity, Failure to thrive, Increased body weight, Cognitive impairment ORPHA:398069
Metachromatic Leukodystrophy, Late Infantile Form
Abnormal social behavior ORPHA:309256
Adrenocortical Carcinoma
Increased body weight, Weight loss ORPHA:1501
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency
Failure to thrive, Increased body weight ORPHA:264580
Koolen-De Vries Syndrome Due To A Point Mutation
Small for gestational age, Inappropriate laughter, Attention deficit hyperactivity disorder, Abno... ORPHA:363965
17Q21.31 Microdeletion Syndrome
Small for gestational age, Inappropriate laughter, Attention deficit hyperactivity disorder, Abno... ORPHA:363958
Glycogen Storage Disease Due To Liver And Muscle Phosphorylase Kinase Deficiency
Increased body weight ORPHA:79240
Non-Progressive Cerebellar Ataxia With Intellectual Disability
Memory impairment, Abnormal social behavior ORPHA:314647
Mend Syndrome
Failure to thrive, Abnormal social behavior ORPHA:401973
Niemann-Pick Disease Type C
Progressive neurologic deterioration, Dementia, Cognitive impairment, Mental deterioration, Abnor... ORPHA:646
Cushing Disease
Increased body weight, Truncal obesity, Abdominal obesity, Dementia, Memory impairment ORPHA:96253
Insulin-Resistance Syndrome Type B
Abnormality of body weight, Decreased body weight, Increased body weight, Weight loss ORPHA:2298
Dihydropyrimidine Dehydrogenase Deficiency
Abnormal social behavior ORPHA:1675
Hellp Syndrome
Increased body weight ORPHA:244242
Tuberous Sclerosis Complex
Abnormal social behavior, Attention deficit hyperactivity disorder ORPHA:805
Williams Syndrome
Failure to thrive in infancy, Obesity, Attention deficit hyperactivity disorder, Abnormal social ... ORPHA:904
Cushing Syndrome Due To Ectopic Acth Secretion
Increased body weight, Weight loss, Truncal obesity, Abdominal obesity, Dementia, Memory impairment ORPHA:99889
Carney Complex
Abdominal obesity, Increased body weight, Tall stature ORPHA:1359

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Tmprss9

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tmprss9.

No publications found that use IMPC mice or data for Tmprss9.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter