Gene Summary

Name:
transmembrane protein 132B
Synonyms:
N/A

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased lung compliance Tmem132bem1(IMPC)Ccpcz HOM   Early adult 3.69×10-05
hyperactivity Tmem132bem1(IMPC)Ccpcz HOM Early adult 2.19×10-05
abnormal liver morphology Tmem132bem1(IMPC)Ccpcz HOM Early adult 0.00
abnormal cholesterol homeostasis Tmem132bem1(IMPC)Ccpcz HOM Early adult 1.52×10-09
increased body weight Tmem132bem1(IMPC)Ccpcz HOM   Early adult 3.45×10-06

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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

X-ray

XRay Images Skull Lateral Orientation

15 Images

X-ray

XRay Images Forepaw

15 Images

X-ray

XRay Images Hind Leg and Hip

30 Images

X-ray

XRay Images Whole Body Lateral Orientation

15 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

15 Images

Human diseases caused by Tmem132b mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Tmem132b by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Attention Deficit-Hyperactivity Disorder
Attention deficit hyperactivity disorder, Hyperactivity OMIM:143465
Mental Retardation, Autosomal Dominant 45
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617600
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type
Attention deficit hyperactivity disorder, Hyperactivity OMIM:301008
Mental Retardation, Autosomal Recessive 54
Hyperactivity OMIM:617028
Schizophrenia 15
Hyperactivity OMIM:613950
Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome
Large for gestational age, Hyperactivity ORPHA:356996
22q13 deletion syndrome (Phelan-Mcdermid syndrome)
Hyperactivity DECIPHER:20
Potocki-Lupski syndrome (17p11.2 duplication syndrome)
Hyperactivity DECIPHER:19
Mental Retardation, Autosomal Recessive 3
Hyperactivity OMIM:608443
Mental Retardation, Autosomal Dominant 33
Decreased body weight, Hyperactivity OMIM:616311
Immunodeficiency 8
Hyperactivity OMIM:615401
Maturity-Onset Diabetes Of The Young, Type 11
Overweight, Obesity OMIM:613375
Hypoinsulinemic Hypoglycemia With Hemihypertrophy
Truncal obesity, Large for gestational age OMIM:240900
Obesity
Increased waist to hip ratio, Obesity OMIM:601665
Bardet-Biedl Syndrome 14
Obesity OMIM:615991
Hypoinsulinemic Hypoglycemia And Body Hemihypertrophy
Truncal obesity, Large for gestational age, Increased hepatic glycogen content ORPHA:293964
Triglyceride Storage Disease, Type Ii
Obesity OMIM:190430
Spermatogenic Failure, X-Linked, 1
Obesity OMIM:305700
Developmental And Epileptic Encephalopathy 43
Ataxia, Hyperactivity OMIM:617113
Intellectual Developmental Disorder, X-Linked 109
Hyperactivity OMIM:309548
Mental Retardation, Autosomal Dominant 52
Hyperactivity OMIM:617796
Macrosomia-Microphthalmia-Cleft Palate Syndrome
Hepatomegaly, Large for gestational age, Respiratory insufficiency ORPHA:2432
Mental Retardation, Autosomal Dominant 39
Obesity OMIM:616521
Spastic Tetraplegia, Thin Corpus Callosum, And Progressive Microcephaly
Inability to walk, Hyperactivity OMIM:616657
Insulin-Like Growth Factor I Deficiency
Decreased body weight, Hyperactivity OMIM:608747
Macrosomia With Microphthalmia, Lethal
Large for gestational age OMIM:248110
Hyperinsulinemic Hypoglycemia, Familial, 1
Large for gestational age, Pancreatic islet-cell hyperplasia OMIM:256450
Hyperinsulinemic Hypoglycemia, Familial, 2
Large for gestational age, Pancreatic islet-cell hyperplasia OMIM:601820
Mental Retardation, Autosomal Recessive 37
Hyperactivity OMIM:615493
Encephalopathy, Progressive, With Or Without Lipodystrophy
Dystonia, Ataxia, Hepatomegaly, Hypertriglyceridemia, Hyperactivity OMIM:615924
Immunodeficiency 61
Recurrent sinusitis, Attention deficit hyperactivity disorder, Obesity OMIM:300310
Severe Intellectual Disability-Hypotonia-Strabismus-Coarse Face-Planovalgus Syndrome
Gait disturbance, Obesity ORPHA:436141
Hepatic Veno-Occlusive Disease
Elevated hepatic transaminase, Hepatomegaly, Jaundice, Respiratory failure, Increased body weight ORPHA:890
Bardet-Biedl Syndrome 7
Obesity OMIM:615984
Intellectual Developmental Disorder, X-Linked 72
Hyperactivity OMIM:300271
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Hyperactivity ORPHA:436151
Bardet-Biedl Syndrome 11
Obesity OMIM:615988
Thumb Stiffness-Brachydactyly-Intellectual Disability Syndrome
Obesity ORPHA:1078
Halothane Hepatitis
Viral hepatitis, Jaundice, Hepatitis, Obesity OMIM:234350
Bardet-Biedl Syndrome 22
Obesity OMIM:617119
Carcinoma Of Esophagus
Cough, Weight loss, Obesity ORPHA:70482
Bardet-Biedl Syndrome 12
Obesity OMIM:615989
Bardet-Biedl Syndrome 13
Obesity OMIM:615990
Adenocarcinoma Of The Esophagus
Cough, Obesity ORPHA:99976
Microcephaly, Seizures, And Developmental Delay
Ataxia, Hyperactivity OMIM:613402
X-Linked Intellectual Disability, Stocco Dos Santos Type
Small for gestational age, Hyperactivity ORPHA:85288
Morbid Obesity And Spermatogenic Failure
Hepatic steatosis, Hypercholesterolemia, Hypertriglyceridemia, Obesity OMIM:615703
Sotos Syndrome 3
Hyperactivity OMIM:617169
Intellectual Developmental Disorder, X-Linked 101
Hyperactivity OMIM:300928
Spastic Paraplegia And Psychomotor Retardation With Or Without Seizures
Inability to walk, Dystonia, Ataxia, Waddling gait, Broad-based gait, Obesity OMIM:616756
Juvenile Huntington Disease
Dystonia, Gait ataxia, Ataxia, Weight loss, Bradykinesia, Progressive cerebellar ataxia, Hyperact... ORPHA:248111
Neurodevelopmental Disorder With Epilepsy And Hypoplasia Of The Corpus Callosum
Inability to walk, Gait disturbance, Dysmetria, Hyperactivity OMIM:618090
Intellectual Developmental Disorder, X-Linked 97
Obesity OMIM:300803
Smith-Magenis syndrome
Hyperactivity DECIPHER:8
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617182
Obesity Due To Melanocortin 4 Receptor Deficiency
Hypertriglyceridemia, Childhood-onset truncal obesity, Obesity ORPHA:71529
Macrosomia Adiposa Congenita
Large for gestational age, Obesity OMIM:248100
Summitt Syndrome
Obesity OMIM:272350
Obesity-Hypoventilation Syndrome
Hypoventilation, Obesity OMIM:257500
Dihydropyrimidine Dehydrogenase Deficiency
Lethargy, Failure to thrive, Hyperactivity OMIM:274270
Wilson Disease
Acute hepatitis, Cirrhosis, Elevated hepatic transaminase, Difficulty walking, Hepatic steatosis,... ORPHA:905
Retinitis Pigmentosa 71
Elevated hepatic transaminase, Pancreatitis, Obesity OMIM:616394
Mitochondrial Complex Iv Deficiency, Nuclear Type 14
Obesity OMIM:619058
Aminoacylase 1 Deficiency
Hyperactivity OMIM:609924
Chromosome 3Q29 Deletion Syndrome
Gait ataxia, Small for gestational age, Failure to thrive, Hyperactivity OMIM:609425
Hypercholesterolemia Due To Cholesterol 7Alpha-Hydroxylase Deficiency
Hypercholesterolemia, Hepatic steatosis, Cholesterol gallstones, Macrovesicular hepatic steatosis... ORPHA:209902
Intellectual Developmental Disorder With Behavioral Abnormalities And Craniofacial Dysmorphism With Or Without Seizures
Attention deficit hyperactivity disorder, Obesity OMIM:618725
Intellectual Developmental Disorder, X-Linked 107
Hyperactivity OMIM:301013
Severe Neurodegenerative Syndrome With Lipodystrophy
Cirrhosis, Gait ataxia, Hepatic steatosis, Ataxia, Hepatomegaly, Hypertriglyceridemia, Respirator... ORPHA:363400
Mental Retardation, X-Linked 77
Hyperactivity OMIM:300454
Coffin-Siris Syndrome 8
Failure to thrive, Hyperactivity OMIM:618362
Body Mass Index Quantitative Trait Locus 19
Hyperlipidemia, Obesity OMIM:617885
Hyperprolinemia, Type I
Ataxia, Hyperactivity OMIM:239500
Body Mass Index Quantitative Trait Locus 20
Tall stature, Obesity OMIM:618406
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Lethargy, Increased body weight, Pancreatic islet-cell hyperplasia ORPHA:276608
Myopathy, Congenital, With Respiratory Insufficiency And Bone Fractures
Obstructive sleep apnea, Akinesia, Obesity OMIM:618822
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13
Hyperactivity, Broad-based gait, Ataxia, Obesity ORPHA:411515
Glycine Encephalopathy
Lethargy, Hyperactivity OMIM:605899
Obesity Due To Prohormone Convertase I Deficiency
Obesity, Childhood-onset truncal obesity, Failure to thrive, Cholestasis ORPHA:71528
Obesity Due To Pro-Opiomelanocortin Deficiency
Obesity, Childhood-onset truncal obesity, Failure to thrive, Cholestasis ORPHA:71526
Obesity Due To Sim1 Deficiency
Attention deficit hyperactivity disorder, Obesity ORPHA:369873
Central Precocious Puberty
Overgrowth, Increased body weight, Obesity ORPHA:759
Clark-Baraitser Syndrome
Hyperactivity, Obesity OMIM:617752
Mental Retardation, Autosomal Recessive 13
Truncal obesity, Hyperactivity OMIM:613192
Peripheral Neuropathy, Autosomal Recessive, With Or Without Impaired Intellectual Development
Unsteady gait, Obesity OMIM:618124
Cortisone Reductase Deficiency 2
Obesity OMIM:614662
Nephronophthisis 15
Hepatic failure, Obesity OMIM:614845
Intellectual Developmental Disorder, X-Linked 104
Ataxia, Hyperactivity OMIM:300983
Joubert Syndrome 8
Ataxia, Hyperventilation, Hepatomegaly, Prolonged neonatal jaundice, Obesity OMIM:612291
Ataxia-Oculomotor Apraxia Type 4
Dystonia, Ataxia, Obesity ORPHA:459033
Ankylosing Vertebral Hyperostosis With Tylosis
Obesity ORPHA:2206
Mannosidosis, Beta A, Lysosomal
Hyperactivity OMIM:248510
Hypothyroidism, Congenital, Nongoitrous, 6
Increased body mass index, Increased body weight, Broad-based gait OMIM:614450
Intellectual Developmental Disorder With Abnormal Behavior, Microcephaly, And Short Stature
Decreased body weight, Hyperactivity OMIM:618342
8p23.1 deletion syndrome
Hyperactivity DECIPHER:39
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome
Hyperactivity, Broad-based gait, Shuffling gait, Obesity ORPHA:3077
Obesity, Early-Onset, With Adrenal Insufficiency And Red Hair
Obesity, Cholestasis OMIM:609734
Fraxe Intellectual Disability
Hyperactivity ORPHA:100973
Laurence-Moon Syndrome
Congenital hepatic fibrosis, Ataxia, Obesity ORPHA:2377
Mental Retardation, Autosomal Dominant 43
Hyperactivity OMIM:616977
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Focal pancreatic islet hyperplasia, Lethargy, Diffuse pancreatic islet hyperplasia, Hepatomegaly,... ORPHA:276575
Intellectual Disability-Obesity-Prognathism-Eye And Skin Anomalies Syndrome
Hyperactivity, Obesity ORPHA:397973
Hyperinsulinism Due To Ucp2 Deficiency
Hepatomegaly, Large for gestational age, Lethargy, Diffuse pancreatic islet hyperplasia ORPHA:276556
Mental Retardation, Autosomal Recessive 39
Hyperactivity OMIM:615541
Citrullinemia Type Ii
Hypercholesterolemia, Decreased body mass index, Lethargy, Elevated hepatic transaminase, Hepatic... ORPHA:247585
Xq25 Microduplication Syndrome
Hyperactivity ORPHA:521258
Xq25 Duplication Syndrome
Hyperactivity OMIM:300979
Hyperinsulinism Due To Hnf4A Deficiency
Lethargy, Elevated hepatic transaminase, Hepatomegaly, Increased body weight, Large for gestation... ORPHA:263455
Ck Syndrome
Slender build, Hyperactivity ORPHA:251383
Neurodevelopmental Disorder With Movement Abnormalities, Abnormal Gait, And Autistic Features
Broad-based gait, Unsteady gait, Failure to thrive, Hyperactivity OMIM:617865
Joubert Syndrome 32
Large for gestational age, Ataxia, Tall stature OMIM:617757
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency
Hypercholesterolemia, Cirrhosis, Elevated hepatic transaminase, Hepatocellular adenoma, Hepatic s... ORPHA:264580
Bardet-Biedl Syndrome 21
Overweight, Elevated hepatic transaminase, Obesity OMIM:617406
Lennox-Gastaut Syndrome
Falls, Hyperactivity ORPHA:2382
Ck Syndrome
Slender build, Hyperactivity OMIM:300831
Smith-Magenis Syndrome
Hypercholesterolemia, Hypertriglyceridemia, Increased body weight, Hyperactivity OMIM:182290
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency
Dystonia, Ataxia, Hyperactivity OMIM:612716
X-Linked Intellectual Disability, Hedera Type
Inability to walk, Gait disturbance, Unsteady gait, Dysmetria, Obesity ORPHA:93952
Cortisone Reductase Deficiency 1
Obesity OMIM:604931
Optic Atrophy 11
Dysmetria, Ataxia, Hyperactivity OMIM:617302
Abcd Syndrome
Large for gestational age OMIM:600501
Coenzyme Q10 Deficiency, Primary, 2
Pulmonary arterial hypertension, Obesity OMIM:614651
Senior-Loken Syndrome 9
Hepatic fibrosis, Obesity, Cholestasis OMIM:616629
Prolactin Deficiency With Obesity And Enlarged Testes
Obesity OMIM:264120
Obesity-Colitis-Hypothyroidism-Cardiac Hypertrophy-Developmental Delay Syndrome
Obesity ORPHA:88643
Abdominal Obesity-Metabolic Syndrome 3
Hypercholesterolemia, Truncal obesity, Abdominal obesity OMIM:615812
Phenylketonuria
Attention deficit hyperactivity disorder, Hyperactivity OMIM:261600
Macrocephaly/Autism Syndrome
Hepatomegaly, Obesity, Splenomegaly OMIM:605309
Idiopathic Neonatal Atrial Flutter
Tachypnea, Large for gestational age, Respiratory distress ORPHA:45452
Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies
Failure to thrive, Hyperactivity OMIM:615286
Graves Disease, Susceptibility To, 1
Weight loss, Hyperactivity OMIM:275000
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Lethargy, Overweight, Elevated hepatic transaminase, Respiratory distress, Episodic tachypnea, Pn... ORPHA:26793
Acth-Independent Macronodular Adrenal Hyperplasia 2
Increased body weight, Increased circulating cortisol level, Abdominal obesity OMIM:615954
13Q12.3 Microdeletion Syndrome
Hyperactivity, Obstructive sleep apnea, Failure to thrive, Obesity ORPHA:412035
Intellectual Developmental Disorder, X-Linked 30
Hyperactivity OMIM:300558
Short-Rib Thoracic Dysplasia 10 With Or Without Polydactyly
Cholestasis, Hepatic fibrosis, Hepatomegaly, Hepatic failure, Splenomegaly, Obesity OMIM:615630
Potocki-Lupski Syndrome
Sleep apnea, Hypocholesterolemia, Small for gestational age, Failure to thrive, Hyperactivity OMIM:610883
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Truncal obesity, Small for gestational age, Failure to thrive, Hyperactivity, Attention deficit h... ORPHA:73272
Hyperlysinemia, Type I
Hyperactivity OMIM:238700
Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type
Broad-based gait, Decreased body weight, Hyperactivity OMIM:300958
Polycystic Ovary Syndrome 1
Obesity OMIM:184700
Landau-Kleffner Syndrome
Steppage gait, Gait ataxia, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:98818
Hypothyroidism, Central, With Testicular Enlargement
Overweight OMIM:300888
Intellectual Developmental Disorder, X-Linked 98
Ataxia, Failure to thrive, Hyperactivity OMIM:300912
Guanidinoacetate Methyltransferase Deficiency
Dystonia, Athetosis, Ataxia, Hyperactivity ORPHA:382
Cln5 Disease
Dysdiadochokinesis, Inability to walk, Truncal ataxia, Ataxia, Unsteady gait, Dysmetria, Hyperact... ORPHA:228360
Mental Retardation, Autosomal Dominant 7
Gait disturbance, Ataxia, Failure to thrive in infancy, Small for gestational age, Hyperactivity OMIM:614104
Acrodysostosis 2 With Or Without Hormone Resistance
Hyperactivity, Obesity OMIM:614613
Neurodevelopmental Disorder With Behavioral Abnormalities, Absent Speech, And Hypotonia
Inability to walk, Hyperactivity OMIM:618718
Severe Motor And Intellectual Disabilities-Sensorineural Deafness-Dystonia Syndrome
Failure to thrive, Hyperactivity ORPHA:369939
X-Linked Intellectual Disability-Hypotonia-Movement Disorder Syndrome
Broad-based gait, Hyperactivity ORPHA:457260
X-Linked Creatine Transporter Deficiency
Dystonia, Ataxia, Cachexia, Hyperactivity, Athetosis ORPHA:52503
Succinic Semialdehyde Dehydrogenase Deficiency
Ataxia, Hyperactivity OMIM:271980
Childhood-Onset Motor And Cognitive Regression Syndrome With Extrapyramidal Movement Disorder
Inability to walk, Dystonia, Gait ataxia, Hyperactivity ORPHA:500180
Neurodevelopmental Disorder With Or Without Autism Or Seizures
Failure to thrive, Hyperactivity OMIM:619239
Intellectual Developmental Disorder, X-Linked, Syndromic, Nascimento Type
Increased body weight OMIM:300860
Intellectual Developmental Disorder, Autosomal Recessive 71
Attention deficit hyperactivity disorder, Hyperactivity OMIM:618504
Proprotein Convertase 1/3 Deficiency
Decreased circulating cortisol level, Obesity OMIM:600955
Chromosome 2Q37 Deletion Syndrome
Hyperactivity, Obesity OMIM:600430
Insulinoma
Lethargy, Increased body weight, Abnormality of the pancreatic islet cells ORPHA:97279
Mental Retardation, Autosomal Recessive 38
Unsteady gait, Hyperactivity OMIM:615516
Argininemia
Micronodular cirrhosis, Cholestasis, Hepatomegaly, Spastic gait, Hyperactivity, Portal fibrosis OMIM:207800
Dysbetalipoproteinemia
Hypercholesterolemia, Xanthelasma, Hepatic steatosis, Acute pancreatitis, Hepatomegaly, Hypertrig... ORPHA:412
Developmental Delay With Variable Intellectual Impairment And Behavioral Abnormalities
Hyperactivity, Ataxia, Tall stature, Obesity OMIM:618430
Mucopolysaccharidosis, Type Iiia
Hepatomegaly, Hyperactivity, Splenomegaly OMIM:252900
Hyperthyroidism, Nonautoimmune
Small for gestational age, Hyperactivity OMIM:609152
Infantile Neuroaxonal Dystrophy
Dystonia, Gait disturbance, Ataxia, Apneic episodes in infancy, Unsteady gait, Aspiration pneumon... ORPHA:35069
Pitt-Hopkins-Like Syndrome 1
Hyperactivity, Ataxia, Hyperventilation OMIM:610042
Macrocephaly-Intellectual Disability-Neurodevelopmental Disorder-Small Thorax Syndrome
Gait disturbance, Large for gestational age, Asthma, Hyperactivity ORPHA:457485
Pigmented Nodular Adrenocortical Disease, Primary, 4
Increased body weight, Increased circulating cortisol level, Primary hypercortisolism OMIM:615830
Resistance To Thyrotropin-Releasing Hormone Syndrome
Prolonged neonatal jaundice, Lethargy, Overweight ORPHA:99832
Chromosome 15Q25 Deletion Syndrome
Attention deficit hyperactivity disorder, Hyperactivity OMIM:614294
47,Xyy Syndrome
Attention deficit hyperactivity disorder, Asthma, Tall stature, Hyperactivity ORPHA:8
Pediatric-Onset Graves Disease
Elevated hepatic transaminase, Hepatomegaly, Jaundice, Neonatal asphyxia, Failure to thrive, Sple... ORPHA:525731
19P13.12 Microdeletion Syndrome
Hyperactivity, Hepatic steatosis, Hyperlipidemia, Obesity ORPHA:254346
Myoclonic-Astatic Epilepsy
Unsteady gait, Attention deficit hyperactivity disorder, Ataxia, Hyperactivity ORPHA:1942
Mucopolysaccharidosis, Type Iiib
Hepatomegaly, Hyperactivity, Splenomegaly OMIM:252920
Mitochondrial Complex Iii Deficiency, Nuclear Type 7
Hyperactivity OMIM:615824
Angelman Syndrome Due To Maternal 15Q11Q13 Deletion
Ataxia, Obesity, Hyperactivity, Gait imbalance, Broad-based gait ORPHA:98794
Intellectual Developmental Disorder, X-Linked 21
Hyperactivity OMIM:300143
16P12.1P12.3 Triplication Syndrome
Abnormality of the intrahepatic bile duct, Attention deficit hyperactivity disorder, Failure to t... ORPHA:485405
Angelman Syndrome
Hyperactivity, Progressive gait ataxia, Broad-based gait, Obesity OMIM:105830
Adrenocortical Carcinoma
Paradoxical increased cortisol secretion on dexamethasone suppression test, Increased circulating... ORPHA:1501
Brain-Lung-Thyroid Syndrome
Dystonia, Respiratory distress, Hyperactivity, Ataxia, Neonatal respiratory distress, Respiratory... ORPHA:209905
Mody
Overweight, Exocrine pancreatic insufficiency, Hepatocellular adenoma, Pancreatic hypoplasia, Lar... ORPHA:552
Mucopolysaccharidosis, Type Iiic
Hepatomegaly, Hyperactivity, Splenomegaly OMIM:252930
Helsmoortel-Van Der Aa Syndrome
Hyperactivity, Obesity OMIM:615873
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young
Hepatomegaly, Large for gestational age OMIM:616026
Familial Hyperthyroidism Due To Mutations In Tsh Receptor
Small for gestational age, Weight loss, Hyperactivity ORPHA:424
Abdominal Obesity-Metabolic Syndrome 4
Hypertriglyceridemia, Obesity OMIM:618620
Congenital Analbuminemia
Hypercholesterolemia, Small for gestational age, Hyperlipidemia, Obesity ORPHA:86816
Joubert Syndrome 1
Episodic tachypnea, Central apnea, Ataxia, Hepatic fibrosis, Hyperactivity, Neonatal breathing dy... OMIM:213300
X-Linked Cerebral Adrenoleukodystrophy
Inability to walk, Difficulty walking, Decreased circulating cortisol level, Gait disturbance, At... ORPHA:139396
Narcolepsy 7
Obesity OMIM:614250
Mucopolysaccharidosis, Type Iiid
Hepatomegaly, Hyperactivity, Splenomegaly OMIM:252940
X-Linked Intellectual Disability, Cabezas Type
Hyperactivity, Cachexia, Broad-based gait, Obesity ORPHA:85293
Magel2-Related Prader-Willi-Like Syndrome
Sleep apnea, Central sleep apnea, Lethargy, Increased body weight, Failure to thrive, Abdominal o... ORPHA:398069
Hypomagnesemia, Seizures, And Mental Retardation 2
Hyperactivity OMIM:618314
Pruritic Urticarial Papules And Plaques Of Pregnancy
Increased body weight ORPHA:64745
X-Linked Intellectual Disability-Acromegaly-Hyperactivity Syndrome
Hyperactivity ORPHA:85327
X-Linked Adrenoleukodystrophy
Gait disturbance, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:43
Neurodegeneration With Brain Iron Accumulation 2B
Dysdiadochokinesis, Dystonia, Gait ataxia, Bradykinesia, Dysmetria, Hyperactivity OMIM:610217
Aromatase Deficiency
Hepatic steatosis, Tall stature, Eunuchoid habitus, Hyperlipidemia, Obesity ORPHA:91
Familial Gestational Hyperthyroidism
Weight loss, Hyperactivity ORPHA:99819
Dyggve-Melchior-Clausen Disease
Inability to walk, Difficulty walking, Respiratory insufficiency due to muscle weakness, Failure ... ORPHA:239
Histidinemia
Hyperactivity ORPHA:2157
Hyperlysinemia
Recurrent pneumonia, Dysmetria, Hyperactivity, Failure to thrive, Tip-toe gait ORPHA:2203
Insulin-Resistance Syndrome Type B
Abnormality of body weight, Biliary cirrhosis, Pneumonia, Decreased body weight, Weight loss, Inc... ORPHA:2298
Spastic Paraplegia 29, Autosomal Dominant
Hyperactivity OMIM:609727
Hellp Syndrome
Pleural effusion, Increased body weight, Elevated hepatic transaminase ORPHA:244242
Distal Monosomy 12Q
Proportionate tall stature, Biliary atresia, Failure to thrive in infancy, Hyperactivity, Annular... ORPHA:96149
Monosomy 9Q22.3
Large for gestational age, Tall stature, Hyperactivity ORPHA:77301
Noonan Syndrome-Like Disorder With Loose Anagen Hair 1
Attention deficit hyperactivity disorder, Large for gestational age, Failure to thrive, Hyperacti... OMIM:607721
Neurodegeneration With Brain Iron Accumulation 1
Dystonia, Akinesia, Gait disturbance, Blepharospasm, Ataxia, Bradykinesia, Hyperactivity OMIM:234200
Choreoacanthocytosis
Elevated circulating aspartate aminotransferase concentration, Elevated circulating alanine amino... ORPHA:2388
Cerebellar Ataxia, Nonprogressive, With Mental Retardation
Dysmetria, Unsteady gait, Ataxia, Hyperactivity OMIM:614756
Tuberous Sclerosis Complex
Respiratory distress, Hepatic cysts, Respiratory failure, Hyperactivity, Attention deficit hypera... ORPHA:805
Acrodysostosis With Multiple Hormone Resistance
Hyperactivity, Obesity ORPHA:280651

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Tmem132b

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tmem132b.

No publications found that use IMPC mice or data for Tmem132b.

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MGI Allele Allele Type Produced
Tmem132bem1(IMPC)Ccpcz Exdel Mice

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