Gene: Rhbdl2

Name
rhomboid like 2
MGI ID
MGI:3608413
Synonyms
N/A
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (318) Expression & images (74) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.338 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.630 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Iris/Pupil HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.274 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.444 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Body length HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.423 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.356 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.414 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep light phase percent HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0392 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.596 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 0.125 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.340 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0321 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.750 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0710 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Dilation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Potassium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00403 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Fat mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0151 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.832 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 7f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_035_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Phosphorus HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0456 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Viability Primary Screen / Outcome HOM 41f:42m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.304 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.333 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0254 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.895 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:7m Fisher Exact Test framework 0.0627 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Triglycerides HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.471 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.946 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.548 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.871 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.337 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Total protein HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.370 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Position HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0206 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.547 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep standard deviation HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.275 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Iris transilumination HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Aspartate aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.269 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.690 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.380 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.255 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Vitreous HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 0.559 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0573 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0782 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.866 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 0.0491 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Sodium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000292 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep dark phase percent HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.503 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0696 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.136 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.482 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:7m Fisher Exact Test framework 0.113 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.934 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 7f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_034_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0243 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.108 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 7f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0416 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.212 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.945 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.895 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0612 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.211 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.319 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.303 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.371 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Synechia HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0601 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.283 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.414 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.445 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.225 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.317 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.564 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.333 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Mean cell volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.487 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep daily percent HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.110 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Free fatty acids HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0512 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 0.115 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.444 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00223 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0465 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.362 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.754 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Iris Pigmentation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0454 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.408 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.140 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 7f:2m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.176 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.391 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.783 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.227 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.106 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.298 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.693 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.492 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Area HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Fusion between cornea and lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.474 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.203 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Total bilirubin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.443 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.453 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.122 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Peak wake with respect to dark onset median HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0290 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Glucose HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000117 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.470 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.121 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0956 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Clinical Chemistry / Chloride HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.567 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0724 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Lean mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0159 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 0.138 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.324 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths standard deviation HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.617 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rhbdl2tm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rhbdl2tm1b(KOMP)Wtsi JAX Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00842 Success
Rhbdl2tm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 1 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Main olfactory bulb 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Forepaw
11 Images
Sleep Wake: Wake state (bmp file)
15 Images
X-ray: XRay Images Lateral Orientation
11 Images
X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rhbdl2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rhbdl2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Rhbdl2tm36711(L1L2_st0) Targeting vectors

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