The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cntnap3 by phenotypic similarity.
|Specific Language Impairment 2||
||Deficit in phonologic short-term memory||OMIM:606712|
|Specific Language Impairment 1||
||Deficit in phonologic short-term memory||OMIM:606711|
|Presenile Dementia, Kraepelin Type||
|Monoamine Oxidase A Deficiency||
|Alzheimer Disease 10||
||Dementia, Memory impairment||OMIM:609636|
|Microangiopathy And Leukoencephalopathy, Pontine, Autosomal Dominant||
||Dementia, Cognitive impairment||OMIM:618564|
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cntnap3.
There are 1 publication which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.||Current biology : CB (June 2021)||Cntnap3em1(IMPC)J||34143959|
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|MGI Allele||Allele Type||Produced|